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8FD3
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BU of 8fd3 by Molmil
Cryo-EM structure of Cascade-PAM complex in type I-B CAST system
Descriptor: Non-target DNA strand, RNA, Target DNA strand, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FCV
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BU of 8fcv by Molmil
Cryo-EM structure of TnsC-TniQ-DNA complex in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (60-MER), MAGNESIUM ION, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FCW
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BU of 8fcw by Molmil
Cryo-EM structure of TnsC-DNA complex in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (60-MER), MAGNESIUM ION, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FF5
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BU of 8ff5 by Molmil
Cryo-EM structure of Cascade-DNA-fullRloop in type I-B CAST system
Descriptor: Non-target DNA strand, Nostoc sp. 'Peltigera membranacea cyanobiont' 210A, RNA, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-07
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FF4
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BU of 8ff4 by Molmil
Cryo-EM structure of Cascade-DNA-TniQ-TnsC complex (composite) in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-target DNA strand, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-07
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
7VEO
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BU of 7veo by Molmil
Crystal structure of juvenile hormone acid methyltransferase silkworm JHAMT isoform3 complex with S-Adenosyl-L-homocysteine
Descriptor: Methyltranfer_dom domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Guo, P.C, Zhang, Y.S, Zhang, l, Xu, H.Y.
Deposit date:2021-09-09
Release date:2022-09-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural characterization and functional analysis of juvenile hormone acid methyltransferase JHAMT3 from the silkworm, Bombyx mori.
Insect Biochem.Mol.Biol., 151, 2022
7VS3
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BU of 7vs3 by Molmil
The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH
Descriptor: Calcium-dependent secretion activator 1, SULFATE ION
Authors:Zhou, H, Wei, Z.Q, Zhang, L, Ren, Y.J, Ma, C.
Deposit date:2021-10-25
Release date:2023-02-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis.
Structure, 31, 2023
5B0J
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BU of 5b0j by Molmil
Structure of MoeN5-Sso7d fusion protein in complex with beta-undecyl maltoside
Descriptor: MoeN5,DNA-binding protein 7d, UNDECYL-MALTOSIDE
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O.
Deposit date:2015-10-30
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
5B0M
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BU of 5b0m by Molmil
Structure of MoeN5-Sso7d fusion protein in complex with beta-dodecyl maltoside
Descriptor: DODECYL-BETA-D-MALTOSIDE, MoeN5,DNA-binding protein 7d
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O.
Deposit date:2015-11-02
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
5B0I
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BU of 5b0i by Molmil
Structure of MoeN5-Sso7d fusion protein in complex with beta-octyl glucoside
Descriptor: MoeN5,DNA-binding protein 7d, octyl beta-D-glucopyranoside
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O.
Deposit date:2015-10-30
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
5B02
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BU of 5b02 by Molmil
Structure of the prenyltransferase MoeN5 with a fusion protein tag of Sso7d
Descriptor: MoeN5,DNA-binding protein 7d
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O.
Deposit date:2015-10-27
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
5B03
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BU of 5b03 by Molmil
Structure of MoeN5-Sso7d fusion protein in complex with geranyl pyrophosphate
Descriptor: GERANYL DIPHOSPHATE, MoeN5,DNA-binding protein 7d
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O.
Deposit date:2015-10-27
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
5B00
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BU of 5b00 by Molmil
Structure of the prenyltransferase MoeN5 in complex with geranyl pyrophosphate
Descriptor: GERANYL DIPHOSPHATE, MoeN5
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T.
Deposit date:2015-10-27
Release date:2016-03-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
5B0L
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BU of 5b0l by Molmil
Structure of MoeN5-Sso7d fusion protein in complex with beta-nonyl glucoside
Descriptor: MoeN5,DNA-binding protein 7d, nonyl beta-D-glucopyranoside
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O.
Deposit date:2015-11-02
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
5B01
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BU of 5b01 by Molmil
Structure of a prenyltransferase in its unbound form
Descriptor: MoeN5
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T.
Deposit date:2015-10-27
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structure and function of a prenyltransferase
To Be Published
5B0K
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BU of 5b0k by Molmil
Structure of MoeN5-Sso7d fusion protein in complex with beta-decyl maltoside
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, MoeN5,DNA-binding protein 7d
Authors:Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T.
Deposit date:2015-10-30
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
3DOY
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BU of 3doy by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3i
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ...
Authors:Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DP3
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BU of 3dp3 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3q
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-tert-butyl-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ...
Authors:Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
5YVF
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BU of 5yvf by Molmil
Crystal structure of BFA1
Descriptor: BFA1
Authors:Pu, H, Zhang, L, Duan, Z.K, Peng, L.W, Liu, L.
Deposit date:2017-11-25
Release date:2018-08-08
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Nucleus-Encoded Protein BFA1 Promotes Efficient Assembly of the Chloroplast ATP Synthase Coupling Factor 1.
Plant Cell, 30, 2018
6JV3
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BU of 6jv3 by Molmil
Crystal structure of 5-hydoxylmethylcytosine containing decamer dsDNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*(5HC)P*GP*CP*TP*GP*G)-3')
Authors:Zhang, L, Wang, Y.X.
Deposit date:2019-04-15
Release date:2019-07-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
6JV5
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BU of 6jv5 by Molmil
Crystal structure of 5-methylcytosine containing decamer dsDNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*(5CM)P*GP*CP*TP*GP*G)-3')
Authors:Zhang, L, Wang, Y.X.
Deposit date:2019-04-15
Release date:2019-07-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
6G7M
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BU of 6g7m by Molmil
Four-site variant (Y222C, C197S, C432S, C433S) of E. coli hydrogenase-2
Descriptor: CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, Hydrogenase-2 large chain, ...
Authors:Carr, S.B, Armstrong, F.A, Zhang, L, Beaton, S.E.
Deposit date:2018-04-06
Release date:2019-04-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Direct visible light activation of a surface cysteine-engineered [NiFe]-hydrogenase by silver nanoclusters
Energy Environ Sci, 2019
6FX0
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BU of 6fx0 by Molmil
Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne
Descriptor: 6-[3-(1-adamantyl)-4-oxidanyl-phenyl]naphthalene-2-carboxylic acid, Retinoic acid receptor gamma, TETRAETHYLENE GLYCOL
Authors:Chantalat, L, Thoreau, E.
Deposit date:2018-03-08
Release date:2018-05-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne.
Bioorg. Med. Chem. Lett., 28, 2018
5N19
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BU of 5n19 by Molmil
Structure of SARS coronavirus main protease in complex with the alpha-ketoamide (S)-N-benzyl-3-((S)-2-cinnamamido-3-phenylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide
Descriptor: (S)-N-benzyl-3-((S)-2-cinnamamido-3-phenylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide, DIMETHYL SULFOXIDE, SARS coronavirus main protease
Authors:Zhang, L, Ma, Q, Hilgenfeld, R.
Deposit date:2017-02-05
Release date:2018-02-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published
5N5O
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BU of 5n5o by Molmil
Structure of SARS coronavirus main protease in complex with the alpha-ketoamide (S)-N-benzyl-3-((S)-2-cinnamamido-3-cyclopropylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide (Cinnamoyl-cyclopropylalanine-GlnLactam-CO-CO-NH-benzyl)
Descriptor: (2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanoyl]amino]-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-~{N}-(phenylmethyl)butanamide, Replicase polyprotein 1ab
Authors:Zhang, L, Hilgenfeld, R.
Deposit date:2017-02-14
Release date:2018-03-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published

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数据于2024-06-19公开中

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