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4Z55
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BU of 4z55 by Molmil
Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
Descriptor: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Authors:Lee, C.C, Spraggon, G.
Deposit date:2015-04-02
Release date:2016-02-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5IMM
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BU of 5imm by Molmil
Nanobody targeting mouse Vsig4 in Spacegroup P212121
Descriptor: Nanobody, Protein Vsig4
Authors:Wen, Y, Zheng, F.
Deposit date:2016-03-06
Release date:2017-01-11
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
1QQL
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BU of 1qql by Molmil
THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Descriptor: FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Authors:Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1QQK
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BU of 1qqk by Molmil
THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR)
Descriptor: FIBROBLAST GROWTH FACTOR 7
Authors:Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
5VK0
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BU of 5vk0 by Molmil
Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
Authors:Tolbert, W.D, Gohain, N, Pazgier, M.
Deposit date:2017-04-20
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
5VK1
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BU of 5vk1 by Molmil
Crystal structure of human MDM4 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
Descriptor: Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI, Protein Mdm4
Authors:Tolbert, W.D, Gohain, N, Pazgier, M.
Deposit date:2017-04-20
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
6PLX
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BU of 6plx by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, desensitized state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLZ
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BU of 6plz by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, closed state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLY
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BU of 6ply by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, open state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLR
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BU of 6plr by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with glycine in nanodisc, desensitized state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, Glycine receptor subunit alphaZ1, ...
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLO
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BU of 6plo by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA,open state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLT
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BU of 6plt by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, closed state
Descriptor: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, ...
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLU
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BU of 6plu by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, desensitized state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, ...
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLS
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BU of 6pls by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, desensitized state
Descriptor: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, ...
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLV
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BU of 6plv by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, ...
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLQ
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BU of 6plq by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, super-open state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM1
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BU of 6pm1 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, desensitized state
Descriptor: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM0
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BU of 6pm0 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, super-open state
Descriptor: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM4
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BU of 6pm4 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, super-open state
Descriptor: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM3
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BU of 6pm3 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, closed state
Descriptor: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM5
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BU of 6pm5 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, desensitized state
Descriptor: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM2
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BU of 6pm2 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, open state
Descriptor: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLP
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BU of 6plp by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, desensitized state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM6
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BU of 6pm6 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, open state
Descriptor: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLW
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BU of 6plw by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, super-open state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021

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数据于2024-05-29公开中

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