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7MZB
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BU of 7mzb by Molmil
Cryo-EM structure of minimal TRPV1 with 3 bound RTX and 1 perturbed PI
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZC
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BU of 7mzc by Molmil
Cryo-EM structure of minimal TRPV1 with RTX bound in C1 state
Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZA
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BU of 7mza by Molmil
Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZ9
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BU of 7mz9 by Molmil
Cryo-EM structure of minimal TRPV1 with 1 partially bound RTX
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZ7
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BU of 7mz7 by Molmil
Cryo-EM structure of minimal TRPV1 with 4 partially bound RTX
Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZD
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BU of 7mzd by Molmil
Cryo-EM structure of minimal TRPV1 with RTX bound in C2 state
Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
1BNP
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BU of 1bnp by Molmil
NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, 55 STRUCTURES
Descriptor: DNA POLYMERASE BETA
Authors:Liu, D.-J, Prasad, R, Wilson, S.H, Derose, E.F, Mullen, G.P.
Deposit date:1996-04-25
Release date:1996-12-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface.
Biochemistry, 35, 1996
1BNO
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BU of 1bno by Molmil
NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, MINIMIZED AVERAGE STRUCTURE
Descriptor: DNA POLYMERASE BETA
Authors:Liu, D.-J, Prasad, R, Wilson, S.H, Derose, E.F, Mullen, G.P.
Deposit date:1996-04-25
Release date:1996-12-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface.
Biochemistry, 35, 1996
7T2Z
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BU of 7t2z by Molmil
The structure of Haemophilus influenzae Rd KW20 nitroreductase complexed with 1-methyl-5-nitroimidazole
Descriptor: 1,2-ETHANEDIOL, 1-methyl-5-nitro-1H-imidazole, ACETIC ACID, ...
Authors:Wanniarachchi, T.N, Bruner, S.D.
Deposit date:2021-12-06
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2547 Å)
Cite:Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles.
Rsc Chem Biol, 3, 2022
7T33
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BU of 7t33 by Molmil
The structure of Haemophilus influenzae Rd KW20 nitroreductase complexed with nicotinic acid
Descriptor: FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, Putative NAD(P)H nitroreductase, ...
Authors:Wanniarachchi, T.N, Bruner, S.D.
Deposit date:2021-12-06
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles.
Rsc Chem Biol, 3, 2022
6JL7
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BU of 6jl7 by Molmil
crystal structure of TBC1D23 N terminal domain
Descriptor: TBC1 domain family member 23
Authors:Sun, Q, Hu, W, Jia, D.
Deposit date:2019-03-04
Release date:2020-03-04
Last modified:2021-09-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of TBC1D23 N-terminus reveals a novel role for rhodanese domain.
Plos Biol., 18, 2020
7F29
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BU of 7f29 by Molmil
Cryo-EM structure of the fibril formed by disaccharide-modified amyloid-beta(1-42)
Descriptor: ACETIC ACID, Amyloid-beta A4 protein, beta-D-galactopyranose-(1-3)-2-amino-2-deoxy-alpha-D-galactopyranose
Authors:Xia, W.C, Sun, Y.P, Liu, C.
Deposit date:2021-06-10
Release date:2022-07-13
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:O-Glycosylation Induces Amyloid-beta To Form New Fibril Polymorphs Vulnerable for Degradation
J.Am.Chem.Soc., 143, 2021
1YYB
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BU of 1yyb by Molmil
Solution structure of 1-26 fragment of human programmed cell death 5 protein
Descriptor: Programmed cell death protein 5
Authors:Liu, D.S, Feng, Y.G, Yao, H.W, Wang, J.F.
Deposit date:2005-02-24
Release date:2005-09-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The N-terminal 26-residue fragment of human programmed cell death 5 protein can form a stable alpha-helix having unique electrostatic potential character.
Biochem.J., 392, 2005
7FH1
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BU of 7fh1 by Molmil
Structure of the human Meckelin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Meckelin, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Gong, D.S.
Deposit date:2021-07-29
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structure of the human Meckel-Gruber protein Meckelin.
Sci Adv, 7, 2021
4J51
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BU of 4j51 by Molmil
Cyrstal structure of protein tyrosine phosphatase Lyp catalytic domain complex with small molecular inhibitor L75N04
Descriptor: 3-[(3-chlorophenyl)ethynyl]-2-{4-[2-(cyclopropylamino)-2-oxoethoxy]phenyl}-6-hydroxy-1-benzofuran-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 22
Authors:Liu, D, He, Y, Zhang, Z.-Y.
Deposit date:2013-02-07
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune Diseases.
J.Med.Chem., 56, 2013
7VKI
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BU of 7vki by Molmil
ESRP1 qRRM2 in complex with 12mer-RNA
Descriptor: Epithelial splicing regulatory protein 1, RNA (12-mer)
Authors:Wu, B.X, Patel, D.J.
Deposit date:2021-09-30
Release date:2022-10-05
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:ESRP1 controls biogenesis and function of a large abundant multiexon circRNA.
Nucleic Acids Res., 2023
5HEK
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BU of 5hek by Molmil
crystal structure of M1.HpyAVI
Descriptor: Adenine specific DNA methyltransferase (DpnA)
Authors:Ma, B, Zhang, H, Liu, W.
Deposit date:2016-01-06
Release date:2016-11-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori
Oncotarget, 7, 2016
1DK3
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BU of 1dk3 by Molmil
REFINED SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA
Descriptor: DNA POLYMERASE BETA
Authors:Maciejewski, M.W, Prasad, R, Liu, D.-J, Wilson, S.H, Mullen, G.P.
Deposit date:1999-12-06
Release date:2000-02-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity.
J.Mol.Biol., 296, 2000
1DK2
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BU of 1dk2 by Molmil
REFINED SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA
Descriptor: DNA POLYMERASE BETA
Authors:Maciejewski, M.W, Prasad, R, Liu, D.-J, Wilson, S.H, Mullen, G.P.
Deposit date:1999-12-06
Release date:2000-02-14
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity.
J.Mol.Biol., 296, 2000
7O3U
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BU of 7o3u by Molmil
The crystal structure of obelin from Obelia longissima bound with v-coelenterazine
Descriptor: CALCIUM ION, Obelin, v-coelenterazine
Authors:Larionova, M.D, Wu, L.J, Vysotski, E.S, Liu, Z.-J.
Deposit date:2021-04-03
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of semisynthetic obelin-v.
Protein Sci., 31, 2022
6JM5
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BU of 6jm5 by Molmil
Crystal structure of TBC1D23 C terminal domain
Descriptor: SODIUM ION, TBC1 domain family member 23
Authors:Sun, Q, Huang, W.
Deposit date:2019-03-07
Release date:2019-10-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH.
Proc.Natl.Acad.Sci.USA, 116, 2019
6ACU
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BU of 6acu by Molmil
The structure of CVA10 virus mature virion
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
Deposit date:2018-07-27
Release date:2018-11-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6ACW
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BU of 6acw by Molmil
The structure of CVA10 virus procapsid particle
Descriptor: VP0, VP1, VP3
Authors:Zhu, R, Xu, L.F, Zheng, Q.B, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
Deposit date:2018-07-27
Release date:2018-11-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6AD1
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BU of 6ad1 by Molmil
The structure of CVA10 procapsid from its complex with Fab 2G8
Descriptor: VP0, VP1, VP3
Authors:Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
Deposit date:2018-07-28
Release date:2018-11-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
8YJO
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BU of 8yjo by Molmil
Structure of E. coli glycyl radical enzyme PflD with bound malonate
Descriptor: MALONATE ION, Probable dehydratase PflD
Authors:Xue, B, Wei, Y, Robinson, R.C, Yew, W.S, Zhang, Y.
Deposit date:2024-03-02
Release date:2024-10-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Widespread Radical-Mediated Glycolysis Pathway.
J.Am.Chem.Soc., 146, 2024

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数据于2024-10-16公开中

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