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7RU6
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BU of 7ru6 by Molmil
Cryo-EM structure of the HIV-1 restriction factor human SERINC3
Descriptor: Serine incorporator 3, SiA
Authors:Purdy, M.D, Leonhardt, S.A, Yeager, M.
Deposit date:2021-08-16
Release date:2022-08-24
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.
Nat Commun, 14, 2023
7RUG
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BU of 7rug by Molmil
Human SERINC3-DeltaICL4
Descriptor: Serine incorporator 3, SiA
Authors:Purdy, M.D, Leonhardt, S.A, Yeager, M.
Deposit date:2021-08-17
Release date:2022-08-24
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.
Nat Commun, 14, 2023
9DER
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BU of 9der by Molmil
Cryo-EM Structures of Full-Length Integrin alphaIIbbeta3 in Native Lipids Complexed with Tirofiban
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-IIb, ...
Authors:Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
Deposit date:2024-08-29
Release date:2024-10-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Platelet integrin alpha IIb beta 3 plays a key role in a venous thrombogenesis mouse model.
Nat Commun, 15, 2024
9DEQ
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BU of 9deq by Molmil
Cryo-EM structures of full-length integrin alphaIIbbeta3 in native lipids complexed with modified tirofiban
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
Deposit date:2024-08-29
Release date:2024-10-16
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Platelet integrin alpha IIb beta 3 plays a key role in a venous thrombogenesis mouse model.
Nat Commun, 15, 2024
3DIK
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BU of 3dik by Molmil
Pseudo-atomic model of the HIV-1 CA hexameric lattice
Descriptor: Capsid protein p24
Authors:Ganser-Pornillos, B.K, Cheng, A, Yeager, M.
Deposit date:2008-06-20
Release date:2008-09-16
Last modified:2024-02-21
Method:ELECTRON CRYSTALLOGRAPHY (9 Å)
Cite:Structure of full-length HIV-1 CA: a model for the mature capsid lattice
Cell(Cambridge,Mass.), 131, 2007
8T2U
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BU of 8t2u by Molmil
Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids complexed with Eptifibatide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
Deposit date:2023-06-06
Release date:2023-07-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
8T2V
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BU of 8t2v by Molmil
Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
Deposit date:2023-06-06
Release date:2023-07-26
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
1F2N
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BU of 1f2n by Molmil
RICE YELLOW MOTTLE VIRUS
Descriptor: CALCIUM ION, CAPSID PROTEIN
Authors:Qu, C, Liljas, L, Opalka, N, Brugidou, C, Yeager, M, Beachy, R.N, Fauquet, C.M, Johnson, J.E, Lin, T.
Deposit date:2000-05-26
Release date:2000-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:3D domain swapping modulates the stability of members of an icosahedral virus group.
Structure Fold.Des., 8, 2000
1F8V
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BU of 1f8v by Molmil
THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA
Descriptor: CALCIUM ION, MATURE CAPSID PROTEIN BETA, MATURE CAPSID PROTEIN GAMMA, ...
Authors:Tang, L, Johnson, K.N, Ball, L.A, Lin, T, Yeager, M, Johnson, J.E.
Deposit date:2000-07-05
Release date:2000-12-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA.
Nat.Struct.Biol., 8, 2001
6UVS
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BU of 6uvs by Molmil
Human Connexin-26 (Low pH open conformation)
Descriptor: Gap junction beta-2 protein
Authors:Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M.
Deposit date:2019-11-04
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels.
Cell Rep, 31, 2020
6UVT
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BU of 6uvt by Molmil
Human Connexin-26 (Low pH closed conformation)
Descriptor: Gap junction beta-2 protein
Authors:Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M.
Deposit date:2019-11-04
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:A Steric 'Ball-and-Chain' Mechanism for pH-Mediated Regulation of Gap Junction Channels
Cell Rep, 31, 2020
6UVR
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BU of 6uvr by Molmil
Human Connexin-26 (Neutral pH open conformation)
Descriptor: Gap junction beta-2 protein
Authors:Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M.
Deposit date:2019-11-04
Release date:2020-04-29
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels.
Cell Rep, 31, 2020
5ERA
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BU of 5era by Molmil
Human Connexin-26 (Calcium-free)
Descriptor: Gap junction beta-2 protein
Authors:Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J.
Deposit date:2015-11-13
Release date:2016-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels.
Nat Commun, 7, 2016
5ER7
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BU of 5er7 by Molmil
Connexin-26 Bound to Calcium
Descriptor: CALCIUM ION, Gap junction beta-2 protein
Authors:Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J.
Deposit date:2015-11-13
Release date:2016-01-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.286 Å)
Cite:An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels.
Nat Commun, 7, 2016
7ZUD
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BU of 7zud by Molmil
Crystal structure of HIV-1 capsid IP6-CPSF6 complex
Descriptor: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE
Authors:Nicastro, G, Taylor, I.A.
Deposit date:2022-05-12
Release date:2022-07-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.
J.Mol.Biol., 434, 2022
6CBV
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BU of 6cbv by Molmil
Crystal structure of BRIL bound to an affinity matured synthetic antibody.
Descriptor: BRIL, FORMIC ACID, GLYCEROL, ...
Authors:Mukherjee, S, Skrobek, B, Kossiakoff, A.A.
Deposit date:2018-02-05
Release date:2019-02-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.872 Å)
Cite:Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
4WYM
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BU of 4wym by Molmil
Structural basis of HIV-1 capsid recognition by CPSF6
Descriptor: Capsid protein p24, ISOFORM 2 OF CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6
Authors:Battacharya, A, Taylor, A.B, Hart, P.J, Ivanov, D.N.
Deposit date:2014-11-17
Release date:2014-12-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
1OQV
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BU of 1oqv by Molmil
Structure of TcpA, the Type IV pilin subunit from the toxin co-regulated pilus of Vibrio cholerae classical biotype
Descriptor: GLYCEROL, toxin-coregulated pilus subunit
Authors:Craig, L, Tainer, J.A.
Deposit date:2003-03-11
Release date:2003-06-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Type IV Pilin Structure and Assembly: X-Ray and EM Analyses of Vibrio cholerae Toxin-Coregulated Pilus and Pseudomonas aeruginosa PAK Pilin
Mol.Cell, 11, 2003
1OQW
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BU of 1oqw by Molmil
Full-Length PAK Pilin from Pseudomonas aeruginosa
Descriptor: Fimbrial protein
Authors:Craig, L, Arvai, A.S, Forest, K.T, Tainer, J.A.
Deposit date:2003-03-11
Release date:2003-06-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Type IV Pilin Structure and Assembly: X-Ray and EM Analyses of Vibrio cholerae Toxin-Coregulated Pilus and Pseudomonas aeruginosa PAK Pilin
Mol.Cell, 11, 2003
4QNB
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BU of 4qnb by Molmil
Disulfide stabilized HIV-1 CA hexamer in complex with PHENYL-L-PHENYLALANINAMIDE inhibitor
Descriptor: CAPSID PROTEIN P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Pornillos, O.
Deposit date:2014-06-17
Release date:2014-12-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
3MGE
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BU of 3mge by Molmil
X-ray Structure of Hexameric HIV-1 CA
Descriptor: 1,2-ETHANEDIOL, Capsid protein p24
Authors:Pornillos, O.
Deposit date:2010-04-05
Release date:2010-07-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Disulfide Bond Stabilization of the Hexameric Capsomer of Human Immunodeficiency Virus.
J.Mol.Biol., 401, 2010
6PEK
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BU of 6pek by Molmil
Structure of Spastin Hexamer (Subunit A-E) in complex with substrate peptide
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P.
Deposit date:2019-06-20
Release date:2019-12-04
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.
J.Biol.Chem., 295, 2020
6PEN
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BU of 6pen by Molmil
Structure of Spastin Hexamer (whole model) in complex with substrate peptide
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, EYEYEYEYEY, ...
Authors:Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P.
Deposit date:2019-06-20
Release date:2019-12-04
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.
J.Biol.Chem., 295, 2020
6N3J
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BU of 6n3j by Molmil
MicroED Structure of the CTD-SP1 fragment of HIV-1 Gag
Descriptor: CTD-SP1 fragment of HIV-1 Gag
Authors:Purdy, M.D, Shi, D, Hattne, J, Chrustowicz, J.
Deposit date:2018-11-15
Release date:2018-12-12
Last modified:2023-10-11
Method:ELECTRON CRYSTALLOGRAPHY (3 Å)
Cite:MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N3U
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BU of 6n3u by Molmil
MicroED Structure of the CTD-SP1 fragment of HIV-1 Gag with bound maturation inhibitor Bevirimat.
Descriptor: CTD-SP1 fragment of HIV-1 Gag
Authors:Purdy, M.D, Shi, D, Hattne, J, Chrustowicz, J.
Deposit date:2018-11-16
Release date:2018-12-12
Last modified:2023-10-25
Method:ELECTRON CRYSTALLOGRAPHY (2.9 Å)
Cite:MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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