1WSP
| Crystal structure of axin dix domain | Descriptor: | Axin 1 protein, BENZOIC ACID, MERCURY (II) ION | Authors: | Shibata, N, Hanamura, T, Yamamoto, R, Ueda, Y, Yamamoto, H, Kikuchi, A, Higuchi, Y. | Deposit date: | 2004-11-08 | Release date: | 2006-02-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of axin dix domain to be published
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1NBK
| The structure of RNA aptamer for HIV Tat complexed with two argininamide molecules | Descriptor: | 2-AMINO-5-GUANIDINO-PENTANOIC ACID, RNA aptamer | Authors: | Matsugami, A, Kobayashi, S, Ouhashi, K, Uesugi, S, Yamamoto, R, Taira, K, Nishikawa, S, Kumar, P.K.R, Katahira, M. | Deposit date: | 2002-12-03 | Release date: | 2003-12-03 | Last modified: | 2024-09-18 | Method: | SOLUTION NMR | Cite: | Structural Basis of the Highly Efficient Trapping of the HIV Tat Protein by an RNA Aptamer Structure, 11, 2003
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3WBI
| Crystal structure analysis of eukaryotic translation initiation factor 5B structure I | Descriptor: | Eukaryotic translation initiation factor 5B | Authors: | Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M. | Deposit date: | 2013-05-20 | Release date: | 2014-11-19 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A Acta Crystallogr.,Sect.D, 70, 2014
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3WBJ
| Crystal structure analysis of eukaryotic translation initiation factor 5B structure II | Descriptor: | Eukaryotic translation initiation factor 5B | Authors: | Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M. | Deposit date: | 2013-05-20 | Release date: | 2014-11-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A Acta Crystallogr.,Sect.D, 70, 2014
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3WBK
| crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex | Descriptor: | Eukaryotic translation initiation factor 1A, Eukaryotic translation initiation factor 5B | Authors: | Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M. | Deposit date: | 2013-05-20 | Release date: | 2014-11-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A Acta Crystallogr.,Sect.D, 70, 2014
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8RYK
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8RYS
| Human IL-1beta, unliganded | Descriptor: | Interleukin-1 beta, SULFATE ION | Authors: | Rondeau, J.-M, Lehmann, S. | Deposit date: | 2024-02-09 | Release date: | 2024-03-06 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67, 2024
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8RZB
| IL-1beta in complex with covalent DEL hit | Descriptor: | 8-[4-methyl-3-(trifluoromethyl)phenyl]-2-[[(7S)-7-(2-morpholin-4-ylethylcarbamoyl)-4-(phenylsulfonyl)-1,4-diazepan-1-yl]carbonyl]imidazo[1,2-a]pyridine-6-carboxylic acid, Interleukin-1 beta | Authors: | Rondeau, J.-M, Lehmann, S. | Deposit date: | 2024-02-12 | Release date: | 2024-05-22 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.836 Å) | Cite: | Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67, 2024
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8C3U
| Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist | Descriptor: | (S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid, Interleukin-1 beta | Authors: | Rondeau, J.-M, Lehmann, S, Koch, E. | Deposit date: | 2022-12-28 | Release date: | 2023-09-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.945 Å) | Cite: | Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1 beta. Nat Commun, 14, 2023
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2D5G
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