6BS9
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![BU of 6bs9 by Molmil](/molmil-images/mine/6bs9) | Stage III sporulation protein AB (SpoIIIAB) | Descriptor: | SULFATE ION, Stage III sporulation protein AB | Authors: | Strynadka, N.C.J, Zeytuni, N, Camp, A.H, Flanagan, K.A. | Deposit date: | 2017-12-01 | Release date: | 2018-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural characterization of SpoIIIAB sporulation-essential protein in Bacillus subtilis. J. Struct. Biol., 202, 2018
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6DCS
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![BU of 6dcs by Molmil](/molmil-images/mine/6dcs) | Stage III sporulation protein AF (SpoIIIAF) | Descriptor: | SULFATE ION, Stage III sporulation protein AF | Authors: | Strynadka, N.C.J, Zeytuni, N, Camp, A.H, Flanagan, K.A. | Deposit date: | 2018-05-08 | Release date: | 2018-07-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and biochemical characterization of SpoIIIAF, a component of a sporulation-essential channel in Bacillus subtilis. J. Struct. Biol., 204, 2018
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6PEE
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6ZTG
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![BU of 6ztg by Molmil](/molmil-images/mine/6ztg) | Spor protein DedD | Descriptor: | Cell division protein DedD | Authors: | Pazos, M, Peters, K, Boes, A, Safaei, Y, Kenward, C, Caveney, N.A, Laguri, C, Breukink, E, Strynadka, N.C.J, Simorre, J.P, Terrak, M, Vollmer, W. | Deposit date: | 2020-07-20 | Release date: | 2020-11-11 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. Mbio, 11, 2020
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5TXI
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![BU of 5txi by Molmil](/molmil-images/mine/5txi) | Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole | Descriptor: | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... | Authors: | Alexander, J.A.N, Strynadka, N.C.J. | Deposit date: | 2016-11-16 | Release date: | 2018-05-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
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1KN9
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7UZ2
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![BU of 7uz2 by Molmil](/molmil-images/mine/7uz2) | Structure of beta-glycosidase from Sulfolobus solfataricus in complex with C5a-fluoro-valienide. | Descriptor: | (1R,2S,3R,4R)-5-fluoro-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, Beta-galactosidase | Authors: | Danby, P.M, Jeong, A, Sim, L, Sweeney, R.P, Wardman, J.F, Geissner, A, Worrall, L.J, Strynadka, N.C.J, Withers, S.G. | Deposit date: | 2022-05-08 | Release date: | 2023-04-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors. Angew.Chem.Int.Ed.Engl., 62, 2023
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7UZ1
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![BU of 7uz1 by Molmil](/molmil-images/mine/7uz1) | Structure of beta-glycosidase from Sulfolobus solfataricus in complex with C5a-bromo-valienide. | Descriptor: | (1R,2S,3R,4R)-5-bromo-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, 1,2-ETHANEDIOL, Beta-galactosidase | Authors: | Danby, P.M, Jeong, A, Sim, L, Sweeney, R.P, Wardman, J.F, Karimi, R, Geissner, A, Worrall, L.J, Strynadka, N.C.J, Withers, S.G. | Deposit date: | 2022-05-08 | Release date: | 2023-04-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors. Angew.Chem.Int.Ed.Engl., 62, 2023
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7TC5
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![BU of 7tc5 by Molmil](/molmil-images/mine/7tc5) | All Phe-Azurin variant - F15Y | Descriptor: | Azurin, COPPER (II) ION, NITRATE ION, ... | Authors: | Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J. | Deposit date: | 2021-12-22 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorg.Chem., 61, 2022
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7TC6
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![BU of 7tc6 by Molmil](/molmil-images/mine/7tc6) | All Phe-Azurin variant - F15W | Descriptor: | Azurin, COPPER (II) ION, NITRATE ION | Authors: | Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J. | Deposit date: | 2021-12-22 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorg.Chem., 61, 2022
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2DRJ
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2F2H
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![BU of 2f2h by Molmil](/molmil-images/mine/2f2h) | Structure of the YicI thiosugar Michaelis complex | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-NITROPHENYL 6-THIO-6-S-ALPHA-D-XYLOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, GLYCEROL, ... | Authors: | Kim, Y.-W, Lovering, A.L, Strynadka, N.C.J, Withers, S.G. | Deposit date: | 2005-11-16 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Expanding the Thioglycoligase Strategy to the Synthesis of alpha-linked Thioglycosides Allows Structural Investigation of the Parent Enzyme/Substrate Complex J.Am.Chem.Soc., 128, 2006
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7LBU
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![BU of 7lbu by Molmil](/molmil-images/mine/7lbu) | Crystal structure of the Propionibacterium acnes surface sialidase | Descriptor: | ACETATE ION, Exo-alpha-sialidase, PHOSPHATE ION | Authors: | Yu, A.C.Y, Volkers, G, Strynadka, N.C.J. | Deposit date: | 2021-01-08 | Release date: | 2021-12-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases. Glycobiology, 32, 2022
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7LBV
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![BU of 7lbv by Molmil](/molmil-images/mine/7lbv) | Crystal structure of the Propionibacterium acnes surface sialidase in complex with Neu5Ac2en | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Exo-alpha-sialidase, PHOSPHATE ION | Authors: | Yu, A.C.Y, Volkers, G, Strynadka, N.C.J. | Deposit date: | 2021-01-09 | Release date: | 2021-12-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases. Glycobiology, 32, 2022
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7LQ6
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![BU of 7lq6 by Molmil](/molmil-images/mine/7lq6) | CryoEM structure of Escherichia coli PBP1b | Descriptor: | Penicillin-binding protein 1B | Authors: | Caveney, N.A, Workman, S.D, Yan, R, Atkinson, C.E, Yu, Z, Strynadka, N.C.J. | Deposit date: | 2021-02-13 | Release date: | 2021-05-26 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | CryoEM structure of the antibacterial target PBP1b at 3.3 angstrom resolution. Nat Commun, 12, 2021
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6C39
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6C3K
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1Y5I
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![BU of 1y5i by Molmil](/molmil-images/mine/1y5i) | The crystal structure of the NarGHI mutant NarI-K86A | Descriptor: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, FE3-S4 CLUSTER, ... | Authors: | Bertero, M.G, Rothery, R.A, Boroumand, N, Palak, M, Blasco, F, Ginet, N, Weiner, J.H, Strynadka, N.C.J. | Deposit date: | 2004-12-02 | Release date: | 2005-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Biochemical Characterization of a Quinol Binding Site of Escherichia coli Nitrate Reductase A J.Biol.Chem., 280, 2005
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6PEM
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![BU of 6pem by Molmil](/molmil-images/mine/6pem) | Focussed refinement of InvGN0N1:SpaPQR:PrgHK from Salmonella SPI-1 injectisome NC-base | Descriptor: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | Authors: | Hu, J, Worrall, L.J, Strynadka, N.C.J. | Deposit date: | 2019-06-20 | Release date: | 2019-10-23 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. Nat Microbiol, 4, 2019
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6Q15
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![BU of 6q15 by Molmil](/molmil-images/mine/6q15) | Structure of the Salmonella SPI-1 injectisome needle complex | Descriptor: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | Authors: | Hu, J, Worrall, L.J, Strynadka, N.C.J. | Deposit date: | 2019-08-02 | Release date: | 2019-10-23 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (5.15 Å) | Cite: | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. Nat Microbiol, 4, 2019
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6Q14
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![BU of 6q14 by Molmil](/molmil-images/mine/6q14) | Structure of the Salmonella SPI-1 injectisome NC-base | Descriptor: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | Authors: | Hu, J, Worrall, L.J, Strynadka, N.C.J. | Deposit date: | 2019-08-02 | Release date: | 2019-10-23 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. Nat Microbiol, 4, 2019
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6Q16
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![BU of 6q16 by Molmil](/molmil-images/mine/6q16) | Focussed refinement of InvGN0N1:PrgHK:SpaPQR:PrgIJ from Salmonella SPI-1 injectisome NC-base | Descriptor: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | Authors: | Hu, J, Worrall, L.J, Strynadka, N.C.J. | Deposit date: | 2019-08-02 | Release date: | 2019-10-23 | Last modified: | 2020-01-15 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. Nat Microbiol, 4, 2019
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5WD7
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![BU of 5wd7 by Molmil](/molmil-images/mine/5wd7) | Structure of a bacterial polysialyltransferase in complex with fondaparinux | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, SULFATE ION, SiaD | Authors: | Worrall, L.J, Lizak, C, Strynadka, N.C.J. | Deposit date: | 2017-07-04 | Release date: | 2017-08-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid. Sci Rep, 7, 2017
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6UEX
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![BU of 6uex by Molmil](/molmil-images/mine/6uex) | Crystal structure of S. aureus LcpA in complex with octaprenyl-pyrophosphate-GlcNAc | Descriptor: | 2-(acetylamino)-2-deoxy-1-O-[(S)-hydroxy{[(S)-hydroxy{[(2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl]oxy}phosphoryl]oxy}phosphoryl]-alpha-D-glucopyranose, GLYCEROL, Regulatory protein MsrR, ... | Authors: | Li, F.K.K, Strynadka, N.C.J. | Deposit date: | 2019-09-23 | Release date: | 2020-01-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase. J.Biol.Chem., 295, 2020
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6UF6
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![BU of 6uf6 by Molmil](/molmil-images/mine/6uf6) | Crystal structure of B. subtilis TagU | Descriptor: | GLYCEROL, Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU, SULFATE ION | Authors: | Li, F.K.K, Strynadka, N.C.J. | Deposit date: | 2019-09-23 | Release date: | 2020-01-29 | Last modified: | 2020-03-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase. J.Biol.Chem., 295, 2020
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