7LBV

Crystal structure of the Propionibacterium acnes surface sialidase in complex with Neu5Ac2en

Summary for 7LBV

Entry DOI	10.2210/pdb7lbv/pdb
Related	7LBU
Descriptor	Exo-alpha-sialidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	acne, hydrolase
Biological source	Cutibacterium acnes (Propionibacterium acnes)
Total number of polymer chains	1
Total formula weight	49175.55
Authors	Yu, A.C.Y.,Volkers, G.,Strynadka, N.C.J. (deposition date: 2021-01-09, release date: 2021-12-08, Last modification date: 2023-10-18)
Primary citation	Yu, A.C.Y.,Volkers, G.,Jongkees, S.A.K.,Worrall, L.J.,Withers, S.G.,Strynadka, N.C.J. Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases. Glycobiology, 32:162-170, 2022 Cited by PubMed: 34792586 DOI: 10.1093/glycob/cwab094 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation