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3FHA
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BU of 3fha by Molmil
Structure of endo-beta-N-acetylglucosaminidase A
Descriptor: CALCIUM ION, Endo-beta-N-acetylglucosaminidase, GLYCEROL, ...
Authors:Yin, J, Li, L, Shaw, N, Li, Y, Song, J.K, Zhang, W, Xia, C, Zhang, R, Joachimiak, A, Zhang, H.C, Wang, L.X, Wang, P, Liu, Z.J.
Deposit date:2008-12-09
Release date:2009-04-28
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A.
Plos One, 4, 2009
8DS8
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BU of 8ds8 by Molmil
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
Descriptor: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
Authors:Song, J.K, Lu, J.W.
Deposit date:2022-07-21
Release date:2023-08-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
8EIH
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BU of 8eih by Molmil
Cryo-EM structure of human DNMT3B homo-tetramer (form I)
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
8EIK
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BU of 8eik by Molmil
Cryo-EM structure of human DNMT3B homo-hexamer
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
8EIJ
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BU of 8eij by Molmil
Cryo-EM structure of human DNMT3B homo-trimer
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
8EII
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BU of 8eii by Molmil
Cryo-EM structure of human DNMT3B homo-tetramer (form II)
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
8TDR
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BU of 8tdr by Molmil
Crystal structure of the methyltransferase domain of DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-04
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
8TE3
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BU of 8te3 by Molmil
Crystal structure of the methyltransferase domain of R882C/R676K DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
8TE1
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BU of 8te1 by Molmil
Crystal structure of the methyltransferase domain of R882H/R676K DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
8TE4
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BU of 8te4 by Molmil
Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
3FHQ
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BU of 3fhq by Molmil
Structure of endo-beta-N-acetylglucosaminidase A
Descriptor: 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, Endo-beta-N-acetylglucosaminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose
Authors:Jie, Y, Li, L, Shaw, N, Li, Y, Song, J, Zhang, W, Xia, C, Zhang, R, Joachimiak, A, Zhang, H.-C, Wang, L.-X, Wang, P, Liu, Z.-J.
Deposit date:2008-12-10
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.452 Å)
Cite:Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A
Plos One, 4, 2009

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