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5M6A
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BU of 5m6a by Molmil
Crystal structure of cardiotoxic Bence-Jones light chain dimer H9
Descriptor: Bence-Jones light chain, GLYCEROL, PHOSPHATE ION
Authors:Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2016-10-24
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5M76
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BU of 5m76 by Molmil
Crystal structure of cardiotoxic Bence-Jones light chain dimer H10
Descriptor: BROMIDE ION, light chain dimer
Authors:Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2016-10-26
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5M6I
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BU of 5m6i by Molmil
Crystal structure of non-cardiotoxic Bence-Jones light chain dimer M8
Descriptor: SODIUM ION, light chain dimer
Authors:Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2016-10-25
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MUH
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BU of 5muh by Molmil
Crystal structure of an amyloidogenic light chain dimer H7
Descriptor: light chain dimer
Authors:Oberti, L, Rognoni, P, Russo, R, Maritan, M, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2017-01-13
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MVG
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BU of 5mvg by Molmil
Crystal structure of non-amyloidogenic light chain dimer M7
Descriptor: GLYCEROL, light chain dimer
Authors:Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2017-01-16
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MTL
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BU of 5mtl by Molmil
Crystal structure of an amyloidogenic light chain
Descriptor: light chain dimer,IGL@ protein,IGL@ protein
Authors:Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2017-01-10
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MUD
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BU of 5mud by Molmil
Crystal structure of an amyloidogenic light chain dimer H6
Descriptor: light chain dimer,IGL@ protein
Authors:Oberti, L, Bacarizo, J, Maritan, M, Rognoni, P, Bolognesi, M, Ricagno, S.
Deposit date:2017-01-13
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
6GRZ
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BU of 6grz by Molmil
Crystal structure of the light chain dimer mH6
Descriptor: GLYCEROL, mH6
Authors:Maritan, M, Ricagno, S, Ambrosetti, A, Oberti, L.
Deposit date:2018-06-13
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains
J.Mol.Biol., 2020
9FAB
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BU of 9fab by Molmil
Additional cryo-EM structure of cardiac amyloid AL59 - bent polymorph
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC)
Authors:Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S.
Deposit date:2024-05-10
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Additional cryo-EM structure of cardiac amyloid AL59 - bent polymorph
To be published
9FAC
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BU of 9fac by Molmil
Additional cryo-EM structure of cardiac amyloid AL59 - mixed polymorph
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC)
Authors:Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S.
Deposit date:2024-05-10
Release date:2024-08-14
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Nat Commun, 15, 2024
9FAA
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BU of 9faa by Molmil
Cryo-EM structure of cardiac collagen-associated amyloid AL59
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC)
Authors:Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S.
Deposit date:2024-05-10
Release date:2024-07-17
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Nat Commun, 15, 2024
6HUD
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BU of 6hud by Molmil
Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient.
Descriptor: Monoclonal immunoglobulin light chains (LC)
Authors:Paissoni, C, Camilloni, C.
Deposit date:2018-10-06
Release date:2019-03-27
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
Nat Commun, 10, 2019
8P89
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BU of 8p89 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody B5
Descriptor: CHLORIDE ION, Light chain H3, Nanobody B5
Authors:Broggini, L, Ricagno, S.
Deposit date:2023-05-31
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.187 Å)
Cite:Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023
8P88
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BU of 8p88 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody C4
Descriptor: CHLORIDE ION, Light Chain H3, Nanobody C4, ...
Authors:Broggini, L, Ricagno, S.
Deposit date:2023-05-31
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023

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