8FW2
| Cryo-EM structure of full-length human NLRC4 inflammasome with C11 symmetry | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S. | Deposit date: | 2023-01-20 | Release date: | 2024-01-03 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing. Nat.Struct.Mol.Biol., 31, 2024
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8FVU
| Cryo-EM structure of human Needle/NAIP/NLRC4 (R288A) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Baculoviral IAP repeat-containing protein 1, Lethal factor,Type III secretion system protein, ... | Authors: | Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S. | Deposit date: | 2023-01-19 | Release date: | 2024-01-03 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing. Nat.Struct.Mol.Biol., 31, 2024
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8FW9
| Cryo-EM structure of full-length human NLRC4 inflammasome with C12 symmetry | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S. | Deposit date: | 2023-01-20 | Release date: | 2024-01-03 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (4.46 Å) | Cite: | Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing. Nat.Struct.Mol.Biol., 31, 2024
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5YJE
| Crystal structure of HIRA(644-1017) | Descriptor: | Protein HIRA, SULFATE ION | Authors: | Sato, Y, Senda, M, Senda, T. | Deposit date: | 2017-10-10 | Release date: | 2018-06-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit Nat Commun, 9, 2018
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4ZBJ
| UBN1 peptide bound to H3.3/H4/Asf1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Histone H3, ... | Authors: | Marmorstein, R, Ricketts, M.D, Tang, Y. | Deposit date: | 2015-04-14 | Release date: | 2015-07-15 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.248 Å) | Cite: | Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex. Nat Commun, 6, 2015
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8GHN
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8GHA
| Hir3 Arm/Tail, Hir2 WD40, C-terminal Hpc2 | Descriptor: | Histone promoter control protein 2, Histone transcription regulator 3, Protein HIR2 | Authors: | Kim, H.J, Murakami, K. | Deposit date: | 2023-03-09 | Release date: | 2024-07-10 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Structure of the Hir histone chaperone complex. Mol.Cell, 84, 2024
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8GHM
| Hir1 WD40 domains and Asf1/H3/H4 | Descriptor: | Histone H3, Histone H4, Histone chaperone, ... | Authors: | Kim, H.J, Murakami, K. | Deposit date: | 2023-03-10 | Release date: | 2024-07-10 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Structure of the Hir histone chaperone complex. Mol.Cell, 84, 2024
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8GIX
| Chaetomium thermophilum Hir3 | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, Histone transcription regulator 3 homolog | Authors: | Szurgot, M.R, van Eeuwen, T, Kim, H.J, Marmorstein, R. | Deposit date: | 2023-03-14 | Release date: | 2024-07-10 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the Hir histone chaperone complex. Mol.Cell, 84, 2024
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8GHL
| the Hir complex core | Descriptor: | Histone transcription regulator 3, Protein HIR1, Protein HIR2 | Authors: | Kim, H.J, Murakami, K. | Deposit date: | 2023-03-10 | Release date: | 2024-07-17 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structure of the Hir histone chaperone complex. Mol.Cell, 84, 2024
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