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9CK0
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BU of 9ck0 by Molmil
Cocrystal of PPARg LBD and NFKBIB / IKBB peptide with agonist GW1929
Descriptor: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, NF-kappa-B inhibitor beta, Peroxisome proliferator-activated receptor gamma
Authors:Nemetchek, M.D, McClelland, L.J, Hughes, T.S.
Deposit date:2024-07-08
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cocrystal of PPARg LBD with NFKBIB / IKBB peptide containing N-anchor motif LxxLL and agonist GW1929
To Be Published
9CWN
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BU of 9cwn by Molmil
NRIP1_133 / RIP140 SxxLxxLL motif coregulator peptide with agonist GW1929 and PPARg LBD
Descriptor: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Nuclear receptor-interacting protein 1, Peroxisome proliferator-activated receptor gamma
Authors:Nemetchek, M.D, Voss, A.H, McClelland, L.J, Hughes, T.S.
Deposit date:2024-07-29
Release date:2024-08-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:NRIP1_133 / RIP140 SxxLxxLL motif coregulator peptide with agonist GW1929 and PPARg LBD
To Be Published
7RLE
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BU of 7rle by Molmil
Crystal structure of PPAR gamma in complex with CREB-binding protein and agonist GW1929
Descriptor: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CREB-binding protein, Peroxisome proliferator-activated receptor gamma
Authors:Nemetchek, M.D, Sprang, S.R, Hughes, T.S.
Deposit date:2021-07-23
Release date:2022-08-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A structural mechanism of nuclear receptor biased agonism.
Proc.Natl.Acad.Sci.USA, 119, 2022
6D94
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BU of 6d94 by Molmil
Crystal structure of PPAR gamma in complex with Mediator of RNA polymerase II transcription subunit 1
Descriptor: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Mediator of RNA polymerase II transcription subunit 1, Peroxisome proliferator-activated receptor gamma
Authors:Mou, T.C, Chrisman, I.M, Hughes, T.S, Sprang, S.R.
Deposit date:2018-04-27
Release date:2019-05-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural mechanism of nuclear receptor biased agonism.
Proc.Natl.Acad.Sci.USA, 119, 2022
6C1I
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BU of 6c1i by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907
Descriptor: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:Shang, J, Fuhrmann, J, Brust, R, Kojetin, D.J.
Deposit date:2018-01-04
Release date:2018-12-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma.
Nat Commun, 9, 2018
8TCO
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BU of 8tco by Molmil
HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CS2it1p2_F7K Fab heavy chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2023-07-02
Release date:2023-08-09
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023
8TEA
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BU of 8tea by Molmil
HCMV Pentamer in complex with CS2pt1p2_A10L Fab and CS3pt1p4_C1L Fab
Descriptor: CS2pt1p2_A10L Fab heavy chain, CS2pt1p2_A10L Fab light chain, CS3pt1p4_C1L Fab heavy chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2023-07-05
Release date:2023-08-09
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023

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건을2024-09-11부터공개중

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