6TLX
| Crystal structure of the unconventional kinetochore protein Perkinsela sp. KKT2a central domain | Descriptor: | Protein kinase, ZINC ION | Authors: | Marciano, G, Nerusheva, O, Ishii, M, Akiyoshi, B. | Deposit date: | 2019-12-03 | Release date: | 2019-12-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains. J.Cell Biol., 220, 2021
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6TLY
| Crystal structure of the unconventional kinetochore protein Bodo saltans KKT2 central domain | Descriptor: | CHLORIDE ION, Protein kinase, putative, ... | Authors: | Marciano, G, Nerusheva, O, Ishii, M, Akiyoshi, B. | Deposit date: | 2019-12-03 | Release date: | 2019-12-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains. J.Cell Biol., 220, 2021
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5E5B
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8A0K
| crystal structure of the kinetoplastid kinetochore protein Trypanosoma brucei KKT3 Divergent Polo-Box domain | Descriptor: | DI(HYDROXYETHYL)ETHER, Protein kinase, putative | Authors: | Ishii, M, Ludzia, P, Marciano, G, Allen, W, Nerusheva, O.O, Akiyoshi, B. | Deposit date: | 2022-05-27 | Release date: | 2022-06-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei. Mol.Biol.Cell, 33, 2022
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8A0J
| Crystal structure of the kinetoplastid kinetochore protein Trypanosoma congolense KKT2 divergent polo-box domain | Descriptor: | Uncharacterized protein TCIL3000_11_11110 | Authors: | Ishii, M, Ludzia, P, Marciano, G, Allen, W, Nerusheva, O, Akiyoshi, B. | Deposit date: | 2022-05-27 | Release date: | 2022-06-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei. Mol.Biol.Cell, 33, 2022
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6ZPK
| Crystal structure of the unconventional kinetochore protein Trypanosoma brucei KKT4 BRCT domain | Descriptor: | GLYCEROL, SULFATE ION, Trypanosoma brucei KKT4 463-645 | Authors: | Ludzia, P, Lowe, E.D, Marciano, G, Mohammed, S, Redfield, C, Akiyoshi, B. | Deposit date: | 2020-07-08 | Release date: | 2020-10-21 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein. Structure, 29, 2021
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6ZPJ
| Crystal structure of the unconventional kinetochore protein Leishmania mexicana KKT4 coiled coil domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, IMIDAZOLE, Leishmania mexicana KKT4 | Authors: | Ludzia, P, Lowe, E.D, Marciano, G, Mohammed, S, Redfield, C, Akiyoshi, B. | Deposit date: | 2020-07-08 | Release date: | 2020-10-21 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein. Structure, 29, 2021
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6ZPM
| Crystal structure of the unconventional kinetochore protein Trypanosoma cruzi KKT4 coiled coil domain | Descriptor: | THREONINE, Trypanosoma cruzi KKT4 117-218 | Authors: | Ludzia, P, Lowe, D.E, Marciano, G, Mohammed, S, Redfield, C, Akiyoshi, B. | Deposit date: | 2020-07-08 | Release date: | 2020-10-21 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein. Structure, 29, 2021
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7ZXW
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor | Descriptor: | 5-(morpholin-4-ylmethyl)quinolin-8-ol, CALCIUM ION, DIMETHYL SULFOXIDE, ... | Authors: | Le Cornu, J.D, Ibba, R, Roversi, P, Zitzmann, N. | Deposit date: | 2022-05-23 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.246 Å) | Cite: | Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint. Front Mol Biosci, 9, 2022
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6FSN
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 1) | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Roversi, P, Le Cornu, J.D, Hill, J, Alonzi, D.S, Zitzmann, N. | Deposit date: | 2018-02-19 | Release date: | 2019-03-20 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint. Front Mol Biosci, 2022
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7ZHB
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2) | Descriptor: | 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D. | Deposit date: | 2022-04-06 | Release date: | 2022-04-20 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint To Be Published
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7ZLE
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP | Descriptor: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D. | Deposit date: | 2022-04-14 | Release date: | 2022-06-22 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.823 Å) | Cite: | A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint To Be Published
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