4PDV
 
 | | Structure of K+ selective NaK mutant in barium and potassium | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, POTASSIUM ION, ... | | Authors: | Lam, Y, Zeng, W, Sauer, D.B, Jiang, Y. | | Deposit date: | 2014-04-22 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.821 Å) | | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter
To Be Published
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4PDR
 | | Crystal Structure of a K+ selective NaK mutant in Barium and Sodium | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, Potassium channel protein, ... | | Authors: | Lam, Y, Zeng, W, Sauer, D.B, Jiang, Y. | | Deposit date: | 2014-04-21 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter
To Be Published
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4PDL
 | | Structure of K+ selective NaK mutant in caesium | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, HEXANE, ... | | Authors: | Lam, Y, Zeng, W, Sauer, D.B, Jiang, Y. | | Deposit date: | 2014-04-19 | | Release date: | 2014-07-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter
To Be Published
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4PDM
 | | Crystal Structure of K+ selective NaK mutant in rubidium | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, RUBIDIUM ION | | Authors: | Lam, Y. | | Deposit date: | 2014-04-19 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter
To Be Published
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1QQT
 | | METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI | | Descriptor: | METHIONYL-TRNA SYNTHETASE, ZINC ION | | Authors: | Mechulam, Y, Schmitt, E, Maveyraud, L, Zelwer, C, Nureki, O, Yokoyama, S, Konno, M, Blanquet, S. | | Deposit date: | 1999-06-08 | | Release date: | 2000-01-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features.
J.Mol.Biol., 294, 1999
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3V11
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2QN6
 | | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 alpha subunit, ... | | Authors: | Mechulam, Y, Yatime, L, Blanquet, S, Schmitt, E. | | Deposit date: | 2007-07-18 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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4GX2
 | | GsuK channel bound to NAD | | Descriptor: | CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... | | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | | Deposit date: | 2012-09-03 | | Release date: | 2012-12-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
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4GX1
 | | Crystal structure of the GsuK bound to ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ... | | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | | Deposit date: | 2012-09-03 | | Release date: | 2012-12-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
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4GX0
 | | Crystal structure of the GsuK L97D mutant | | Descriptor: | CALCIUM ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | | Deposit date: | 2012-09-03 | | Release date: | 2012-12-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
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4GX5
 | | GsuK Channel | | Descriptor: | CALCIUM ION, POTASSIUM ION, TrkA domain protein, ... | | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | | Deposit date: | 2012-09-03 | | Release date: | 2012-12-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
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4GVL
 | | Crystal Structure of the GsuK RCK domain | | Descriptor: | ADENOSINE MONOPHOSPHATE, CALCIUM ION, TrkA domain protein, ... | | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | | Deposit date: | 2012-08-30 | | Release date: | 2012-12-26 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
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3O2A
 | | Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator | | Descriptor: | GLUTAMIC ACID, GLYCEROL, Glutamate receptor 2, ... | | Authors: | Maclean, J.K.F, Basten, S, Campbell, R.A, Cumming, I.A, Gillen, K.J, Gillespie, J, Jamieson, C, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Moir, E.M, Morrow, J.A, Papakosta, M, Rankovic, Z, Smith, L. | | Deposit date: | 2010-07-22 | | Release date: | 2010-09-15 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A novel series of positive modulators of the AMPA receptor: discovery and structure based hit-to-lead studies.
Bioorg.Med.Chem.Lett., 20, 2010
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1KK0
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1KK3
 | | Structure of the wild-type large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi complexed with GDP-Mg2+ | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Schmitt, E, Blanquet, S, Mechulam, Y. | | Deposit date: | 2001-12-06 | | Release date: | 2002-04-10 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
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6EZ3
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6FQ2
 | | Structure of minimal sequence for left -handed G-quadruplex formation | | Descriptor: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | | Deposit date: | 2018-02-13 | | Release date: | 2018-12-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew. Chem. Int. Ed. Engl., 58, 2019
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6GZ6
 | | Structure of a left-handed G-quadruplex | | Descriptor: | DNA (27-MER), POTASSIUM ION | | Authors: | Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T. | | Deposit date: | 2018-07-03 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.006 Å) | | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6Y3G
 | | Crystal structure of phenylalanine tRNA from Escherichia coli | | Descriptor: | CALCIUM ION, GLYCEROL, GUANIDINE, ... | | Authors: | Bourgeois, G, Mechulam, Y, Schmitt, E. | | Deposit date: | 2020-02-18 | | Release date: | 2020-12-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates.
Rna, 26, 2020
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5OCD
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6Q6R
 | | Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex | | Descriptor: | ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex | | Authors: | Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T. | | Deposit date: | 2018-12-11 | | Release date: | 2019-10-16 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex.
J.Struct.Biol., 209, 2020
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6Y4B
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6QJO
 | | DNA containing both right- and left-handed parallel-stranded G-quadruplexes | | Descriptor: | DNA (28-MER), POTASSIUM ION | | Authors: | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T. | | Deposit date: | 2019-01-24 | | Release date: | 2019-07-03 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
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5MLP
 | | Structure of CDPS from Rickettsiella grylli | | Descriptor: | Uncharacterized protein | | Authors: | Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E. | | Deposit date: | 2016-12-07 | | Release date: | 2018-05-02 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J.Struct.Biol., 203, 2018
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5MLQ
 | | Structure of CDPS from Nocardia brasiliensis | | Descriptor: | CDPS, CITRIC ACID | | Authors: | Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E. | | Deposit date: | 2016-12-07 | | Release date: | 2018-05-02 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J.Struct.Biol., 203, 2018
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