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1D31
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BU of 1d31 by Molmil
THE THREE-DIMENSIONAL STRUCTURES OF BULGE-CONTAINING DNA FRAGMENTS
Descriptor: DNA (5'-D(*CP*GP*CP*AP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Joshua-Tor, L, Frolow, F, Appella, E, Hope, H, Rabinovich, D, Sussman, J.L.
Deposit date:1991-04-25
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structures of bulge-containing DNA fragments.
J.Mol.Biol., 225, 1992
1GCB
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BU of 1gcb by Molmil
GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL)
Descriptor: GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ...
Authors:Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C.
Deposit date:1995-07-18
Release date:1995-10-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6.
Science, 269, 1995
1A6R
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BU of 1a6r by Molmil
GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A
Descriptor: GAL6, SULFATE ION
Authors:Joshua-Tor, L, Zheng, W, Johnston, S.A.
Deposit date:1998-02-27
Release date:1998-10-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.
Cell(Cambridge,Mass.), 93, 1998
3GCB
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BU of 3gcb by Molmil
GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454
Descriptor: GAL6, GLYCEROL, SULFATE ION
Authors:Joshua-Tor, L, Zheng, W, Johnston, S.A.
Deposit date:1998-02-27
Release date:1998-10-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.
Cell(Cambridge,Mass.), 93, 1998
2E00
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BU of 2e00 by Molmil
Crystal structure of N392L mutant of yeast bleomycin hydrolase
Descriptor: Cysteine proteinase 1
Authors:O'Farrell, P.A, Joshua-Tor, L.
Deposit date:2006-10-01
Release date:2007-11-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007
6X46
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BU of 6x46 by Molmil
NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains)
Descriptor: Gametocyte-specific factor 1, ZINC ION
Authors:Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L.
Deposit date:2020-05-22
Release date:2021-03-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons.
Cell Rep, 34, 2021
1KQJ
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BU of 1kqj by Molmil
Crystal Structure of a Mutant of MutY Catalytic Domain
Descriptor: A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L.
Deposit date:2002-01-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002
1KOU
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BU of 1kou by Molmil
Crystal Structure of the Photoactive Yellow Protein Reconstituted with Caffeic Acid at 1.16 A Resolution
Descriptor: CAFFEIC ACID, N-BUTANE, PHOTOACTIVE YELLOW PROTEIN
Authors:van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2001-12-22
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1KSY
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Crystal Structures of Two Intermediates in the Assembly of the Papillomavirus Replication Initiation Complex
Descriptor: E1 Recognition Sequence, Strand 1, Strand 2, ...
Authors:Enemark, E.J, Stenlund, A, Joshua-Tor, L.
Deposit date:2002-01-14
Release date:2002-03-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.
EMBO J., 21, 2002
1KSX
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Crystal Structures of Two Intermediates in the Assembly of the Papillomavirus Replication Initiation Complex
Descriptor: E1 Recognition Sequence, REPLICATION PROTEIN E1
Authors:Enemark, E.J, Stenlund, A, Joshua-Tor, L.
Deposit date:2002-01-14
Release date:2002-03-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.
EMBO J., 21, 2002
6OTF
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BU of 6otf by Molmil
Symmetric reconstruction of human norovirus GII.2 Snow Mountain Virus Strain VLP in T=3 symmetry
Descriptor: Viral protein 1, ZINC ION
Authors:Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
Deposit date:2019-05-03
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
7UX9
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BU of 7ux9 by Molmil
Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA)
Descriptor: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ...
Authors:Ipsaro, J.J, Adams, D.W, Joshua-Tor, L.
Deposit date:2022-05-05
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Cell, 186, 2023
7JPP
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BU of 7jpp by Molmil
ORC-O2WH: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC1 AAA+ domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
4O9D
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BU of 4o9d by Molmil
Structure of Dos1 propeller
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Rik1-associated factor 1
Authors:Kuscu, C, Schalch, T, Joshua-Tor, L.
Deposit date:2014-01-02
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PMW
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BU of 4pmw by Molmil
Structure of mouse Dis3L2 in complex with oligoU RNA substrate
Descriptor: DIS3-like exonuclease 2, MAGNESIUM ION, U-U-U-U-U-U-U-U-U-U-U-U-U-U
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2014-05-22
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.
Nature, 514, 2014
4KRE
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BU of 4kre by Molmil
Structure of Human Argonaute-1 bound to endogenous Sf9 RNA
Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*A*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
4KRF
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BU of 4krf by Molmil
Structure of Human Argonaute-1 let-7 complex
Descriptor: Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
8E29
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BU of 8e29 by Molmil
Human Dis3L2 in complex with hairpin C-U12
Descriptor: DIS3-like exonuclease 2, RNA hairpin C-U12
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
8E27
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BU of 8e27 by Molmil
RNA-free Human Dis3L2
Descriptor: DIS3-like exonuclease 2
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
8E28
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BU of 8e28 by Molmil
Human Dis3L2 in complex with hairpin A-GCU14
Descriptor: DIS3-like exonuclease 2, RNA hairpin A-GCU14
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
8E2A
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BU of 8e2a by Molmil
Human Dis3L2 in complex with hairpin D-U7
Descriptor: DIS3-like exonuclease 2, RNA hairpin D-U7
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
4X4T
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BU of 4x4t by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACCA
Descriptor: CCA-adding enzyme, DI(HYDROXYETHYL)ETHER, G70A tRNA minihelix ending in CCACCA, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
3G7L
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BU of 3g7l by Molmil
Chromodomain of Chp1 in complex with Histone H3K9me3 peptide
Descriptor: ACETIC ACID, Chromo domain-containing protein 1, Histone H3.1/H3.2, ...
Authors:Schalch, T, Joshua-Tor, L.
Deposit date:2009-02-10
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin
Mol.Cell, 34, 2009
4X4Q
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BU of 4x4q by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCAC and CTP
Descriptor: CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
4X4P
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BU of 4x4p by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCAC
Descriptor: CCA-adding enzyme, G70A tRNA minihelix ending in CCAC, SULFATE ION
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015

 

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