1MCT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mct by Molmil](/molmil-images/mine/1mct) | THE REFINED 1.6 ANGSTROMS RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PORCINE BETA-TRYPSIN AND MCTI-A, A TRYPSIN INHIBITOR OF SQUASH FAMILY | Descriptor: | BETA-TRYPSIN, CALCIUM ION, TRYPSIN INHIBITOR A | Authors: | Huang, Q, Liu, S, Tang, Y. | Deposit date: | 1992-10-24 | Release date: | 1994-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Refined 1.6 A resolution crystal structure of the complex formed between porcine beta-trypsin and MCTI-A, a trypsin inhibitor of the squash family. Detailed comparison with bovine beta-trypsin and its complex. J.Mol.Biol., 229, 1993
|
|
1MRJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mrj by Molmil](/molmil-images/mine/1mrj) | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | Descriptor: | ADENOSINE, ALPHA-TRICHOSANTHIN | Authors: | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | Deposit date: | 1994-07-01 | Release date: | 1995-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins. Biochem.J., 309, 1995
|
|
5D3O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5d3o by Molmil](/molmil-images/mine/5d3o) | |
8DZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dzt by Molmil](/molmil-images/mine/8dzt) | Crystal structure of human Sar1aH79G mutant | Descriptor: | CALCIUM ION, GTP-binding protein SAR1a, GUANOSINE-5',3'-TETRAPHOSPHATE, ... | Authors: | Huang, Q. | Deposit date: | 2022-08-08 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8E0A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e0a by Molmil](/molmil-images/mine/8e0a) | Crystal structure of human Sar1b | Descriptor: | GTP-binding protein SAR1b, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | Authors: | Huang, Q. | Deposit date: | 2022-08-08 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8E0D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e0d by Molmil](/molmil-images/mine/8e0d) | Crystal structure of human Sar1bE140D | Descriptor: | GTP-binding protein SAR1b, GUANOSINE-5',3'-TETRAPHOSPHATE | Authors: | Huang, Q. | Deposit date: | 2022-08-08 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8E0H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e0h by Molmil](/molmil-images/mine/8e0h) | Crystal structure of human Sar1aD104/D140A double mutant | Descriptor: | GTP-binding protein SAR1a, GUANOSINE-5',3'-TETRAPHOSPHATE | Authors: | Huang, Q. | Deposit date: | 2022-08-09 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8DZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dzo by Molmil](/molmil-images/mine/8dzo) | Crystal structure of human Sar1T39N mutant | Descriptor: | CALCIUM ION, GTP-binding protein SAR1a, GUANOSINE-5',3'-TETRAPHOSPHATE, ... | Authors: | Huang, Q. | Deposit date: | 2022-08-08 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8E0B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e0b by Molmil](/molmil-images/mine/8e0b) | Crystal structure of human Sar1bT39N | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Sar1bT39N | Authors: | Huang, Q. | Deposit date: | 2022-08-08 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.212 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8E0C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e0c by Molmil](/molmil-images/mine/8e0c) | Crystal structure of human Sar1bH79G | Descriptor: | GTP-binding protein SAR1b, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Huang, Q. | Deposit date: | 2022-08-08 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.993 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8DZN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dzn by Molmil](/molmil-images/mine/8dzn) | Crystal structure of human Sar1a in complex with GDP | Descriptor: | GTP-binding protein SAR1a, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | Authors: | Huang, Q. | Deposit date: | 2022-08-08 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.107 Å) | Cite: | The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
|
|
8DZM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dzm by Molmil](/molmil-images/mine/8dzm) | |
2FM5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fm5 by Molmil](/molmil-images/mine/2fm5) | Crystal structure of PDE4D2 in complex with inhibitor L-869299 | Descriptor: | (R)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHYL)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ... | Authors: | Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H. | Deposit date: | 2006-01-07 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase J.Med.Chem., 49, 2006
|
|
2FM0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fm0 by Molmil](/molmil-images/mine/2fm0) | Crystal structure of PDE4D in complex with L-869298 | Descriptor: | (S)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHY L)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ... | Authors: | Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H. | Deposit date: | 2006-01-06 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase J.Med.Chem., 49, 2006
|
|
3BI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bi5 by Molmil](/molmil-images/mine/3bi5) | |
3BI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bi4 by Molmil](/molmil-images/mine/3bi4) | Crystal structures of fms1 in complex with its inhibitors | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, N-[(1E,2Z)-but-2-en-1-ylidene]-N'-[(2E)-but-2-en-1-ylidene]butane-1,4-diamine, Polyamine oxidase FMS1 | Authors: | Huang, Q, Hao, Q. | Deposit date: | 2007-11-29 | Release date: | 2008-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of fms1 in complex with its inhibitors To be Published
|
|
3BI2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bi2 by Molmil](/molmil-images/mine/3bi2) | |
3BNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bnm by Molmil](/molmil-images/mine/3bnm) | Crystal structure of polyamine oxidase FMS1 from Saccharomyces cerevisiae in complex with bis-(3R,3'R)-methylated spermine | Descriptor: | (3R,3'R)-N~1~,N~1~'-butane-1,4-diyldibutane-1,3-diamine, FLAVIN-ADENINE DINUCLEOTIDE, Polyamine oxidase FMS1 | Authors: | Huang, Q, Hao, Q. | Deposit date: | 2007-12-14 | Release date: | 2008-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of the substrate stereospecificity of FMS1. To Be Published
|
|
3BNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bnu by Molmil](/molmil-images/mine/3bnu) | Crystal structure of polyamine oxidase FMS1 from Saccharomyces cerevisiae in complex with bis-(3S,3'S)-methylated spermine | Descriptor: | (3S,3'S)-N~1~,N~1~'-butane-1,4-diyldibutane-1,3-diamine, FLAVIN-ADENINE DINUCLEOTIDE, Polyamine oxidase FMS1 | Authors: | Huang, Q, Hao, Q. | Deposit date: | 2007-12-14 | Release date: | 2008-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of the substrate stereospecificity of FMS1. To Be Published
|
|
1Z6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z6l by Molmil](/molmil-images/mine/1z6l) | |
1RSG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rsg by Molmil](/molmil-images/mine/1rsg) | |
1YY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yy5 by Molmil](/molmil-images/mine/1yy5) | |
1XPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xpq by Molmil](/molmil-images/mine/1xpq) | Crystal structure of fms1, a polyamine oxidase from yeast | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Polyamine oxidase FMS1, SPERMINE | Authors: | Huang, Q, Liu, Q, Hao, Q. | Deposit date: | 2004-10-09 | Release date: | 2005-04-26 | Last modified: | 2021-12-08 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystal structures of Fms1 and its complex with spermine reveal substrate specificity. J.Mol.Biol., 348, 2005
|
|
6UJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ujg by Molmil](/molmil-images/mine/6ujg) | Crystal structure of human GAC in complex with inhibitor UPGL00012 | Descriptor: | Glutaminase kidney isoform, mitochondrial, N-{5-[(3S)-3-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]amino}pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | Authors: | Huang, Q, Cerione, R.A. | Deposit date: | 2019-10-03 | Release date: | 2020-10-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human GAC in complex with inhibitor UPGL00012 To Be Published
|
|
6UME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ume by Molmil](/molmil-images/mine/6ume) | Crystal structure of human GAC in complex with inhibitor UPGL00012 | Descriptor: | 2-(pyridin-3-yl)-N-(5-{4-[(5-{[(pyridin-3-yl)acetyl]amino}-1,3,4-thiadiazol-2-yl)amino]piperidin-1-yl}-1,3,4-thiadiazol-2-yl)acetamide, Glutaminase kidney isoform, mitochondrial | Authors: | Huang, Q, Cerione, R.A. | Deposit date: | 2019-10-09 | Release date: | 2020-10-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human GAC in complex with inhibitor UPGL00012 To Be Published
|
|