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4AAG
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BU of 4aag by Molmil
Crystal structure of the mutant D75N I-CreI in complex with its wild- type target in presence of Ca at the active site (The four central bases, 2NN region, are composed by GTAC from 5' to 3')
Descriptor: 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*CP *GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', CALCIUM ION, DNA ENDONUCLEASE I-CREI
Authors:Molina, R, Redondo, P, Stella, S, Marenchino, M, D'Abramo, M, Gervasio, F, Epinat, J.C, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
Deposit date:2011-12-01
Release date:2012-05-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
Nucleic Acids Res., 40, 2012
3OEZ
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BU of 3oez by Molmil
crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain complexed with imatinib
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, ACETATE ION, GLYCEROL, ...
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2010-08-13
Release date:2011-08-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation
To be Published
3OF0
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BU of 3of0 by Molmil
crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain
Descriptor: Proto-oncogene tyrosine-protein kinase Src
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2010-08-13
Release date:2011-08-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation
To be Published
3QLG
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BU of 3qlg by Molmil
Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with dasatinib
Descriptor: N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase Src
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2011-02-02
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation
To be Published
3QLF
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BU of 3qlf by Molmil
Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5
Descriptor: 1-{4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src
Authors:Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:2011-02-02
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation
To be Published

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