1FZC
 
 | | CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH TWO DIFFERENT BOUND LIGANDS | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Everse, S.J, Spraggon, G, Veerapandian, L, Riley, M, Doolittle, R.F. | | Deposit date: | 1998-05-19 | | Release date: | 1998-10-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of fragment double-D from human fibrin with two different bound ligands.
Biochemistry, 37, 1998
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1FZF
 | | CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN | | Authors: | Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F. | | Deposit date: | 1998-12-28 | | Release date: | 1999-06-08 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
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1FZE
 | | CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN | | Authors: | Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F. | | Deposit date: | 1998-12-23 | | Release date: | 1999-06-08 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
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1FZG
 | | CRYSTAL STRUCTURE OF FRAGMENT D FROM HUMAN FIBRINOGEN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN | | Authors: | Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F. | | Deposit date: | 1999-01-01 | | Release date: | 1999-06-08 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
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3MC2
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2NVK
 | | Crystal Structure of Thioredoxin Reductase from Drosophila melanogaster | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin Reductase | | Authors: | Eckenroth, B.E, Rould, M.A, Hondal, R.J, Everse, S.J. | | Deposit date: | 2006-11-13 | | Release date: | 2007-04-24 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Biochemical Studies Reveal Differences in the Catalytic Mechanisms of Mammalian and Drosophila melanogaster Thioredoxin Reductases.
Biochemistry, 46, 2007
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3S9M
 | | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | | Authors: | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | | Deposit date: | 2011-06-01 | | Release date: | 2011-08-10 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3S9N
 | | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | | Authors: | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | | Deposit date: | 2011-06-01 | | Release date: | 2011-08-10 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3DH9
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3DGZ
 | | Crystal Structure of Mouse Mitochondrial Thioredoxin Reductase, C-terminal 3-residue truncation | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 2, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | | Authors: | Eckenroth, B.E, Hondal, R.J, Everse, S.J. | | Deposit date: | 2008-06-16 | | Release date: | 2009-06-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal Structure of Mouse Mitochondrial Thioredoxin Reductase, C-terminal 3-residue truncation
To be Published
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3FGS
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3DGH
 | | Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Thioredoxin reductase 1, ... | | Authors: | Eckenroth, B.E, Hondal, R.J, Everse, S.J. | | Deposit date: | 2008-06-13 | | Release date: | 2009-06-16 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.745 Å) | | Cite: | Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation
To be Published
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3S9L
 | | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | | Authors: | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | | Deposit date: | 2011-06-01 | | Release date: | 2011-08-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.22 Å) | | Cite: | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2HAV
 | | Apo-Human Serum Transferrin (Glycosylated) | | Descriptor: | CITRIC ACID, GLYCEROL, Serotransferrin | | Authors: | Wally, J, Everse, S.J. | | Deposit date: | 2006-06-13 | | Release date: | 2006-06-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Crystal Structure of Iron-free Human Serum Transferrin Provides Insight into Inter-lobe Communication and Receptor Binding.
J.Biol.Chem., 281, 2006
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2HAU
 | | Apo-Human Serum Transferrin (Non-Glycosylated) | | Descriptor: | CITRIC ACID, GLYCEROL, Serotransferrin | | Authors: | Wally, J, Everse, S.J. | | Deposit date: | 2006-06-13 | | Release date: | 2006-06-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Crystal Structure of Iron-free Human Serum Transferrin Provides Insight into Inter-lobe Communication and Receptor Binding.
J.Biol.Chem., 281, 2006
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1SDD
 | | Crystal Structure of Bovine Factor Vai | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ... | | Authors: | Adams, T.E, Hockin, M.F, Mann, K.G, Everse, S.J. | | Deposit date: | 2004-02-13 | | Release date: | 2004-06-29 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1RYO
 | | Human serum transferrin, N-lobe bound with oxalate | | Descriptor: | FE (III) ION, OXALATE ION, Serotransferrin | | Authors: | Halbrooks, P.J, Mason, A.B, Adams, T.E, Briggs, S.K, Everse, S.J. | | Deposit date: | 2003-12-22 | | Release date: | 2004-05-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The oxalate effect on release of iron from human serum transferrin explained.
J.Mol.Biol., 339, 2004
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1N7X
 | | HUMAN SERUM TRANSFERRIN, N-LOBE Y45E MUTANT | | Descriptor: | CARBONATE ION, FE (III) ION, Serotransferrin | | Authors: | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | | Deposit date: | 2002-11-18 | | Release date: | 2003-03-18 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
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1N7W
 | | Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant | | Descriptor: | CARBONATE ION, FE (III) ION, Serotransferrin | | Authors: | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, MacGillivray, R.T, Everse, S.J. | | Deposit date: | 2002-11-18 | | Release date: | 2003-03-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Position of Arginine 124 Controls the Rate of Iron Release from the N-lobe of Human Serum Transferrin. A Structural Study
J.Biol.Chem., 278, 2003
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1N84
 | | HUMAN SERUM TRANSFERRIN, N-LOBE | | Descriptor: | CARBONATE ION, FE (III) ION, Serotransferrin | | Authors: | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | | Deposit date: | 2002-11-19 | | Release date: | 2003-03-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
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1LWU
 | | Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Yang, Z, Spraggon, G, Pandi, L, Everse, S.J, Riley, M, Doolittle, R.F. | | Deposit date: | 2002-06-03 | | Release date: | 2002-08-23 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.
Biochemistry, 41, 2002
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1FZD
 | | STRUCTURE OF RECOMBINANT ALPHAEC DOMAIN FROM HUMAN FIBRINOGEN-420 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Spraggon, G, Applegate, D, Everse, S.J, Zhang, J.-Z, Veerapandian, L, Redman, C, Doolittle, R.F, Grieninger, G. | | Deposit date: | 1998-06-22 | | Release date: | 1998-08-19 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of a recombinant alphaEC domain from human fibrinogen-420.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1FZA
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1FZB
 | | CRYSTAL STRUCTURE OF CROSSLINKED FRAGMENT D | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | | Authors: | Spraggon, G, Everse, S.J, Doolittle, R.F. | | Deposit date: | 1997-08-05 | | Release date: | 1997-12-03 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.
Nature, 389, 1997
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1N86
 | | Crystal structure of human D-dimer from cross-linked fibrin complexed with GPR and GHRPLDK peptide ligands. | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Fibrin alpha/alpha-E chain, ... | | Authors: | Yang, Z, Pandi, L, Doolittle, R.F. | | Deposit date: | 2002-11-19 | | Release date: | 2003-01-07 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
Biochemistry, 41, 2002
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