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6EM9
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BU of 6em9 by Molmil
S.aureus ClpC resting state, asymmetric map
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpC
Authors:Carroni, M, Mogk, A, Bukau, B, Franke, K.
Deposit date:2017-10-01
Release date:2017-12-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
6EMW
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BU of 6emw by Molmil
Structure of S.aureus ClpC in complex with MecA
Descriptor: ATP-dependent Clp protease ATP-binding subunit, ATP-dependent Clp protease ATP-binding subunit ClpC, Adapter protein MecA, ...
Authors:Carroni, M, Mogk, A, Bukau, B, Franke, K.
Deposit date:2017-10-03
Release date:2017-12-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
6EM8
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BU of 6em8 by Molmil
S.aureus ClpC resting state, C2 symmetrised
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpC
Authors:Carroni, M, Mogk, A.
Deposit date:2017-10-01
Release date:2017-12-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
4YZS
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BU of 4yzs by Molmil
Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 3, TUNGSTEN ION
Authors:Carrara, M, Prischi, F, Ali, M.M.U.
Deposit date:2015-03-25
Release date:2015-05-13
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Embo J., 34, 2015
4YZY
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BU of 4yzy by Molmil
Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 3
Authors:Carrara, M, Prischi, F, Ali, M.M.U.
Deposit date:2015-03-25
Release date:2015-05-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Embo J., 34, 2015
4D2U
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BU of 4d2u by Molmil
Negative-stain electron microscopy of E. coli ClpB (BAP form bound to ClpP)
Descriptor: CHAPERONE PROTEIN CLPB
Authors:Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
Deposit date:2014-05-13
Release date:2014-06-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014
4D2Q
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BU of 4d2q by Molmil
Negative-stain electron microscopy of E. coli ClpB mutant E432A (BAP form bound to ClpP)
Descriptor: CLPB
Authors:Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
Deposit date:2014-05-12
Release date:2014-06-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014
4D2X
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BU of 4d2x by Molmil
Negative-stain electron microscopy of E. coli ClpB of Y503D hyperactive mutant (BAP form bound to ClpP)
Descriptor: CHAPERONE PROTEIN CLPB
Authors:Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
Deposit date:2014-05-13
Release date:2014-06-04
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014
8PYQ
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BU of 8pyq by Molmil
10 micrometer HEWL crystals solved at room-temperature using fixed-target serial crystallography.
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Mason, T.J, Carrillo, M, Beale, J.H, Padeste, C.
Deposit date:2023-07-25
Release date:2023-08-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs.
Iucrj, 10, 2023
8PYO
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BU of 8pyo by Molmil
5 micrometer HEWL crystals solved at room-temperature using fixed-target serial crystallography.
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Mason, T.J, Carrillo, M, Beale, J.H, Padeste, C.
Deposit date:2023-07-25
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs.
Iucrj, 10, 2023
8PYP
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BU of 8pyp by Molmil
25 micrometer HEWL crystals solved at room-temperature using fixed-target serial crystallography.
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Mason, T.J, Carrillo, M, Beale, J.H, Padeste, C.
Deposit date:2023-07-25
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs.
Iucrj, 10, 2023
7QVK
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BU of 7qvk by Molmil
NM-02 in complex with HER2-ECD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NM-02, Receptor tyrosine-protein kinase erbB-2, ...
Authors:Cowan, R, Hall, G, Carr, M.
Deposit date:2022-01-21
Release date:2023-02-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool.
Plos One, 18, 2023
1POS
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BU of 1pos by Molmil
CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOUND IN A LARGE FAMILY OF PUTATIVE GROWTH FACTORS
Descriptor: PORCINE PANCREATIC SPASMOLYTIC POLYPEPTIDE
Authors:De, A, Brown, D, Gorman, M, Carr, M, Sanderson, M.R, Freemont, P.S.
Deposit date:1993-10-08
Release date:1994-01-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors.
Proc.Natl.Acad.Sci.USA, 91, 1994
6ZGK
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BU of 6zgk by Molmil
GLIC pentameric ligand-gated ion channel, pH 3
Descriptor: Proton-gated ion channel
Authors:Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E.
Deposit date:2020-06-18
Release date:2021-05-26
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations.
Life Sci Alliance, 4, 2021
6ZGD
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BU of 6zgd by Molmil
GLIC pentameric ligand-gated ion channel, pH 7
Descriptor: Proton-gated ion channel
Authors:Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E.
Deposit date:2020-06-18
Release date:2021-05-26
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations.
Life Sci Alliance, 4, 2021
6ZGJ
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BU of 6zgj by Molmil
GLIC pentameric ligand-gated ion channel, pH 5
Descriptor: Proton-gated ion channel
Authors:Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E.
Deposit date:2020-06-18
Release date:2021-05-26
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations.
Life Sci Alliance, 4, 2021
6ZJK
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BU of 6zjk by Molmil
Ribonucleotide reductase R2 subunit from Clostridium botulinum
Descriptor: FE (III) ION, GLYCEROL, Ribonucleoside-diphosphate reductase subunit beta
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2020-06-29
Release date:2020-09-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site.
J.Biol.Chem., 295, 2020
7PFP
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BU of 7pfp by Molmil
Full-length cryo-EM structure of the native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
Deposit date:2021-08-11
Release date:2022-03-16
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
7Q3N
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BU of 7q3n by Molmil
Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ...
Authors:Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
Deposit date:2021-10-28
Release date:2022-03-16
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
8BYP
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BU of 8byp by Molmil
Botulinum neurotoxin serotype X in complex with NTNH/X
Descriptor: Botulinum neurotoxin type X, NTNH/X
Authors:Martinez-Carranza, M, Skerlova, J, Stenmark, P.
Deposit date:2022-12-15
Release date:2023-02-08
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structure and activity of botulinum neurotoxin X.
Biorxiv, 2023
8C5Y
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BU of 8c5y by Molmil
RPA tetrameric supercomplex from Pyrococcus abyssi
Descriptor: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
Authors:Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
Deposit date:2023-01-10
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8C5Z
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BU of 8c5z by Molmil
RPA tetrameric supercomplex with AROD-OB-1
Descriptor: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
Authors:Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
Deposit date:2023-01-10
Release date:2023-05-10
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8C5H
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BU of 8c5h by Molmil
NbSyt1 anti-(rat Synaptotagmin-1) nanobody bound to target cytosolic domain of Synaptotagmin-1
Descriptor: CALCIUM ION, GLYCEROL, NbSyt1 nanobody, ...
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2023-01-09
Release date:2023-08-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A Versatile Synaptotagmin-1 Nanobody Provides Perturbation-Free Live Synaptic Imaging And Low Linkage-Error in Super-Resolution Microscopy.
Small Methods, 7, 2023
6TQL
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BU of 6tql by Molmil
Cryo-EM of elastase-treated human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L.
Deposit date:2019-12-16
Release date:2020-11-04
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Embo J., 39, 2020
6TQK
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BU of 6tqk by Molmil
Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ...
Authors:Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L.
Deposit date:2019-12-16
Release date:2020-11-04
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Embo J., 39, 2020

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