5EU5
 
 | | HLA Class I antigen | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | | Deposit date: | 2015-11-18 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
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5EU6
 | | HLA Class I antigen | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | | Deposit date: | 2015-11-18 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
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5EU4
 | | HLA Class I antigen | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | | Deposit date: | 2015-11-18 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
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5EU3
 | | HLA Class I antigen | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | | Deposit date: | 2015-11-18 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
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1Q91
 | | Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor DPB-T | | Descriptor: | (S)-1-[2'-DEOXY-3',5'-O-(1-PHOSPHONO)BENZYLIDENE-B-D-THREO-PENTOFURANOSYL]THYMINE, 5(3)-deoxyribonucleotidase, MAGNESIUM ION, ... | | Authors: | Rinaldo-Matthis, A, Rampazzo, C, Balzarini, J, Reichard, P, Bianchi, V, Nordlund, P. | | Deposit date: | 2003-08-22 | | Release date: | 2004-04-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors
Mol.Pharmacol., 65, 2004
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1Q92
 | | Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor PMcP-U | | Descriptor: | 5(3)-deoxyribonucleotidase, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Rinaldo-Matthis, A, Rampazzo, C, Balzarini, J, Reichard, P, Bianchi, V, Nordlund, P. | | Deposit date: | 2003-08-22 | | Release date: | 2004-04-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors
Mol.Pharmacol., 65, 2004
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2JAR
 | | Crystal structure of D12N variant of mouse cytosolic 5'(3')- deoxyribonucleotidase (cdN) in complex with deoxyuridine 5'- monophosphate | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5'(3')-DEOXYRIBONUCLEOTIDASE, MAGNESIUM ION | | Authors: | Wallden, K, Ruzzenente, B, Bianchi, V, Nordlund, P. | | Deposit date: | 2006-11-30 | | Release date: | 2007-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues.
Biochemistry, 46, 2007
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2JAU
 | | Crystal structure of D41N variant of human mitochondrial 5'(3')- deoxyribonucleotidase (mdN) in complex with 3'-azidothymidine 5'- monophosphate | | Descriptor: | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, 5'(3')-DEOXYRIBONUCLEOTIDASE, MAGNESIUM ION, ... | | Authors: | Wallden, K, Ruzzenente, B, Bianchi, V, Nordlund, P. | | Deposit date: | 2006-11-30 | | Release date: | 2007-12-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues.
Biochemistry, 46, 2007
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2JAW
 | | Crystal structure of D41N variant of human mitochondrial 5'(3')- deoxyribonucleotidase (mdN) in complex with 5-bromovinyldeoxyuridine 5'-monophosphate | | Descriptor: | (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5'(3')-DEOXYRIBONUCLEOTIDASE, MAGNESIUM ION | | Authors: | Wallden, K, Ruzzenente, B, Bianchi, V, Nordlund, P. | | Deposit date: | 2006-11-30 | | Release date: | 2007-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues.
Biochemistry, 46, 2007
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1MH9
 | | Crystal Structure Analysis of deoxyribonucleotidase | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, deoxyribonucleotidase | | Authors: | Rinaldo-Matthis, A, Rampazzo, C, Reichard, P, Bianchi, V, Nordlund, P. | | Deposit date: | 2002-08-19 | | Release date: | 2002-10-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of a human mitochondrial deoxyribonucleotidase.
Nat.Struct.Biol., 9, 2002
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1FDR
 | | FLAVODOXIN REDUCTASE FROM E. COLI | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVODOXIN REDUCTASE | | Authors: | Ingelman, M, Bianchi, V, Eklund, H. | | Deposit date: | 1997-03-06 | | Release date: | 1997-09-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The three-dimensional structure of flavodoxin reductase from Escherichia coli at 1.7 A resolution.
J.Mol.Biol., 268, 1997
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1Z4Q
 | | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with 2',3'-dideoxy-2',3-didehydrothymidine 5'-monophosphate (d4T-MP) | | Descriptor: | 5'(3')-deoxyribonucleotidase, MAGNESIUM ION, [(5R)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-2,5-DIHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE | | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | | Deposit date: | 2005-03-16 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
STRUCTURE, 13, 2005
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1Z4I
 | | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with deoxyribouridine 5'-monophosphate | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5'(3')-deoxyribonucleotidase, GLYCEROL, ... | | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | | Deposit date: | 2005-03-16 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
STRUCTURE, 13, 2005
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1Z4J
 | | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with uridine 2'-monophosphate | | Descriptor: | 5'(3')-deoxyribonucleotidase, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | | Deposit date: | 2005-03-16 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
STRUCTURE, 13, 2005
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1Z4L
 | | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with thymidine 5'-monophosphate | | Descriptor: | 5'(3')-deoxyribonucleotidase, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE | | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | | Deposit date: | 2005-03-16 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
STRUCTURE, 13, 2005
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1Z4K
 | | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with thymidine 3'-monophosphate | | Descriptor: | 5'(3')-deoxyribonucleotidase, MAGNESIUM ION, THYMIDINE-3'-PHOSPHATE | | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | | Deposit date: | 2005-03-16 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
STRUCTURE, 13, 2005
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1Z4P
 | | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with deoxyriboguanosine 5'-monophosphate | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, 5'(3')-deoxyribonucleotidase, MAGNESIUM ION | | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | | Deposit date: | 2005-03-16 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
STRUCTURE, 13, 2005
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1Z4M
 | | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with uridine 5'-monophosphate | | Descriptor: | 5'(3')-deoxyribonucleotidase, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | | Deposit date: | 2005-03-16 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
STRUCTURE, 13, 2005
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2JAO
 | | Crystal structure of D12N variant of mouse cytosolic 5'(3')- deoxyribonucleotidase (cdN) in complex with deoxyguanosine 5'- monophosphate | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, 5'(3')-DEOXYRIBONUCLEOTIDASE, GLYCEROL, ... | | Authors: | Wallden, K, Ruzzenente, B, Bianchi, V, Nordlund, P. | | Deposit date: | 2006-11-29 | | Release date: | 2007-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues.
Biochemistry, 46, 2007
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7ZUC
 | | Human Major Histocompatibility Complex A2 allele presenting LLLGIGILV | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-LEU-LEU-GLY-ILE-GLY-ILE-LEU-VAL, ... | | Authors: | Rizkallah, P.J, Wall, A, Sewell, A.K, Fuller, A. | | Deposit date: | 2022-05-12 | | Release date: | 2023-05-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
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6FR3
 | | 003 TCR Study of CDR Loop Flexibility | | Descriptor: | 003 TCR Alpha Chain, 003 TCR Beta Chain, 1,2-ETHANEDIOL, ... | | Authors: | Rizkallah, P.J, Cole, D.K. | | Deposit date: | 2018-02-15 | | Release date: | 2018-04-18 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
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6FRC
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6FR5
 | | HA1.7 TCR Study of CDR Loop Flexibility | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Cole, D.K. | | Deposit date: | 2018-02-15 | | Release date: | 2018-04-18 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
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6FR8
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6FUM
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