1Z4Q

Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with 2',3'-dideoxy-2',3-didehydrothymidine 5'-monophosphate (d4T-MP)

Summary for 1Z4Q

Entry DOI	10.2210/pdb1z4q/pdb
Related	1Z4I 1Z4J 1Z4K 1Z4L 1Z4M 1Z4P
Descriptor	5'(3')-deoxyribonucleotidase, MAGNESIUM ION, [(5R)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-2,5-DIHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, ... (4 entities in total)
Functional Keywords	alfa beta fold, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion: Q9NPB1
Total number of polymer chains	1
Total formula weight	23192.94
Authors	Wallden, K.,Ruzzenente, B.,Rinaldo-Matthis, A.,Bianchi, V.,Nordlund, P. (deposition date: 2005-03-16, release date: 2005-07-26, Last modification date: 2021-11-10)
Primary citation	Wallden, K.,Ruzzenente, B.,Rinaldo-Matthis, A.,Bianchi, V.,Nordlund, P. Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase STRUCTURE, 13:1081-1088, 2005 Cited by PubMed: 16004879 DOI: 10.1016/j.str.2005.04.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation