1KY9
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![BU of 1ky9 by Molmil](/molmil-images/mine/1ky9) | Crystal Structure of DegP (HtrA) | Descriptor: | PROTEASE DO | Authors: | Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T. | Deposit date: | 2002-02-04 | Release date: | 2002-04-03 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine. Nature, 416, 2002
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3CS0
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![BU of 3cs0 by Molmil](/molmil-images/mine/3cs0) | Crystal structure of DegP24 | Descriptor: | Periplasmic serine endoprotease DegP, pentapeptide | Authors: | Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T. | Deposit date: | 2008-04-08 | Release date: | 2008-05-27 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the regulated protease and chaperone function of DegP Nature, 453, 2008
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6Z0E
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![BU of 6z0e by Molmil](/molmil-images/mine/6z0e) | |
6Z0X
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![BU of 6z0x by Molmil](/molmil-images/mine/6z0x) | |
6Z0Y
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![BU of 6z0y by Molmil](/molmil-images/mine/6z0y) | |
3NWU
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![BU of 3nwu by Molmil](/molmil-images/mine/3nwu) | Substrate induced remodeling of the active site regulates HtrA1 activity | Descriptor: | SULFATE ION, Serine protease HTRA1 | Authors: | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | Deposit date: | 2010-07-11 | Release date: | 2011-02-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat.Struct.Mol.Biol., 18, 2011
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3NUM
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![BU of 3num by Molmil](/molmil-images/mine/3num) | Substrate induced remodeling of the active site regulates HtrA1 activity | Descriptor: | Serine protease HTRA1 | Authors: | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | Deposit date: | 2010-07-07 | Release date: | 2011-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat.Struct.Mol.Biol., 18, 2011
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3NZI
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![BU of 3nzi by Molmil](/molmil-images/mine/3nzi) | Substrate induced remodeling of the active site regulates HtrA1 activity | Descriptor: | Citrate synthase, Serine protease HTRA1 | Authors: | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | Deposit date: | 2010-07-16 | Release date: | 2011-02-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat.Struct.Mol.Biol., 18, 2011
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4A8D
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![BU of 4a8d by Molmil](/molmil-images/mine/4a8d) | DegP dodecamer with bound OMP | Descriptor: | OUTER MEMBRANE PROTEIN C, PERIPLASMIC SERINE ENDOPROTEASE DEGP | Authors: | Malet, H, Krojer, T, Sawa, J, Schafer, E, Saibil, H.R, Ehrmann, M, Clausen, T. | Deposit date: | 2011-11-20 | Release date: | 2012-01-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (28 Å) | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
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1SOZ
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![BU of 1soz by Molmil](/molmil-images/mine/1soz) | Crystal Structure of DegS protease in complex with an activating peptide | Descriptor: | Protease degS, activating peptide | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | Deposit date: | 2004-03-16 | Release date: | 2004-06-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease Cell(Cambridge,Mass.), 117, 2004
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1SOT
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![BU of 1sot by Molmil](/molmil-images/mine/1sot) | Crystal Structure of the DegS stress sensor | Descriptor: | Protease degS | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | Deposit date: | 2004-03-15 | Release date: | 2004-06-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease Cell(Cambridge,Mass.), 117, 2004
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3STI
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![BU of 3sti by Molmil](/molmil-images/mine/3sti) | Crystal structure of the protease domain of DegQ from Escherichia coli | Descriptor: | Protease degQ | Authors: | Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T. | Deposit date: | 2011-07-11 | Release date: | 2011-07-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope. J.Biol.Chem., 286, 2011
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3STJ
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![BU of 3stj by Molmil](/molmil-images/mine/3stj) | Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli | Descriptor: | Protease degQ, peptide (UNK) | Authors: | Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T. | Deposit date: | 2011-07-11 | Release date: | 2011-07-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope. J.Biol.Chem., 286, 2011
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1VCW
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![BU of 1vcw by Molmil](/molmil-images/mine/1vcw) | Crystal structure of DegS after backsoaking the activating peptide | Descriptor: | Protease degS | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | Deposit date: | 2004-03-16 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease. Cell(Cambridge,Mass.), 117, 2004
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4A8A
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![BU of 4a8a by Molmil](/molmil-images/mine/4a8a) | Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme | Descriptor: | LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ | Authors: | Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. | Deposit date: | 2011-11-20 | Release date: | 2011-12-28 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (14.2 Å) | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
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4A9G
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![BU of 4a9g by Molmil](/molmil-images/mine/4a9g) | Symmetrized cryo-EM reconstruction of E. coli DegQ 24-mer in complex with beta-casein | Descriptor: | PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ | Authors: | Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. | Deposit date: | 2011-11-26 | Release date: | 2012-01-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
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4A8B
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![BU of 4a8b by Molmil](/molmil-images/mine/4a8b) | Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes | Descriptor: | LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ | Authors: | Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. | Deposit date: | 2011-11-20 | Release date: | 2012-01-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
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4A8C
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![BU of 4a8c by Molmil](/molmil-images/mine/4a8c) | Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with a binding peptide | Descriptor: | PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ | Authors: | Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. | Deposit date: | 2011-11-20 | Release date: | 2012-01-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
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2R3Y
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![BU of 2r3y by Molmil](/molmil-images/mine/2r3y) | |
6EW9
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![BU of 6ew9 by Molmil](/molmil-images/mine/6ew9) | CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNRLGLVYQF PEPTIDE, ... | Authors: | Vetter, I.R, Porfetye, A.T, Stege, P. | Deposit date: | 2017-11-03 | Release date: | 2018-04-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes. ACS Chem. Biol., 13, 2018
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2R3U
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![BU of 2r3u by Molmil](/molmil-images/mine/2r3u) | Crystal structure of the PDZ deletion mutant of DegS | Descriptor: | Protease degS | Authors: | Clausen, T, Kurzbauer, R. | Deposit date: | 2007-08-30 | Release date: | 2007-11-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress. Genes Dev., 21, 2007
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2ZLE
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![BU of 2zle by Molmil](/molmil-images/mine/2zle) | Cryo-EM structure of DegP12/OMP | Descriptor: | Outer membrane protein C, Protease do | Authors: | Schaefer, E, Saibil, H.R. | Deposit date: | 2008-04-09 | Release date: | 2008-06-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (28 Å) | Cite: | Structural basis for the regulated protease and chaperone function of DegP Nature, 453, 2008
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4RQZ
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![BU of 4rqz by Molmil](/molmil-images/mine/4rqz) | |
4RR0
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![BU of 4rr0 by Molmil](/molmil-images/mine/4rr0) | |
4RR1
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![BU of 4rr1 by Molmil](/molmil-images/mine/4rr1) | |