2WN9
 
 | | Crystal structure of Aplysia ACHBP in complex with 4-0H-DMXBA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(E)-5,6-DIHYDRO-2,3'-BIPYRIDIN-3(4H)-YLIDENEMETHYL]-3-METHOXYPHENOL, SOLUBLE ACETYLCHOLINE RECEPTOR, ... | | Authors: | Sulzenbacher, G, Hibbs, R, Shi, J, Talley, T, Conrod, S, Kem, W, Taylor, P, Marchot, P, Bourne, Y. | | Deposit date: | 2009-07-07 | | Release date: | 2009-09-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
Embo J., 28, 2009
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6MS7
 | | Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selective PPAR-gamma modulator VSP-77 | | Descriptor: | PGC1 LXXLL motif, Peroxisome proliferator-activated receptor gamma, {[(1S)-1-(4-chlorophenyl)octyl]oxy}acetic acid | | Authors: | Yi, W, Jiang, H, Zhou, X.E, Shi, J, Zhao, G, Zhang, X, Sun, Y, Suino-Powell, K, Li, J, Li, J, Melcher, K, Xu, H.E. | | Deposit date: | 2018-10-16 | | Release date: | 2019-10-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery.
Chem Sci, 11, 2020
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6LK0
 | | Crystal structure of human wild type TRIP13 | | Descriptor: | Pachytene checkpoint protein 2 homolog | | Authors: | Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J. | | Deposit date: | 2019-12-17 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
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6LNU
 | | Cryo-EM structure of immature Zika virus | | Descriptor: | Genome polyprotein | | Authors: | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | | Deposit date: | 2020-01-02 | | Release date: | 2020-02-26 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
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6LNT
 | | Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab | | Descriptor: | Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ... | | Authors: | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | | Deposit date: | 2020-01-02 | | Release date: | 2020-02-26 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
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5H37
 | | Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ... | | Authors: | Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M. | | Deposit date: | 2016-10-20 | | Release date: | 2016-11-30 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
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8KGF
 | | Structure of AmCas12a with crRNA | | Descriptor: | CRISPR-associated endonuclease Cas12a, MAGNESIUM ION, RNA (44-MER) | | Authors: | Feng, Y, Zhang, X, Shi, J, Ma, P, Tang, J, Huang, X. | | Deposit date: | 2023-08-18 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | A novel CRISPR/Cas12a in complex with a crRNA.
To Be Published
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6IDI
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 8.0. | | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | Deposit date: | 2018-09-10 | | Release date: | 2018-12-12 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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6IDK
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class I particle) | | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | Deposit date: | 2018-09-10 | | Release date: | 2018-12-12 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (25 Å) | | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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6IDL
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class II particle) | | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | Deposit date: | 2018-09-10 | | Release date: | 2018-12-12 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (25 Å) | | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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8Y6U
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8JN6
 | | Cryo-EM structure of the small tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | | Descriptor: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN3
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 37 deg C (subparticle LLR-LRR) | | Descriptor: | Envelope protein, Human antibody DENV-115 heavy chain, Human antibody DENV-115 light chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (5.4 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN7
 | | Cryo-EM structure of the big tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | | Descriptor: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (11 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN5
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 37 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN4
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 4 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN2
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 4 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-115 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN1
 | | Cryo-EM structure of dengue virus serotype 3 strain EHIE46200Y19 in complex with human antibody DENV-115 IgG at 4 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein (Fragment), Human antibody DENV-115 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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7CBP
 | | CryoEM structure of Zika virus with Fab at 4.1 Angstrom | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, Fab Heavy chain, ... | | Authors: | Tyagi, A, Ahmed, T, Shi, J, Bhushan, S. | | Deposit date: | 2020-06-13 | | Release date: | 2020-07-08 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 angstrom resolution.
J Struct Biol X, 4, 2020
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7DWT
 | | Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 1 particle) | | Descriptor: | Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein | | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | Deposit date: | 2021-01-18 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (19 Å) | | Cite: | Antibody affinity versus dengue morphology influences neutralization.
Plos Pathog., 17, 2021
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7DWU
 | | Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 2 particle) | | Descriptor: | Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein | | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | Deposit date: | 2021-01-18 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (19 Å) | | Cite: | Antibody affinity versus dengue morphology influences neutralization.
Plos Pathog., 17, 2021
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1JZW
 | | Arsenate Reductase + Sodium Arsenate From E. coli | | Descriptor: | ARSENATE REDUCTASE, CESIUM ION, SULFATE ION, ... | | Authors: | Martin, P, DeMel, S, Shi, J, Gladysheva, T, Gatti, D.L, Rosen, B.P, Edwards, B.F. | | Deposit date: | 2001-09-17 | | Release date: | 2001-11-28 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme.
Structure, 9, 2001
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2QDY
 | | Crystal Structure of Fe-type NHase from Rhodococcus erythropolis AJ270 | | Descriptor: | 2-METHYLPROPAN-1-AMINE, CHLORIDE ION, FE (III) ION, ... | | Authors: | Song, L, Shi, J, Xue, Z, Wang, M.-X, Qian, S. | | Deposit date: | 2007-06-22 | | Release date: | 2008-05-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | High resolution X-ray molecular structure of the nitrile hydratase from Rhodococcus erythropolis AJ270 reveals posttranslational oxidation of two cysteines into sulfinic acids and a novel biocatalytic nitrile hydration mechanism
Biochem.Biophys.Res.Commun., 362, 2007
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5WSO
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5X8P
 | | Structure of the 70S chloroplast ribosome from spinach | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | Authors: | Ahmed, T, Shi, J, Bhushan, S. | | Deposit date: | 2017-03-03 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation
Nucleic Acids Res., 45, 2017
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