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Crystal structure of a glutamine amidotransferase (tm1158) from thermotoga maritima at 1.70 A resolution
Descriptor:	SULFATE ION, conserved hypothetical protein TM1158
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-02-12
Release date:	2003-03-11
Last modified:	2023-01-25
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution. PROTEINS, 54, 2004

1O50

Crystal structure of a cbs domain-containing protein (tm0935) from thermotoga maritima at 1.87 A resolution
Descriptor:	CBS domain-containing predicted protein TM0935
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-07-31
Release date:	2003-08-12
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (1.87 Å)
Cite:	Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution Proteins, 57, 2004

1O5H

Crystal structure of formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution
Descriptor:	Formiminotetrahydrofolate cyclodeaminase
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-09-17
Release date:	2003-09-30
Last modified:	2023-01-25
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold Proteins, 58, 2005

1O20

Crystal structure of Gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.00 A resolution
Descriptor:	Gamma-glutamyl phosphate reductase
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-02-12
Release date:	2003-04-01
Last modified:	2023-01-25
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution. Proteins, 54, 2004

1O4S

Crystal structure of Aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution
Descriptor:	Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-06-26
Release date:	2003-07-08
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution Proteins, 55, 2004

1O4V

Crystal structure of the catalytic subunit of a phosphoribosylaminoimidazole mutase (tm0446) from thermotoga maritima at 1.77 A resolution
Descriptor:	SULFATE ION, phosphoribosylaminoimidazole mutase PurE
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-07-11
Release date:	2003-07-22
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.77 Å)
Cite:	Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77 A resolution Proteins, 55, 2004

1O51

Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.50 A resolution
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Hypothetical protein TM0021, SULFATE ION
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-08-01
Release date:	2003-08-19
Last modified:	2023-01-25
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution Proteins, 54, 2004

1O59

Crystal structure of Allantoicase (yir029w) from Saccharomyces cerevisiae at 2.40 A resolution
Descriptor:	Allantoicase
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-08-22
Release date:	2003-09-02
Last modified:	2023-01-25
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution Proteins, 56, 2004

1O4T

Crystal structure of a predicted oxalate decarboxylase (tm1287) from thermotoga maritima at 1.95 A resolution
Descriptor:	MANGANESE (II) ION, OXALATE ION, putative oxalate decarboxylase
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-07-03
Release date:	2003-07-15
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution Proteins, 56, 2004

1O3U

Crystal structure of an hepn domain protein (tm0613) from thermotoga maritima at 1.75 A resolution
Descriptor:	conserved hypothetical protein TM0613
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-03-28
Release date:	2003-04-22
Last modified:	2023-01-25
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution. PROTEINS, 54, 2004

1O22

Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00 A resolution
Descriptor:	orphan protein TM0875
Authors:	Joint Center for Structural Genomics (JCSG)
Deposit date:	2003-02-15
Release date:	2003-04-01
Last modified:	2023-01-25
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold. Proteins, 56, 2004

2HWN

Crystal Structure of RII alpha Dimerization/Docking domain of PKA bound to the D-AKAP2 peptide
Descriptor:	A Kinase binding peptide, GLYCEROL, cAMP-dependent protein kinase type II-alpha regulatory subunit
Authors:	Kinderman, F, Kim, C.
Deposit date:	2006-08-01
Release date:	2006-11-21
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase. Mol.Cell, 24, 2006

2IJM

Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Focal Adhesion Kinase 1
Authors:	Lee, C.C.
Deposit date:	2006-09-29
Release date:	2007-08-14
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.187 Å)
Cite:	Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds To be Published

6VHG

Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrazolo[1,5-a]pyrimidine inhibitor
Descriptor:	3-(3,4-dimethoxyphenyl)-N~5~-(1-methylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine, ACETATE ION, CHLORIDE ION, ...
Authors:	Lee, C.C, Spraggon, G.
Deposit date:	2020-01-09
Release date:	2020-02-26
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.303 Å)
Cite:	Efficacy and Tolerability of Pyrazolo[1,5-a]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma. Acs Med.Chem.Lett., 11, 2020

1B98

NEUROTROPHIN 4 (HOMODIMER)
Descriptor:	CHLORIDE ION, PROTEIN (NEUROTROPHIN-4)
Authors:	Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S.
Deposit date:	1999-02-22
Release date:	1999-02-26
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci., 8, 1999

4Z55

Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
Descriptor:	ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Authors:	Lee, C.C, Spraggon, G.
Deposit date:	2015-04-02
Release date:	2016-02-03
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.55 Å)
Cite:	Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors. Bioorg.Med.Chem.Lett., 26, 2016

2Y7S

Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
Descriptor:	FACTOR H BINDING PROTEIN
Authors:	Malito, E, Spraggon, G, Bottomley, M.J.
Deposit date:	2011-02-01
Release date:	2011-07-27
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity. Sci.Transl.Med, 3, 2011

1S17

Identification of Novel Potent Bicyclic Peptide Deformylase Inhibitors
Descriptor:	2-(3,4-DIHYDRO-3-OXO-2H-BENZO[B][1,4]THIAZIN-2-YL)-N-HYDROXYACETAMIDE, GLYCEROL, NICKEL (II) ION, ...
Authors:	Molteni, V, He, X, Nabakka, J, Yang, K, Kreusch, A, Gordon, P, Bursulaya, B, Ryder, N.S, Goldberg, R, He, Y.
Deposit date:	2004-01-05
Release date:	2004-03-30
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Identification of novel potent bicyclic peptide deformylase inhibitors Bioorg.Med.Chem.Lett., 14, 2004

1HCF

Crystal structure of TrkB-d5 bound to neurotrophin-4/5
Descriptor:	BDNF/NT-3 GROWTH FACTORS RECEPTOR, NEUROTROPHIN-4, SULFATE ION
Authors:	Banfield, M.J, Naylor, R.L, Robertson, A.G.S, Allen, S.J, Dawbarn, D, Brady, R.L.
Deposit date:	2001-05-03
Release date:	2001-12-06
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Specificity in Trk-Receptor:Neurotrophin Interaction: The Crystal Structure of Trkb-D5 in Complex with Neurotrophin-4/5 Structure, 9, 2001

1N8E

Fragment Double-D from Human Fibrin
Descriptor:	Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain
Authors:	Yang, Z, Pandi, L, Doolittle, R.F.
Deposit date:	2002-11-20
Release date:	2003-01-07
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (4.5 Å)
Cite:	The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface Biochemistry, 41, 2002

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