Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8Y2C
DownloadVisualize
BU of 8y2c by Molmil
Cryo-EM structure of human dopamine transporter in apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium-dependent dopamine transporter
Authors:Zhao, Y, Li, Y.
Deposit date:2024-01-25
Release date:2024-08-14
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2E
DownloadVisualize
BU of 8y2e by Molmil
Cryo-EM structure of human dopamine transporter in complex with benztropine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium-dependent dopamine transporter, benztropine
Authors:Zhao, Y, Li, Y.
Deposit date:2024-01-25
Release date:2024-08-14
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2G
DownloadVisualize
BU of 8y2g by Molmil
Cryo-EM structure of human dopamine transporter in complex with methylphenidate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Dexmethylphenidate, ...
Authors:Zhao, Y, Li, Y.
Deposit date:2024-01-25
Release date:2024-08-14
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2F
DownloadVisualize
BU of 8y2f by Molmil
Cryo-EM structure of human dopamine transporter in complex with GBR12909
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium-dependent dopamine transporter, Vanoxerine
Authors:Zhao, Y, Li, Y.
Deposit date:2024-01-25
Release date:2024-08-14
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2D
DownloadVisualize
BU of 8y2d by Molmil
Cryo-EM structure of human dopamine transporter in complex with dopamine
Descriptor: CHLORIDE ION, L-DOPAMINE, SODIUM ION, ...
Authors:Zhao, Y, Li, Y.
Deposit date:2024-01-25
Release date:2024-08-14
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
7Y5N
DownloadVisualize
BU of 7y5n by Molmil
Structure of 1:1 PAPP-A.ProMBP complex(half map)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone marrow proteoglycan, ...
Authors:Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
Deposit date:2022-06-17
Release date:2023-01-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
7Y5Q
DownloadVisualize
BU of 7y5q by Molmil
Structure of 1:1 PAPP-A.STC2 complex(half map)
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION
Authors:Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
Deposit date:2022-06-17
Release date:2023-01-11
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
5C7M
DownloadVisualize
BU of 5c7m by Molmil
CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5C7J
DownloadVisualize
BU of 5c7j by Molmil
CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
7E3L
DownloadVisualize
BU of 7e3l by Molmil
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 58G6 heavy chain, 58G6 light chain, ...
Authors:Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H.
Deposit date:2021-02-09
Release date:2021-09-15
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants.
Nat Commun, 12, 2021
7E3K
DownloadVisualize
BU of 7e3k by Molmil
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
Descriptor: 13G9 heavy chain, 13G9 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H.
Deposit date:2021-02-09
Release date:2021-09-15
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants.
Nat Commun, 12, 2021
6XIF
DownloadVisualize
BU of 6xif by Molmil
PCSK9(deltaCRD) in complex with cyclic peptide 83
Descriptor: GLYCEROL, Peptide 83, Proprotein convertase subtilisin/kexin type 9
Authors:Orth, P.
Deposit date:2020-06-19
Release date:2020-11-18
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.774 Å)
Cite:Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design.
J.Med.Chem., 63, 2020
8IVQ
DownloadVisualize
BU of 8ivq by Molmil
Cryo-EM structure of mouse BIRC6, Global map
Descriptor: Isoform 2 of Baculoviral IAP repeat-containing protein 6
Authors:Liu, S, Jiang, T, Bu, F, Zhao, J, Wang, G, Li, N, Gao, N, Qiu, X.
Deposit date:2023-03-28
Release date:2024-01-24
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy.
Nat Commun, 15, 2024
7S5H
DownloadVisualize
BU of 7s5h by Molmil
PCSK9(deltaCRD) in complex with cyclic peptide 35
Descriptor: (2E)-but-2-ene-1,4-diol, Pro-peptide from Proprotein convertase subtilisin/kexin type 9, Proprotein convertase subtilisin/kexin type 9, ...
Authors:Orth, P.
Deposit date:2021-09-10
Release date:2021-11-03
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.272 Å)
Cite:A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors.
J.Med.Chem., 64, 2021
7S5G
DownloadVisualize
BU of 7s5g by Molmil
PCSK9 in complex with compound 19
Descriptor: (2E)-but-2-ene-1,4-diol, GLYCEROL, Propeptide of Proprotein convertase subtilisin/kexin type 9, ...
Authors:Orth, P.
Deposit date:2021-09-10
Release date:2021-11-03
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.041 Å)
Cite:A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors.
J.Med.Chem., 64, 2021
4WSJ
DownloadVisualize
BU of 4wsj by Molmil
Crystal structure of a bacterial fucodiase in complex with 1-((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)ethan-1-one
Descriptor: Alpha-L-fucosidase, N-[(1S,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methylcyclohexyl]acetamide, SULFATE ION
Authors:Davies, G.J, Wright, D.W.
Deposit date:2014-10-28
Release date:2014-11-05
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:In vitroandin vivocomparative and competitive activity-based protein profiling of GH29 alpha-l-fucosidases.
Chem Sci, 6, 2015
4WSK
DownloadVisualize
BU of 4wsk by Molmil
Crystal structure of a bacterial fucosidase with phenyl((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)methanone
Descriptor: Alpha-L-fucosidase, IMIDAZOLE, N-[(1S,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methylcyclohexyl]benzamide, ...
Authors:Davies, G.J.
Deposit date:2014-10-28
Release date:2014-11-12
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:In vitroandin vivocomparative and competitive activity-based protein profiling of GH29 alpha-l-fucosidases.
Chem Sci, 6, 2015
5DP9
DownloadVisualize
BU of 5dp9 by Molmil
Crystal Structure of EV71 3C Proteinase in complex with compound 9
Descriptor: 3C proteinase, ethyl (2Z,4S)-4-[(N-{[(cyclobutylmethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP8
DownloadVisualize
BU of 5dp8 by Molmil
Crystal Structure of EV71 3C Proteinase in complex with compound 8
Descriptor: 3C proteinase, ethyl (2Z,4S)-4-[(N-{[(2-cyclopropylethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DPA
DownloadVisualize
BU of 5dpa by Molmil
Crystal Structure of EV71 3C Proteinase in complex with compound 6
Descriptor: 3C proteinase, ethyl (2Z,4S)-4-[(N-acetyl-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP3
DownloadVisualize
BU of 5dp3 by Molmil
Crystal Structure of EV71 3C Proteinase in complex with compound 2
Descriptor: 3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate
Authors:Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP4
DownloadVisualize
BU of 5dp4 by Molmil
Crystal Structure of EV71 3C Proteinase in complex with compound 3
Descriptor: 3C proteinase, ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP5
DownloadVisualize
BU of 5dp5 by Molmil
Crystal Structure of EV71 3C Proteinase in complex with compound 4
Descriptor: 3C proteinase, ethyl (2Z,4S)-4-{[(2R,5S)-5-amino-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP7
DownloadVisualize
BU of 5dp7 by Molmil
Crystal Structure of EV71 3C Proteinase in complex with compound 5
Descriptor: 3C proteinase, ethyl (2Z,4S)-4-{[N-(3-methylbutanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
6KXS
DownloadVisualize
BU of 6kxs by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Li, Y, Wang, G, Xiao, J.
Deposit date:2019-09-12
Release date:2020-02-05
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into immunoglobulin M.
Science, 367, 2020

227561

건을2024-11-20부터공개중

PDB statisticsPDBj update infoContact PDBjnumon