6IEC
 
 | | Structure of RVFV Gn and human monoclonal antibody R17 | | Descriptor: | NSmGnGc, R17 H chain, R17 L chain | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
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6IEA
 | | Structure of RVFV Gn and human monoclonal antibody R13 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NSmGnGc, ... | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
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6IEK
 | | Structure of RVFV Gn and human monoclonal antibody R12 | | Descriptor: | Heavy chain of Fab R12, Light chain of Fab R12, NSmGnGc | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-14 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
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8IKH
 | | Cryo-EM structure of human receptor with G proteins | | Descriptor: | 3-[(1R)-1-(2-methoxyphenyl)-2-nitro-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Shen, S.Y, Shao, Z.H. | | Deposit date: | 2023-02-28 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure-based identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8IKG
 | | Cryo-EM structure of human receptor with G proteins | | Descriptor: | 3-[(1S)-1-(furan-2-yl)-2-nitro-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Shen, S.Y, Shao, Z.H. | | Deposit date: | 2023-02-28 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure-based identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8JIL
 | | Cryo-EM structure of niacin bound ketone body receptor HCAR2-Gi signaling complex | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | Deposit date: | 2023-05-26 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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8JII
 | | Cryo-EM structure of compound 9n and niacin bound ketone body receptor HCAR2-Gi signaling complex | | Descriptor: | 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | Deposit date: | 2023-05-26 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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8JHY
 | | Cryo-EM structure of compound 9n bound ketone body receptor HCAR2-Gi signaling complex | | Descriptor: | 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | Deposit date: | 2023-05-25 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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8JIM
 | | Cryo-EM structure of MMF bound ketone body receptor HCAR2-Gi signaling complex | | Descriptor: | (2Z)-4-methoxy-4-oxobut-2-enoic acid, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | Deposit date: | 2023-05-26 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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6ITP
 | | Crystal structure of cortisol complexed with its nanobody at pH 3.5 | | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, anti-cortisol camelid antibody | | Authors: | Ding, Y, Ding, L.L, Wang, Z.Y, Zhong, P.Y. | | Deposit date: | 2018-11-24 | | Release date: | 2019-07-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.572 Å) | | Cite: | Structural insights into the mechanism of single domain VHH antibody binding to cortisol.
Febs Lett., 593, 2019
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6ITQ
 | | Crystal structure of cortisol complexed with its nanobody at pH 10.5 | | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, SULFATE ION, anti-cortisol camelid antibody | | Authors: | Ding, Y, Ding, L.L, Wang, Z.Y, Zhong, P.Y. | | Deposit date: | 2018-11-24 | | Release date: | 2019-07-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.526 Å) | | Cite: | Structural insights into the mechanism of single domain VHH antibody binding to cortisol.
Febs Lett., 593, 2019
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8H9I
 | | Human ATP synthase F1 domain, state2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9Q
 | | Human ATP synthase state 3b subregion 3 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9R
 | | Human ATP synthase state 3b subregion 2 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.97 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9P
 | | Human ATP synthase F1 domain, state 3b | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9U
 | | Human ATP synthase state 3a (combined) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9V
 | | Human ATP synthase state 3b (combined) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9N
 | | Human ATP synthase state 3a subregion 2 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9M
 | | Human ATP synthase state 3a subregion 3 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9E
 | | Human ATP synthase F1 domain, state 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.53 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9S
 | | Human ATP synthase state 1 (combined) | | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.53 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9K
 | | Human ATP synthase state 2 subregion 2 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9G
 | | Human ATP synthase state 1 subregion 2 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9L
 | | Human ATP synthase F1 domain, state 3a | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9J
 | | Human ATP synthase state2 subregion 3 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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