6J1L
| Crystal Structure Analysis of the ROR gamma(C455E) | Descriptor: | 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide, Nuclear receptor ROR-gamma | Authors: | zhang, Y, Li, C.C, wu, X.S. | Deposit date: | 2018-12-28 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. J.Med.Chem., 62, 2019
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3LZC
| Crystal structure of Dph2 from Pyrococcus horikoshii | Descriptor: | Dph2 | Authors: | Zhang, Y, Zhu, X, Torelli, A.T, Lee, M, Dzikovski, B, Koralewski, R.M, Wang, E, Freed, J, Krebs, C, Lin, H, Ealick, S.E. | Deposit date: | 2010-03-01 | Release date: | 2010-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.261 Å) | Cite: | Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme. Nature, 465, 2010
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4OIN
| Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 | Descriptor: | (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... | Authors: | Zhang, Y, Ebright, R.H, Arnold, E. | Deposit date: | 2014-01-20 | Release date: | 2014-05-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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4OIR
| Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked with GE23077 and rifamycin SV | Descriptor: | (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... | Authors: | Zhang, Y, Ebright, R.H, Arnold, E. | Deposit date: | 2014-01-20 | Release date: | 2014-05-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.105 Å) | Cite: | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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3T94
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2L80
| Solution Structure of the Zinc Finger Domain of USP13 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 13, ZINC ION | Authors: | Zhang, Y, Zhou, C, Zhou, Z, Song, A, Hu, H. | Deposit date: | 2010-12-28 | Release date: | 2011-12-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Biochemical Characterization of the Ubiquitin Receptors in USP13 Reveals Different Catalytic Activation of Deubiquitination from Its Analogue USP5 To be Published
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2LLQ
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2LRJ
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2MES
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2M1Z
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8INE
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8IPD
| human nuclear pre-60S ribosomal particle - State C | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-14 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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8IDT
| human nuclear pre-60S ribosomal particle - State G | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-02-14 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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8IPY
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8INF
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8IR1
| human nuclear pre-60S ribosomal particle - State A | Descriptor: | 28S rRNA, 5.8S rRMA, 5S RNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-17 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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8IR3
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8IE3
| human nuclear pre-60S ribosomal particle - State E | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-02-15 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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8IPX
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8IDY
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8INK
| human nuclear pre-60S ribosomal particle - State D | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-10 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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2OF6
| Structure of immature West Nile virus | Descriptor: | envelope glycoprotein E | Authors: | Zhang, Y, Kaufmann, B, Chipman, P.R, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2007-01-02 | Release date: | 2007-04-03 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (24 Å) | Cite: | Structure of immature west nile virus. J.Virol., 81, 2007
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2PQN
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2PQR
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2NOX
| Crystal structure of tryptophan 2,3-dioxygenase from Ralstonia metallidurans | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase | Authors: | Zhang, Y, Kang, S.A, Mukherjee, T, Bale, S, Crane, B.R, Begley, T.P, Ealick, S.E. | Deposit date: | 2006-10-26 | Release date: | 2006-12-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis. Biochemistry, 46, 2007
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