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7RE8
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BU of 7re8 by Molmil
Class I MHC (HLA-A*02) presenting alpha fetoprotein peptide (AFP)
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, MHC class I antigen, ...
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
7RE7
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BU of 7re7 by Molmil
TCR mimic antibody (Fab fragment) in complex with AFP/HLA-A*02
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, FORMIC ACID, ...
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
1P9G
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BU of 1p9g by Molmil
Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Ecommia ulmoides Oliver at atomic resolution
Descriptor: ACETATE ION, EAFP 2
Authors:Xiang, Y, Huang, R.H, Liu, X.Z, Wang, D.C.
Deposit date:2003-05-12
Release date:2004-06-01
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (0.84 Å)
Cite:Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Eucommia ulmoides Oliver at an atomic resolution.
J.Struct.Biol., 148, 2004
2OQO
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BU of 2oqo by Molmil
Crystal structure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis
Descriptor: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Penicillin-binding protein 1A (PBP-1a) (PBP1a)
Authors:Yuan, Y, Sliz, P, Walker, S.
Deposit date:2007-01-31
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis.
Proc.Natl.Acad.Sci.Usa, 104, 2007
6XF5
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BU of 6xf5 by Molmil
Cryo-EM structure of a biotinylated SARS-CoV-2 spike probe in the prefusion state (RBDs down)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2020-06-15
Release date:2020-09-02
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
SSRN, 2020
5LG4
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BU of 5lg4 by Molmil
Crystal structure of the Sec3/Sso2 complex at 2.9 angstrom resolution
Descriptor: Exocyst complex component SEC3, Protein SSO2, SULFATE ION
Authors:Zhang, Y.B, Dong, G.
Deposit date:2016-07-05
Release date:2017-02-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
4KXF
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BU of 4kxf by Molmil
Crystal structure of NLRC4 reveals its autoinhibition mechanism
Descriptor: ADENOSINE-5'-DIPHOSPHATE, NLR family CARD domain-containing protein 4, SULFATE ION
Authors:Chai, J, Hu, Z.
Deposit date:2013-05-25
Release date:2013-07-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of NLRC4 reveals its autoinhibition mechanism
Science, 341, 2013
4NSW
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BU of 4nsw by Molmil
Crystal structure of the BAR-PH domain of ACAP1
Descriptor: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Authors:Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F.
Deposit date:2013-11-29
Release date:2014-10-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A PH Domain in ACAP1 Possesses Key Features of the BAR Domain in Promoting Membrane Curvature
Dev.Cell, 31, 2014
6XF6
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BU of 6xf6 by Molmil
Cryo-EM structure of a biotinylated SARS-CoV-2 spike probe in the prefusion state (1 RBD up)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2020-06-15
Release date:2020-09-02
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
SSRN, 2020
5M4Y
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BU of 5m4y by Molmil
Crystal structure of the Sec3/Sso2 complex at 2.20 angstrom resolution
Descriptor: Exocyst complex component SEC3, GLYCEROL, Protein SSO2
Authors:Zhang, Y.B, Dong, G.
Deposit date:2016-10-19
Release date:2017-02-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
6IVE
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BU of 6ive by Molmil
Molecular structure of a thermostable and a Zinc ion binding gamma-class carbonic anhydrase
Descriptor: Ferripyochelin-binding protein, PHOSPHATE ION, ZINC ION
Authors:Wang, W.M, Wang, H.F.
Deposit date:2018-12-03
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular structure of thermostable and zinc-ion-binding gamma-class carbonic anhydrases.
Biometals, 32, 2019
1YO6
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BU of 1yo6 by Molmil
Crystal Structure of the putative Carbonyl Reductase Sniffer of Caenorhabditis elegans
Descriptor: Putative Carbonyl Reductase Sniffer
Authors:Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-01-26
Release date:2005-02-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the putative Carbonyl Reductase Sniffer of Caenorhabditis elegans
To be Published
6IYW
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BU of 6iyw by Molmil
Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with Imipenem adduct
Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, GLYCEROL, L,D-transpeptidase 2
Authors:Li, D.F, Zhao, F, Wang, D.C.
Deposit date:2018-12-17
Release date:2019-02-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem.
Biochem. Biophys. Res. Commun., 510, 2019
6IYY
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BU of 6iyy by Molmil
Crystal structure of human WIPI3,loop deletion mutant
Descriptor: SULFATE ION, WD repeat domain phosphoinositide-interacting protein 3
Authors:Liang, R.B, Ren, J.Q, Feng, W.
Deposit date:2018-12-17
Release date:2019-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Structural Conservation of the Two Phosphoinositide-Binding Sites in WIPI Proteins.
J. Mol. Biol., 431, 2019
4K6H
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BU of 4k6h by Molmil
Crystal structure of CALB mutant L278M from Candida antarctica
Descriptor: 1,2-ETHANEDIOL, Lipase B
Authors:An, J, Xie, Y, Feng, Y, Wu, G.
Deposit date:2013-04-15
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Enhanced enzyme kinetic stability by increasing rigidity within the active site.
J.Biol.Chem., 289, 2014
4K5Q
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BU of 4k5q by Molmil
Crystal structure of CALB mutant DGLM from Candida antarctica
Descriptor: Lipase B
Authors:An, J, Xie, Y, Feng, Y, Wu, G.
Deposit date:2013-04-15
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Enhanced enzyme kinetic stability by increasing rigidity within the active site.
J.Biol.Chem., 289, 2014
4K6K
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BU of 4k6k by Molmil
Crystal structure of CALB mutant D223G from Candida antarctica
Descriptor: 1,2-ETHANEDIOL, Lipase B
Authors:An, J, Xie, Y, Feng, Y, Wu, G.
Deposit date:2013-04-16
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Enhanced enzyme kinetic stability by increasing rigidity within the active site.
J.Biol.Chem., 289, 2014
1YQ1
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BU of 1yq1 by Molmil
Structural Genomics Of Caenorhabditis Elegans: glutathione S-Transferase
Descriptor: glutathione S-Transferase
Authors:Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-01-31
Release date:2005-02-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Genomics of Caenorhabditis Elegans: glutathione S-Transferase
To be Published
4K6G
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BU of 4k6g by Molmil
Crystal structure of CALB from Candida antarctica
Descriptor: 1,2-ETHANEDIOL, Lipase B
Authors:An, J, Xie, Y, Feng, Y, Wu, G.
Deposit date:2013-04-15
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enhanced enzyme kinetic stability by increasing rigidity within the active site.
J.Biol.Chem., 289, 2014
2PJT
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BU of 2pjt by Molmil
Crystal structure of the catalytic domain of MMP-13 complexed with WAY-344
Descriptor: CALCIUM ION, Collagenase 3, TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE, ...
Authors:Xu, Z, Huang, A, Lovering, F, Levin, J.I, Mosyak, L.
Deposit date:2007-04-16
Release date:2008-04-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based design of TACE selective inhibitors: manipulations in the S1'-S3' pocket.
Bioorg.Med.Chem., 15, 2007
8XGC
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BU of 8xgc by Molmil
Structure of yeast replisome associated with FACT and histone hexamer, Composite map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
Authors:Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y.
Deposit date:2023-12-15
Release date:2024-02-14
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Parental histone transfer caught at the replication fork.
Nature, 627, 2024
5YFG
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BU of 5yfg by Molmil
SOLUTION STRUCTURE OF HUMAN MOG1
Descriptor: Ran guanine nucleotide release factor
Authors:Hu, Q, Liu, Y, Bao, X, Liu, H.
Deposit date:2017-09-21
Release date:2017-11-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation
J Mol Cell Biol, 10, 2018
4GA7
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BU of 4ga7 by Molmil
Crystal structure of human serpinB1 mutant
Descriptor: Leukocyte elastase inhibitor
Authors:Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
4GAW
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BU of 4gaw by Molmil
Crystal structure of active human granzyme H
Descriptor: CHLORIDE ION, Granzyme H, SULFATE ION
Authors:Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
6A0Z
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BU of 6a0z by Molmil
Crystal structure of broadly neutralizing antibody 13D4 bound to H5N1 influenza hemagglutinin, HA head region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 13D4, Fab Heavy Chain, ...
Authors:Li, S, Li, T.
Deposit date:2018-06-06
Release date:2018-06-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.329 Å)
Cite:Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus.
J. Virol., 92, 2018

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