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4I3N
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BU of 4i3n by Molmil
Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease mutant D61N
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2012-11-26
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
4I37
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BU of 4i37 by Molmil
Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease mutant R402G
Descriptor: Ryanodine receptor 1
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2012-11-25
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
4I6I
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BU of 4i6i by Molmil
Crystal structure of rabbit ryanodine receptor 1 (residues 1-559) disease mutant R45C
Descriptor: Ryanodine receptor 1
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2012-11-29
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
4KEJ
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BU of 4kej by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R169Q
Descriptor: Ryanodine receptor 2
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2013-04-25
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.553 Å)
Cite:Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4I2S
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BU of 4i2s by Molmil
Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease mutant I404M
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2012-11-22
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
4KEI
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BU of 4kei by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S
Descriptor: Ryanodine receptor 2
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2013-04-25
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEK
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BU of 4kek by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R176Q
Descriptor: Ryanodine receptor 2, SULFATE ION
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2013-04-25
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.146 Å)
Cite:Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4I7I
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BU of 4i7i by Molmil
Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease mutant L14R
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2012-11-30
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
4I96
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BU of 4i96 by Molmil
Crystal structure of the N-terminal two domains of the skeletal muscle ryanodine receptor (rabbit RyR1) residues 217-536
Descriptor: Ryanodine receptor 1
Authors:Kimlicka, L, Tung, C.C, Van Petegem, F.
Deposit date:2012-12-04
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
4L4I
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BU of 4l4i by Molmil
Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547 disease mutant R420Q
Descriptor: GLYCEROL, Ryanodine receptor 2
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2013-06-07
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of ryanodine receptor disease mutant
To be Published
4L4H
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BU of 4l4h by Molmil
Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Ryanodine receptor 2, ...
Authors:Kimlicka, L, Tung, C.C, Van Petegem, F.
Deposit date:2013-06-07
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a ryanodine receptor domain
To be Published
4ETU
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BU of 4etu by Molmil
Crystal structure of rabbit ryanodine receptor 1 mutant R2939S
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4DJC
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BU of 4djc by Molmil
1.35 A crystal structure of the NaV1.5 DIII-IV-Ca/CaM complex
Descriptor: CALCIUM ION, Calmodulin, ISOPROPYL ALCOHOL, ...
Authors:Sarhan, M.F, Tung, C.-C, Van Petegem, F, Ahern, C.A.
Deposit date:2012-02-01
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystallographic basis for calcium regulation of sodium channels.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ERT
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BU of 4ert by Molmil
Crystal structure of rabbit ryanodine receptor 1 (2734-2940)
Descriptor: GLYCEROL, POTASSIUM ION, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-20
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ESU
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BU of 4esu by Molmil
Crystal structure of rabbit ryanodine receptor 1 mutant S2776M
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-23
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ERV
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BU of 4erv by Molmil
Crystal structure of human ryanodine receptor 3 (2597-2800)
Descriptor: GLYCEROL, Ryanodine receptor 3, SULFATE ION
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-20
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ETV
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BU of 4etv by Molmil
Crystal structure of mouse ryanodine receptor 2 (2699-2904)
Descriptor: CHLORIDE ION, Ryanodine receptor 2
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ETT
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BU of 4ett by Molmil
Crystal structure of rabbit ryanodine receptor 1 mutant E2764K
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
8DUJ
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BU of 8duj by Molmil
Global map in C1 of RyR1 particles in complex with ImperaCalcin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
Authors:Haji-Ghassemi, O, Van Petegm, F.
Deposit date:2022-07-27
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DRP
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BU of 8drp by Molmil
Focus/local refined map in C4 of signal subtracted RyR1 particles
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Ryanodine receptor 1, ...
Authors:Haji-Ghassemi, O, Van Petegm, F.
Deposit date:2022-07-21
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DTB
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BU of 8dtb by Molmil
Focus/local refined map in C1 of signal subtracted RyR1 particles in complex with ImperaCalcin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Imperacalcin, ...
Authors:Haji-Ghassemi, O, Van Petegm, F.
Deposit date:2022-07-25
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DVE
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BU of 8dve by Molmil
RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
Authors:Haji-Ghassemi, O, Van Petegm, F.
Deposit date:2022-07-28
Release date:2023-05-31
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
6Y94
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BU of 6y94 by Molmil
Ca2+-bound Calmodulin mutant N53I
Descriptor: CALCIUM ION, Calmodulin
Authors:Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
Deposit date:2020-03-06
Release date:2020-04-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6Y95
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BU of 6y95 by Molmil
Ca2+-free Calmodulin mutant N53I
Descriptor: Calmodulin
Authors:Holt, C, Hamborg, L.N, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
Deposit date:2020-03-06
Release date:2020-04-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6C5I
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BU of 6c5i by Molmil
Unliganded S25-5 Fab
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Evans, S.V, Haji-Ghassemi, O.
Deposit date:2018-01-16
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019

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