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8IC6
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BU of 8ic6 by Molmil
exo-beta-D-arabinanase ExoMA2 from Microbacterium arabinogalactanolyticum in complex with Tris
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Fukushima, R, Kashima, T, Ishiwata, A, Fujita, K, Fushinobu, S.
Deposit date:2023-02-10
Release date:2023-08-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.
Nat Commun, 14, 2023
8IC8
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BU of 8ic8 by Molmil
Exo-alpha-D-arabinofuranosidase from Microbacterium arabinogalactanolyticum
Descriptor: Exo-alpha-D-arabinofuranosidase, PHOSPHATE ION
Authors:Kashima, T, Arakawa, T, Yamada, C, Ishiwata, A, Fujita, K, Fushinobu, S.
Deposit date:2023-02-11
Release date:2023-08-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.
Nat Commun, 14, 2023
8HHV
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BU of 8hhv by Molmil
endo-alpha-D-arabinanase EndoMA1 from Microbacterium arabinogalactanolyticum
Descriptor: CALCIUM ION, GLYCEROL, SODIUM ION, ...
Authors:Nakashima, C, Li, J, Arakawa, T, Yamada, C, Ishiwata, A, Fujita, K, Fushinobu, S.
Deposit date:2022-11-17
Release date:2023-08-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.
Nat Commun, 14, 2023
1IDZ
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BU of 1idz by Molmil
STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, 20 STRUCTURES
Descriptor: MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
Authors:Furukawa, K, Oda, M, Nakamura, H.
Deposit date:1996-08-15
Release date:1996-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.
Proc.Natl.Acad.Sci.USA, 93, 1996
1IDY
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BU of 1idy by Molmil
STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
Authors:Furukawa, K, Oda, M, Nakamura, H.
Deposit date:1996-08-15
Release date:1996-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.
Proc.Natl.Acad.Sci.USA, 93, 1996
2RDV
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BU of 2rdv by Molmil
RUBREDOXIN FROM DESULFOVIBRIO VULGARIS MIYAZAKI F, MONOCLINIC CRYSTAL FORM
Descriptor: FE (III) ION, RUBREDOXIN
Authors:Higuchi, Y, Yasuoka, N.
Deposit date:1998-10-07
Release date:1999-05-18
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure determination of rubredoxin from Desulfovibrio vulgaris Miyazaki F in two crystal forms.
Acta Crystallogr.,Sect.D, 55, 1999
2ZMF
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BU of 2zmf by Molmil
Crystal structure of the C-terminal GAF domain of human phosphodiesterase 10A
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Authors:Handa, N, Kishishita, S, Mizohata, E, Omori, K, Kotera, J, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-04-17
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP
J.Biol.Chem., 283, 2008
6OHD
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BU of 6ohd by Molmil
P38 in complex with T-3220137
Descriptor: 3-(3-tert-butyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-4-methyl-N-(1,2-oxazol-3-yl)benzamide, Mitogen-activated protein kinase 14
Authors:Lane, W, Saikatendu, K.
Deposit date:2019-04-05
Release date:2019-11-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]Pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 2.
Chemmedchem, 14, 2019
6M9L
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BU of 6m9l by Molmil
Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping - compound 10
Descriptor: 3-benzyl-6-[(2,4-difluorophenyl)amino]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, Mitogen-activated protein kinase 14
Authors:Lane, W, Okada, K.
Deposit date:2018-08-23
Release date:2019-04-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1.
Chemmedchem, 14, 2019
6M95
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BU of 6m95 by Molmil
Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping: compound 1
Descriptor: (4-benzylpiperidin-1-yl)[2-methoxy-4-(methylsulfanyl)phenyl]methanone, Mitogen-activated protein kinase 14
Authors:Lane, W, Okada, K.
Deposit date:2018-08-22
Release date:2019-04-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1.
Chemmedchem, 14, 2019
1C4E
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BU of 1c4e by Molmil
GURMARIN FROM GYMNEMA SYLVESTRE
Descriptor: PROTEIN (GURMARIN)
Authors:Fletcher, J.I, Dingley, A.J, King, G.F.
Deposit date:1999-07-27
Release date:1999-08-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:High-resolution solution structure of gurmarin, a sweet-taste-suppressing plant polypeptide.
Eur.J.Biochem., 264, 1999
2RVM
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BU of 2rvm by Molmil
Solution structure of the chromodomain of HP1alpha with the phosphorylated N-terminal tail
Descriptor: Chromobox protein homolog 5
Authors:Kawaguchi, A, Nishimura, Y.
Deposit date:2015-12-18
Release date:2016-03-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2RVN
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BU of 2rvn by Molmil
Solution structure of the chromodomain of HP1a with the phosphorylated N-terminal tail complexed with H3K9me3 peptide
Descriptor: 18-mer peptide of Histone H3, Chromobox protein homolog 5
Authors:Kawaguchi, A, Nishimura, Y.
Deposit date:2015-12-18
Release date:2016-03-16
Method:SOLUTION NMR
Cite:Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2RVL
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BU of 2rvl by Molmil
Solution structure of the chromodomain of HP1alpha with the N-terminal tail
Descriptor: Chromobox protein homolog 5
Authors:Kawaguchi, A, Nishimura, Y.
Deposit date:2015-12-18
Release date:2016-03-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
8CI8
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BU of 8ci8 by Molmil
Cryo-EM structure of the Nup98(298-327) fibril
Descriptor: Nuclear pore complex protein Nup98
Authors:Ibanez de Opakua, A, Cima-Omori, S, Dienemann, C, Zweckstetter, M.
Deposit date:2023-02-09
Release date:2024-02-21
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Impact of distinct FG nucleoporin repeats on Nup98 self-association.
Nat Commun, 15, 2024
1RDV
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BU of 1rdv by Molmil
RUBREDOXIN FROM DESULFOVIBRIO VULGARIS MIYAZAKI F, TRIGONAL CRYSTAL FORM
Descriptor: FE (III) ION, RUBREDOXIN
Authors:Higuchi, Y, Yasuoka, N.
Deposit date:1998-09-30
Release date:1999-05-18
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure determination of rubredoxin from Desulfovibrio vulgaris Miyazaki F in two crystal forms.
Acta Crystallogr.,Sect.D, 55, 1999
7XW8
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BU of 7xw8 by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct
Descriptor: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ...
Authors:Oki, H.
Deposit date:2022-05-26
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects.
Eur.J.Med.Chem., 239, 2022
8OTG
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BU of 8otg by Molmil
CTE typeI tau filament from Kii ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTH
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BU of 8oth by Molmil
TypeII tau filament from Kii ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTD
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BU of 8otd by Molmil
TMEM106B Fold1-s filament from Guam ALS/PDC
Descriptor: Transmembrane protein 106B
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTC
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BU of 8otc by Molmil
CTE typeII tau filament from Guam ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTF
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BU of 8otf by Molmil
Ab typeII filament from Guam ALS/PDC
Descriptor: Amyloid-beta precursor protein
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTE
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BU of 8ote by Molmil
TMEM106B Fold I-d filament from Guam ALS/PDC
Descriptor: Transmembrane protein 106B
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT6
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BU of 8ot6 by Molmil
CTE typeI tau filament from Guam ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTJ
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BU of 8otj by Molmil
PHF tau filament from Kii ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023

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