5EYK
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![BU of 5eyk by Molmil](/molmil-images/mine/5eyk) | CRYSTAL STRUCTURE OF AURORA B IN COMPLEX WITH BI 847325 | Descriptor: | 3-[(3~{Z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{H}-indol-6-yl]-~{N}-ethyl-prop-2-ynamide, Aurora kinase B-A, Inner centromere protein A | Authors: | Bader, G, Zoephel, A. | Deposit date: | 2015-11-25 | Release date: | 2016-08-17 | Last modified: | 2016-10-19 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases. Mol.Cancer Ther., 15, 2016
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6U9U
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![BU of 6u9u by Molmil](/molmil-images/mine/6u9u) | Structure of GM9_TH8seq732127 FAB | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ... | Authors: | Singh, S, Liban, T.J, Pancera, M. | Deposit date: | 2019-09-09 | Release date: | 2019-11-06 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J.Exp.Med., 217, 2020
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6U3Z
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![BU of 6u3z by Molmil](/molmil-images/mine/6u3z) | Structure of VD20_5A4 Fab | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Dionne, G, Shapiro, L. | Deposit date: | 2019-08-22 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.99002314 Å) | Cite: | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J.Exp.Med., 217, 2020
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7EKB
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![BU of 7ekb by Molmil](/molmil-images/mine/7ekb) | Crystal structure of 4E10 modified with pyrene acetamide | Descriptor: | ACETATE ION, Fab region of the heavy chain of broadly neutralizing antibody anti-HIV-1 4E10, Fab region of the light chain of the broadly neutralizing anti-HIV-1 antibody 4E10, ... | Authors: | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | Deposit date: | 2021-04-05 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile. Iscience, 24, 2021
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7EKK
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![BU of 7ekk by Molmil](/molmil-images/mine/7ekk) | Anti-HIV-1 broadly neutralizing antibody delta-loop 4E10 modified with pyrene acetamide | Descriptor: | AMMONIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | Deposit date: | 2021-04-05 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile. Iscience, 24, 2021
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5JDT
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![BU of 5jdt by Molmil](/molmil-images/mine/5jdt) | Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K | Descriptor: | AZIDE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | Deposit date: | 2016-04-17 | Release date: | 2016-09-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling. J.Am.Chem.Soc., 138, 2016
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4IUM
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![BU of 4ium by Molmil](/molmil-images/mine/4ium) | Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin | Descriptor: | GLYCEROL, Ubiquitin, ZINC ION, ... | Authors: | Bailey-Elkin, B.A, James, T.W, Mark, B.L. | Deposit date: | 2013-01-21 | Release date: | 2013-02-13 | Last modified: | 2013-03-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells. Proc.Natl.Acad.Sci.USA, 110, 2013
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3LSA
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![BU of 3lsa by Molmil](/molmil-images/mine/3lsa) | Padron0.9-OFF (non-fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
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3C4J
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![BU of 3c4j by Molmil](/molmil-images/mine/3c4j) | ABC protein ArtP in complex with ATP-gamma-S | Descriptor: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. | Deposit date: | 2008-01-30 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region To be Published
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3LS3
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![BU of 3ls3 by Molmil](/molmil-images/mine/3ls3) | Padron0.9-ON (fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
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3CUH
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![BU of 3cuh by Molmil](/molmil-images/mine/3cuh) | |
3CUJ
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6EK8
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![BU of 6ek8 by Molmil](/molmil-images/mine/6ek8) | YaxB from Yersinia enterocolitica | Descriptor: | YaxB | Authors: | Braeuning, B, Groll, M. | Deposit date: | 2017-09-25 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB. Nat Commun, 9, 2018
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3CUI
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6EK4
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![BU of 6ek4 by Molmil](/molmil-images/mine/6ek4) | PaxB from Photorhabdus luminescens | Descriptor: | PaxB, SODIUM ION | Authors: | Braeuning, B, Groll, M. | Deposit date: | 2017-09-25 | Release date: | 2018-05-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB. Nat Commun, 9, 2018
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6EL1
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![BU of 6el1 by Molmil](/molmil-images/mine/6el1) | YaxAB pore complex | Descriptor: | YaxA, YaxB | Authors: | Braeuning, B, Bertosin, E, Dietz, H, Groll, M. | Deposit date: | 2017-09-27 | Release date: | 2018-05-16 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB. Nat Commun, 9, 2018
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6EK7
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![BU of 6ek7 by Molmil](/molmil-images/mine/6ek7) | YaxA from Yersinia enterocolitica | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, YaxA | Authors: | Braeuning, B, Groll, M. | Deposit date: | 2017-09-25 | Release date: | 2018-05-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB. Nat Commun, 9, 2018
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3C41
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![BU of 3c41 by Molmil](/molmil-images/mine/3c41) | ABC protein ArtP in complex with AMP-PNP/Mg2+ | Descriptor: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. | Deposit date: | 2008-01-29 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region To be Published
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3CUF
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3CUG
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![BU of 3cug by Molmil](/molmil-images/mine/3cug) | |
4BKR
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![BU of 4bkr by Molmil](/molmil-images/mine/4bkr) | Enoyl-ACP reductase from Yersinia pestis (wildtype, removed Histag) with cofactor NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Hirschbeck, M.W, Neckles, C, Tonge, P.J, Kisker, C. | Deposit date: | 2013-04-29 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase. Biochemistry, 55, 2016
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4BKQ
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![BU of 4bkq by Molmil](/molmil-images/mine/4bkq) | Enoyl-ACP reductase from Yersinia pestis (wildtype)with cofactor NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PUTATIVE REDUCTASE YPZ3_3519 | Authors: | Hirschbeck, M.W, Neckles, C, Tonge, P.J, Kisker, C. | Deposit date: | 2013-04-29 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase. Biochemistry, 55, 2016
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6TEO
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![BU of 6teo by Molmil](/molmil-images/mine/6teo) | Crystal structure of a yeast Snu114-Prp8 complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | Authors: | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | Deposit date: | 2019-11-12 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Res., 48, 2020
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3GVA
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3GX4
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![BU of 3gx4 by Molmil](/molmil-images/mine/3gx4) | Crystal Structure Analysis of S. Pombe ATL in complex with DNA | Descriptor: | Alkyltransferase-like protein 1, COBALT HEXAMMINE(III), DNA (5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3'), ... | Authors: | Tubbs, J.L, Arvai, A.S, Tainer, J.A. | Deposit date: | 2009-04-01 | Release date: | 2009-06-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature, 459, 2009
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