4BKR

Enoyl-ACP reductase from Yersinia pestis (wildtype, removed Histag) with cofactor NADH

Summary for 4BKR

• Entry DOI: 10.2210/pdb4bkr/pdb
• Related: 4BKO 4BKQ 4BKU
• Descriptor: PUTATIVE REDUCTASE YPZ3_3519, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, ... (6 entities in total)
• Functional Keywords: oxidoreductase, fatty acid biosynthesis, enoyl-acp reductase
• Biological source: YERSINIA PESTIS
• Total number of polymer chains: 1
• Total formula weight: 45154.59

Authors

Hirschbeck, M.W.,Neckles, C.,Tonge, P.J.,Kisker, C. (deposition date: 2013-04-29, release date: 2014-05-14, Last modification date: 2023-12-20)

• Primary citation: Neckles, C.,Pschibul, A.,Lai, C.,Hirschbeck, M.,Kuper, J.,Davoodi, S.,Zou, J.,Liu, N.,Pan, P.,Shah, S.,Daryaee, F.,Bommineni, G.R.,Lai, C.,Simmerling, C.,Kisker, C.,Tonge, P.J.; Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.; Biochemistry, 55:2992-, 2016; PubMed: 27136302; DOI: 10.1021/ACS.BIOCHEM.5B01301

Experimental method

X-RAY DIFFRACTION (1.798 Å)