2DIK
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![BU of 2dik by Molmil](/molmil-images/mine/2dik) | R337A MUTANT OF PYRUVATE PHOSPHATE DIKINASE | Descriptor: | PROTEIN (PYRUVATE PHOSPHATE DIKINASE), SULFATE ION | Authors: | Huang, K, Herzberg, O. | Deposit date: | 1998-09-03 | Release date: | 1999-09-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Location of the phosphate binding site within Clostridium symbiosum pyruvate phosphate dikinase. Biochemistry, 37, 1998
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2FM4
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1DIK
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![BU of 1dik by Molmil](/molmil-images/mine/1dik) | PYRUVATE PHOSPHATE DIKINASE | Descriptor: | PYRUVATE PHOSPHATE DIKINASE, SULFATE ION | Authors: | Herzberg, O, Chen, C.C.H. | Deposit date: | 1995-12-06 | Release date: | 1996-04-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Swiveling-domain mechanism for enzymatic phosphotransfer between remote reaction sites. Proc.Natl.Acad.Sci.USA, 93, 1996
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4GAH
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![BU of 4gah by Molmil](/molmil-images/mine/4gah) | Human acyl-CoA thioesterases 4 in complex with undecan-2-one-CoA inhibitor | Descriptor: | Thioesterase superfamily member 4, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3R)-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-[(2R)-2-oxidanylundecyl]sulfanylethylamino]propyl]amino]butyl] hydrogen phosphate | Authors: | Lim, K, Pathak, M.C, Herzberg, O. | Deposit date: | 2012-07-25 | Release date: | 2012-08-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Correlation of structure and function in the human hotdog-fold enzyme hTHEM4. Biochemistry, 51, 2012
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3FM9
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![BU of 3fm9 by Molmil](/molmil-images/mine/3fm9) | Analysis of the Structural Determinants Underlying Discrimination between Substrate and Solvent in beta-Phosphoglucomutase Catalysis | Descriptor: | Beta-phosphoglucomutase, MAGNESIUM ION | Authors: | Finci, L, Lahiri, S, Peisach, E, Allen, K.N. | Deposit date: | 2008-12-19 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis. Biochemistry, 48, 2009
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6UPC
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6UPB
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6UPE
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6UPD
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![BU of 6upd by Molmil](/molmil-images/mine/6upd) | Structure of trehalose-6-phosphate phosphatase from Salmonella typhimurium in complex with trehalose | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Trehalose-phosphate phosphatase, ... | Authors: | Harvey, C.M, O'Toole, K.H, Allen, K.N. | Deposit date: | 2019-10-17 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Structural Analysis of Binding Determinants ofSalmonella typhimuriumTrehalose-6-phosphate Phosphatase Using Ground-State Complexes. Biochemistry, 59, 2020
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3B8I
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3L8E
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![BU of 3l8e by Molmil](/molmil-images/mine/3l8e) | Crystal Structure of apo form of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli | Descriptor: | ACETIC ACID, D,D-heptose 1,7-bisphosphate phosphatase, ZINC ION | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | Deposit date: | 2009-12-31 | Release date: | 2010-02-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) . Biochemistry, 49, 2010
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2F0X
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![BU of 2f0x by Molmil](/molmil-images/mine/2f0x) | Crystal structure and function of human thioesterase superfamily member 2(THEM2) | Descriptor: | SULFATE ION, Thioesterase superfamily member 2 | Authors: | Cheng, Z, Song, F, Shan, X, Wang, Y, Wei, Z, Gong, W. | Deposit date: | 2005-11-14 | Release date: | 2006-10-10 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of human thioesterase superfamily member 2 Biochem.Biophys.Res.Commun., 349, 2006
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3L8G
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![BU of 3l8g by Molmil](/molmil-images/mine/3l8g) | Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with D-glycero-D-manno-heptose 1 ,7-bisphosphate | Descriptor: | 1,7-di-O-phosphono-L-glycero-beta-D-manno-heptopyranose, D,D-heptose 1,7-bisphosphate phosphatase, MAGNESIUM ION, ... | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | Deposit date: | 2009-12-31 | Release date: | 2010-02-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) . Biochemistry, 49, 2010
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3L8H
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![BU of 3l8h by Molmil](/molmil-images/mine/3l8h) | Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from B. bronchiseptica complexed with magnesium and phosphate | Descriptor: | FORMIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | Deposit date: | 2009-12-31 | Release date: | 2010-02-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) . Biochemistry, 49, 2010
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2DUA
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3MN1
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![BU of 3mn1 by Molmil](/molmil-images/mine/3mn1) | Crystal structure of probable yrbi family phosphatase from pseudomonas syringae pv.phaseolica 1448a | Descriptor: | CHLORIDE ION, probable yrbi family phosphatase | Authors: | Patskovsky, Y, Ramagopal, U, Toro, R, Freeman, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-04-20 | Release date: | 2010-04-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the divergence of substrate specificity and biological function within HAD phosphatases in lipopolysaccharide and sialic acid biosynthesis. Biochemistry, 52, 2013
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3OHI
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![BU of 3ohi by Molmil](/molmil-images/mine/3ohi) | Structure of Giardia fructose-1,6-biphosphate aldolase in complex with 3-hydroxy-2-pyridone | Descriptor: | ({3-hydroxy-2-oxo-4-[2-(phosphonooxy)ethyl]pyridin-1(2H)-yl}methyl)phosphonic acid, Putative fructose-1,6-bisphosphate aldolase, ZINC ION | Authors: | Herzberg, O, Galkin, A. | Deposit date: | 2010-08-17 | Release date: | 2011-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Rational design, synthesis and evaluation of first generation inhibitors of the Giardia lamblia fructose-1,6-biphosphate aldolase. J.Inorg.Biochem., 105, 2010
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5E0O
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3N07
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![BU of 3n07 by Molmil](/molmil-images/mine/3n07) | Structure of putative 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase from Vibrio cholerae | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, MAGNESIUM ION | Authors: | Liu, W, Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-13 | Release date: | 2010-08-04 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural basis for the divergence of substrate specificity and biological function within HAD phosphatases in lipopolysaccharide and sialic acid biosynthesis. Biochemistry, 52, 2013
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3F5O
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![BU of 3f5o by Molmil](/molmil-images/mine/3f5o) | Crystal Structure of hTHEM2(undecan-2-one-CoA) complex | Descriptor: | CHLORIDE ION, COENZYME A, HEXAETHYLENE GLYCOL, ... | Authors: | Xu, H, Gong, W. | Deposit date: | 2008-11-04 | Release date: | 2009-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis Biochemistry, 48, 2009
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3KZF
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![BU of 3kzf by Molmil](/molmil-images/mine/3kzf) | Structure of Giardia Carbamate Kinase | Descriptor: | Carbamate kinase, GLYCEROL | Authors: | Galkin, A, Herzberg, O. | Deposit date: | 2009-12-08 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray structure and characterization of carbamate kinase from the human parasite Giardia lamblia. Acta Crystallogr.,Sect.F, 66, 2010
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3L8F
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![BU of 3l8f by Molmil](/molmil-images/mine/3l8f) | Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with magnesium and phosphate | Descriptor: | D,D-heptose 1,7-bisphosphate phosphatase, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | Deposit date: | 2009-12-31 | Release date: | 2010-02-02 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) . Biochemistry, 49, 2010
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2ISV
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![BU of 2isv by Molmil](/molmil-images/mine/2isv) | Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, Putative fructose-1,6-bisphosphate aldolase, ZINC ION | Authors: | Galkin, A, Herzberg, O. | Deposit date: | 2006-10-18 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia. J.Biol.Chem., 282, 2007
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2ISW
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![BU of 2isw by Molmil](/molmil-images/mine/2isw) | Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, Putative fructose-1,6-bisphosphate aldolase, ZINC ION | Authors: | Galkin, A, Herzberg, O. | Deposit date: | 2006-10-18 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia. J.Biol.Chem., 282, 2007
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2HJP
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