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7AXQ
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BU of 7axq by Molmil
Structure of the cryo-trapped WDR5:CS-VIP8 cocrystal after illumination at 405 nm and 180 K
Descriptor: CS-VIP8, WD repeat-containing protein 5
Authors:Werel, L, Essen, L.-O.
Deposit date:2020-11-10
Release date:2021-12-15
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.562 Å)
Cite:Bistable Photoswitch Allows in Vivo Control of Hematopoiesis.
Acs Cent.Sci., 8, 2022
7AXX
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BU of 7axx by Molmil
Structure of WDR5:CS-VIP8 crystal after illumination at 405 nm and room temperature
Descriptor: (ALQ)(4FO)R(ABA)(DPN)(EDN)(S7Z), WD repeat-containing protein 5
Authors:Werel, L, Essen, L.-O.
Deposit date:2020-11-10
Release date:2021-12-15
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Bistable Photoswitch Allows in Vivo Control of Hematopoiesis.
Acs Cent.Sci., 8, 2022
7AXP
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BU of 7axp by Molmil
Structural characterisation of WDR5:CS-VIP8 interaction in cis state 2
Descriptor: CS-VIP8, WD repeat-containing protein 5
Authors:Werel, L, Essen, L.-O.
Deposit date:2020-11-10
Release date:2021-12-15
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.432 Å)
Cite:Bistable Photoswitch Allows in Vivo Control of Hematopoiesis.
Acs Cent.Sci., 8, 2022
7AXS
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BU of 7axs by Molmil
Structural characterisation of WDR5:CS-VIP8 interaction in cis state 1
Descriptor: CS-VIP8, (ALQ)(4FO)R(ABA)(DPN)(EDN)(S7Z), WD repeat-containing protein 5
Authors:Werel, L, Essen, L.-O.
Deposit date:2020-11-10
Release date:2021-12-15
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Bistable Photoswitch Allows in Vivo Control of Hematopoiesis.
Acs Cent.Sci., 8, 2022
2O8G
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BU of 2o8g by Molmil
Rat pp1c gamma complexed with mouse inhibitor-2
Descriptor: MANGANESE (II) ION, Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Authors:Hurley, T.D.
Deposit date:2006-12-12
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
J.Biol.Chem., 282, 2007
2O8A
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BU of 2o8a by Molmil
rat PP1cgamma complexed with mouse inhibitor-2
Descriptor: Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Authors:Hurley, T.D.
Deposit date:2006-12-12
Release date:2007-07-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
J.Biol.Chem., 282, 2007
4YSJ
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BU of 4ysj by Molmil
Calcium-Dependent Protein Kinase from Eimeria tenella in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin-like domain protein kinase, ...
Authors:Merritt, E.A.
Deposit date:2015-03-17
Release date:2016-04-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:CDPK is a druggable target in the apicomplexan parasite Eimeria
to be published
7V33
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BU of 7v33 by Molmil
Active state complex I from rotenone-NADH dataset
Descriptor: (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
Authors:Gu, J.K, Yang, M.J.
Deposit date:2021-08-10
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7V3M
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BU of 7v3m by Molmil
Deactive state complex I from rotenone-NADH dataset
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Gu, J.K, Yang, M.J.
Deposit date:2021-08-10
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
6BSE
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BU of 6bse by Molmil
Glucocorticoid receptor bound to high cooperativity monomer sequence
Descriptor: DNA (5'-D(P*AP*CP*CP*AP*CP*GP*TP*GP*TP*AP*CP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*AP*GP*TP*AP*CP*AP*CP*GP*TP*GP*G)-3'), Glucocorticoid receptor, ...
Authors:Pufall, M.A.
Deposit date:2017-12-02
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry
To Be Published
7WHD
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BU of 7whd by Molmil
SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (2u1d)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Zeng, J.W, Wang, X.W, Ge, J.W, Wang, Z.Y.
Deposit date:2021-12-30
Release date:2023-01-18
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters 1 .
Emerg Microbes Infect, 12, 2023
7XSS
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BU of 7xss by Molmil
Structure of Craspase-CTR
Descriptor: CHAT domain protein, RAMP superfamily protein, RNA (34-MER), ...
Authors:Feng, Y, Zang, L.X.
Deposit date:2022-05-15
Release date:2022-11-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Target RNA activates the protease activity of Craspase to confer antiviral defense.
Mol.Cell, 82, 2022
7XST
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BU of 7xst by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike glycoprotein in complex with three F61 Fab and three D2 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ...
Authors:Wang, X, Li, X.
Deposit date:2022-05-15
Release date:2022-11-23
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
2MJY
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BU of 2mjy by Molmil
Solution structure of synthetic Mamba-1 peptide
Descriptor: Mambalgin-1
Authors:He, Y, Wu, F, Tian, C.
Deposit date:2014-01-21
Release date:2015-01-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:One-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1
Chem.Commun.(Camb.), 50, 2014
8HL1
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BU of 8hl1 by Molmil
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ...
Authors:Wang, Y.H, Zhou, J.
Deposit date:2022-11-28
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Nucleic Acids Res., 51, 2023
3I7B
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BU of 3i7b by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor NM-PP1
Descriptor: 1,2-ETHANEDIOL, 1-(1-methylethyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, ...
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-07-08
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.988 Å)
Cite:Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors.
Nat.Struct.Mol.Biol., 17, 2010
3ID6
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BU of 3id6 by Molmil
Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex
Descriptor: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, Pre mRNA splicing protein, S-ADENOSYLMETHIONINE
Authors:Ye, K.
Deposit date:2009-07-20
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural organization of box C/D RNA-guided RNA methyltransferase.
Proc.Natl.Acad.Sci.USA, 106, 2009
3I7C
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BU of 3i7c by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor NA-PP2
Descriptor: 1-tert-butyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-07-08
Release date:2010-02-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors.
Nat.Struct.Mol.Biol., 17, 2010
8I8Y
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BU of 8i8y by Molmil
A mutant of the C-terminal complex of proteins 4.1G and NuMA
Descriptor: Engineered protein
Authors:Hu, X.
Deposit date:2023-02-06
Release date:2023-04-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Combined prediction and design reveals the target recognition mechanism of an intrinsically disordered protein interaction domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8T9Z
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BU of 8t9z by Molmil
Structural of M8C10 Fab in complex human metapneumovirus fusion protein
Descriptor: Fusion glycoprotein F0, M8C10 Fab Heavy Chain, M8C10 Fab Light Chain
Authors:Su, H.P, Eddins, M.J, Shipman, J.M, Kostas, J, Reid, J.C.
Deposit date:2023-06-26
Release date:2023-11-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.995 Å)
Cite:Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface.
J.Virol., 97, 2023
3I7F
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BU of 3i7f by Molmil
Aspartyl tRNA synthetase from Entamoeba histolytica
Descriptor: Aspartyl-tRNA synthetase
Authors:Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-07-08
Release date:2009-07-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica.
Mol.Biochem.Parasitol., 169, 2010
3EZX
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BU of 3ezx by Molmil
Structure of Methanosarcina barkeri monomethylamine corrinoid protein
Descriptor: 5-HYDROXYBENZIMIDAZOLYLCOBAMIDE, MAGNESIUM ION, Monomethylamine corrinoid protein 1
Authors:Jain, R.
Deposit date:2008-10-23
Release date:2009-12-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structure of Methanosarcina barkeri monomethylamine corrinoid protein
TO BE PUBLISHED
3I79
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BU of 3i79 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1)
Descriptor: 1,2-ETHANEDIOL, Calmodulin-domain protein kinase 1
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-07-08
Release date:2009-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors.
Nat.Struct.Mol.Biol., 17, 2010
3ICX
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BU of 3icx by Molmil
Crystal structure of Sulfolobus solfataricus Nop5 (135-380)
Descriptor: Pre mRNA splicing protein, SULFATE ION
Authors:Ye, K.
Deposit date:2009-07-19
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural organization of box C/D RNA-guided RNA methyltransferase.
Proc.Natl.Acad.Sci.USA, 106, 2009
3ID5
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BU of 3id5 by Molmil
Crystal structure of Sulfolobus solfataricus C/D RNP assembled with Nop5, fibrillarin, L7Ae and a split half C/D RNA
Descriptor: 50S ribosomal protein L7Ae, Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, Pre mRNA splicing protein, ...
Authors:Ye, K.
Deposit date:2009-07-20
Release date:2009-08-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (4.01 Å)
Cite:Structural organization of box C/D RNA-guided RNA methyltransferase.
Proc.Natl.Acad.Sci.USA, 106, 2009

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