4JEZ
 
 | | N79R mutant of N-acetylornithine aminotransferase complexed with L-canaline | | Descriptor: | (2S)-2-azanyl-4-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]oxy-butanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | | Authors: | Bisht, S, Bharath, S.R, Murthy, M.R.N. | | Deposit date: | 2013-02-27 | | Release date: | 2014-03-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases
To be Published
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4JEV
 | | N-acetylornithine aminotransferase from S. typhimurium complexed with gabaculine | | Descriptor: | 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ... | | Authors: | Bisht, S, Bharath, S.R, Murthy, M.R.N. | | Deposit date: | 2013-02-27 | | Release date: | 2014-03-26 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases.
To be Published
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4JF1
 | | R144Q mutant of N-acetylornithine aminotransferase | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ... | | Authors: | Bisht, S, Bharath, S.R, Murthy, M.R.N. | | Deposit date: | 2013-02-27 | | Release date: | 2014-03-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases
To be Published
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4GAD
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4JF0
 | | N79R mutant of N-acetylornithine aminotransferase | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ... | | Authors: | Bisht, S, Bharath, S.R, Murthy, M.R.N. | | Deposit date: | 2013-02-27 | | Release date: | 2014-03-26 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases
To be Published
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4JEW
 | | N-acetylornithine aminotransferase from S. typhimurium complexed with L-canaline | | Descriptor: | (2S)-2-azanyl-4-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]oxy-butanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | | Authors: | Bisht, S, Bharath, S.R, Murthy, M.R.N. | | Deposit date: | 2013-02-27 | | Release date: | 2014-03-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases.
To be Published
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4JEY
 | | E198A mutant of N-acetylornithine aminotransferase from Salmonella typhimurium | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ... | | Authors: | Bisht, S, Bharath, S.R, Murthy, M.R.N. | | Deposit date: | 2013-02-27 | | Release date: | 2014-03-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases
To be Published
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4X22
 | | Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM) | | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Triosephosphate isomerase | | Authors: | Pareek, V, Balaram, P, Murthy, M.R.N. | | Deposit date: | 2014-11-25 | | Release date: | 2016-02-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.084 Å) | | Cite: | Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme
Chembiochem, 17, 2016
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4YMZ
 | | DHAP bound Leptospira Interrogans Triosephosphate Isomerase (LiTIM) | | Descriptor: | 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, SULFATE ION, ... | | Authors: | Pareek, V, Balaram, P, Murthy, M.R.N. | | Deposit date: | 2015-03-08 | | Release date: | 2016-03-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme
Chembiochem, 17, 2016
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1O5Q
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2H6R
 | | Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii | | Descriptor: | Triosephosphate isomerase | | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | Deposit date: | 2006-06-01 | | Release date: | 2007-02-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii
Acta Crystallogr.,Sect.D, 63, 2007
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2E7R
 | | Crystal structure of Glu54 to Arg mutant of Diphthine synthase | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-01-12 | | Release date: | 2007-07-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
To be Published
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2EGB
 | | Crystal structure of Glu140 to Asn mutant of Diphthine synthase | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-28 | | Release date: | 2007-08-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
To be Published
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2EGL
 | | Crystal structure of Glu171 to Lys mutant of Diphthine synthase | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-01 | | Release date: | 2007-09-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
To be Published
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2EGS
 | | Crystal structure of Leu261 to Met mutant of Diphthine synthase | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-02 | | Release date: | 2007-09-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
To be Published
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1WOB
 | | Structure of a loop6 hinge mutant of Plasmodium falciparum Triosephosphate Isomerase, W168F, complexed to sulfate | | Descriptor: | SULFATE ION, Triosephosphate isomerase | | Authors: | Eaazhisai, K, Balaram, H, Balaram, P, Murthy, M.R.N. | | Deposit date: | 2004-08-12 | | Release date: | 2004-10-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structures of Unliganded and Inhibitor Complexes of W168F, a Loop6 Hinge Mutant of Plasmodium falciparum Triosephosphate Isomerase: Observation of an Intermediate Position of Loop6
J.Mol.Biol., 343, 2004
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1WOA
 | | Structure of the loop6 hinge mutant of Plasmodium falciparum Triosephosphate Isomerase, W168F, complexed with Glycerol-2-phosphate | | Descriptor: | 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL DIHYDROGEN PHOSPHATE, Triosephosphate isomerase | | Authors: | Eaazhisai, K, Balaram, H, Balaram, P, Murthy, M.R.N. | | Deposit date: | 2004-08-12 | | Release date: | 2004-10-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structures of Unliganded and Inhibitor Complexes of W168F, a Loop6 Hinge Mutant of Plasmodium falciparum Triosephosphate Isomerase: Observation of an Intermediate Position of Loop6
J.Mol.Biol., 343, 2004
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1ZYO
 | | Crystal Structure of the Serine Protease Domain of Sesbania Mosaic Virus polyprotein | | Descriptor: | GLYCEROL, serine protease | | Authors: | Gayathri, P, Satheshkumar, P.S, Prasad, K, Savithri, H.S, Murthy, M.R.N. | | Deposit date: | 2005-06-10 | | Release date: | 2006-04-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the serine protease domain of Sesbania mosaic virus polyprotein and mutational analysis of residues forming the S1-binding pocket
Virology, 346, 2006
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3SK3
 | | Crystal structure of Salmonella typhimurium acetate kinase (AckA) with citrate bound at the dimeric interface | | Descriptor: | 1,2-ETHANEDIOL, Acetate kinase, CITRIC ACID | | Authors: | Chittori, S, Savithri, H.S, Murthy, M.R.N. | | Deposit date: | 2011-06-22 | | Release date: | 2012-08-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface
Bmc Struct.Biol., 12, 2012
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3R0X
 | | Crystal structure of Selenomethionine incorporated apo D-serine deaminase from Salmonella tyhimurium | | Descriptor: | 1,2-ETHANEDIOL, D-serine dehydratase, SODIUM ION, ... | | Authors: | Bharath, S.R, Shveta, B, Savithri, H.S, Murthy, M.R.N. | | Deposit date: | 2011-03-09 | | Release date: | 2011-06-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Crystal structures of open and closed forms of D-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis
Febs J., 2011
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3SLC
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3R0Z
 | | Crystal structure of apo D-serine deaminase from Salmonella typhimurium | | Descriptor: | 1,2-ETHANEDIOL, D-serine dehydratase, SULFATE ION | | Authors: | Bharath, S.R, Shveta, B, Savithri, H.S, Murthy, M.R.N. | | Deposit date: | 2011-03-09 | | Release date: | 2011-06-29 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of open and closed forms of D-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis
Febs J., 2011
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3PSW
 | | Structure of E97Q mutant of TIM from Plasmodium falciparum | | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Triosephosphate isomerase | | Authors: | Samanta, M, Murthy, M.R.N, Balaram, H, Balaram, P. | | Deposit date: | 2010-12-02 | | Release date: | 2011-10-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Revisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residue
Chembiochem, 12, 2011
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2VFG
 | | Crystal structure of the F96H mutant of Plasmodium falciparum triosephosphate isomerase with 3-phosphoglycerate bound at the dimer interface | | Descriptor: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | Deposit date: | 2007-11-04 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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2VMT
 | | Crystal structure of Y60AbsSHMT L-Ser external aldimine | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Rajaram, V, Pai, V.R, Bisht, S, Bhavani, B.S, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | | Deposit date: | 2008-01-29 | | Release date: | 2008-12-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Structural and Functional Studies of Bacillus Stearothermophilus Serine Hydroxymethyltransferase: The Role of Asn(341), Tyr(60) and Phe(351) in Tetrahydrofolate Binding.
Biochem.J., 418, 2009
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