4X22

Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM)

Summary for 4X22

Entry DOI	10.2210/pdb4x22/pdb
Descriptor	Triosephosphate isomerase, 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ... (4 entities in total)
Functional Keywords	tim barrels, beta-alpha barrels, isomerase
Biological source	Leptospira interrogans serovar Icterohaemorrhagiae str. RGA
Total number of polymer chains	1
Total formula weight	27637.72
Authors	Pareek, V.,Balaram, P.,Murthy, M.R.N. (deposition date: 2014-11-25, release date: 2016-02-10, Last modification date: 2024-03-20)
Primary citation	Pareek, V.,Samanta, M.,Joshi, N.V.,Balaram, H.,Murthy, M.R.N.,Balaram, P. Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme Chembiochem, 17:620-629, 2016 Cited by PubMed: 26762569 DOI: 10.1002/cbic.201500532 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.084 Å)

Structure validation