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5OGL
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BU of 5ogl by Molmil
Structure of bacterial oligosaccharyltransferase PglB in complex with an acceptor peptide and an lipid-linked oligosaccharide analog
Descriptor: MANGANESE (II) ION, SODIUM ION, Substrate mimicking peptide, ...
Authors:Napiorkowska, M, Boilevin, J, Sovdat, T, Darbre, T, Reymond, J.-L, Aebi, M, Locher, K.P.
Deposit date:2017-07-13
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase.
Nat. Struct. Mol. Biol., 24, 2017
5NO0
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BU of 5no0 by Molmil
Beta domain of human transcobalamin in apo form
Descriptor: GLYCEROL, Transcobalamin-2
Authors:Bloch, J.S, Locher, K.P.
Deposit date:2017-04-10
Release date:2017-09-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structure of the human transcobalamin beta domain in four distinct states.
PLoS ONE, 12, 2017
5NRP
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BU of 5nrp by Molmil
Beta domain of human transcobalamin bound to cobinamide
Descriptor: COB(II)INAMIDE, CYANIDE ION, Transcobalamin-2
Authors:Bloch, J.S, Locher, K.P.
Deposit date:2017-04-25
Release date:2017-09-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.569 Å)
Cite:Structure of the human transcobalamin beta domain in four distinct states.
PLoS ONE, 12, 2017
5OVW
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BU of 5ovw by Molmil
Nanobody-bound BtuF, the vitamin B12 binding protein in Escherichia coli
Descriptor: GLYCEROL, Nanobody, Vitamin B12-binding protein
Authors:Mireku, S.A, Sauer, M.M, Glockshuber, R, Locher, K.P.
Deposit date:2017-08-30
Release date:2017-11-08
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.653 Å)
Cite:Structural basis of nanobody-mediated blocking of BtuF, the cognate substrate-binding protein of the Escherichia coli vitamin B12 transporter BtuCD.
Sci Rep, 7, 2017
7NIU
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BU of 7niu by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (apo-inward-open conformation)
Descriptor: 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, CHOLESTEROL, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2021-02-14
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NIV
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BU of 7niv by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation)
Descriptor: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment light chain, CHOLESTEROL, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2021-02-14
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NIW
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BU of 7niw by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation)
Descriptor: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2021-02-14
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NEZ
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BU of 7nez by Molmil
Structure of topotecan-bound ABCG2
Descriptor: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ...
Authors:Kowal, J, Locher, K, Ni, D, Stahlberg, H.
Deposit date:2021-02-05
Release date:2021-04-21
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
J.Mol.Biol., 433, 2021
7NFD
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BU of 7nfd by Molmil
Structure of mitoxantrone-bound ABCG2
Descriptor: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ...
Authors:Kowal, J, Locher, K, Ni, D, Stahlberg, H.
Deposit date:2021-02-06
Release date:2021-04-21
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
J.Mol.Biol., 433, 2021
7NEQ
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BU of 7neq by Molmil
Structure of tariquidar-bound ABCG2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ...
Authors:Kowal, J, Locher, K.
Deposit date:2021-02-04
Release date:2021-04-21
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
J.Mol.Biol., 433, 2021
6QEE
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BU of 6qee by Molmil
Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ABCB1HM-EQ, ...
Authors:Alam, A.
Deposit date:2019-01-07
Release date:2019-02-27
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.
Science, 363, 2019

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