5TPK
 
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3W9S
 | | Crystal Structure Analysis of the N-terminal Receiver domain of Response Regulator PmrA | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, OmpR family response regulator in two-component regulatory system with BasS | | Authors: | Chen, C, Luo, S. | | Deposit date: | 2013-04-15 | | Release date: | 2013-07-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella Pneumoniae
J.Biol.Chem., 288, 2013
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2LNM
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6A4C
 | | Solution structure of MXAN_0049 | | Descriptor: | Uncharacterized protein MXAN_0049 | | Authors: | Chen, C, Feng, Y. | | Deposit date: | 2018-06-19 | | Release date: | 2019-06-19 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure of MXAN_0049
To Be Published
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3QYM
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6A2V
 | | Crystal structure of Hcp protein | | Descriptor: | Type VI secretion system tube protein Hcp | | Authors: | Jobichen, C, Sivaraman, J. | | Deposit date: | 2018-06-13 | | Release date: | 2018-09-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.588 Å) | | Cite: | Structural basis for the pathogenesis of Campylobacter jejuni Hcp1, a structural and effector protein of the Type VI Secretion System.
FEBS J., 285, 2018
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4PLQ
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4RUD
 | | Crystal structure of a three finger toxin | | Descriptor: | Three-finger toxin 3b, ZINC ION | | Authors: | Jobichen, C, Sivaraman, J. | | Deposit date: | 2014-11-18 | | Release date: | 2016-05-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
Br.J.Pharmacol., 177, 2020
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7C28
 | | Unusual quaternary structure of a homodimeric synergistic toxin from mamba snake venom | | Descriptor: | SULFATE ION, Synergistic-type venom protein S2C4 | | Authors: | Jobichen, C, Narumi, A, Sivaraman, J, Kini, R.M. | | Deposit date: | 2020-05-07 | | Release date: | 2020-10-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Unusual quaternary structure of a homodimeric synergistic-type toxin from mamba snake venom defines its molecular evolution.
Biochem.J., 477, 2020
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4ZQY
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3VTS
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3TVD
 | | Crystal Structure of Mouse RhoA-GTP complex | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | | Authors: | Swaminathan, K, Pal, K, Jobichen, C. | | Deposit date: | 2011-09-20 | | Release date: | 2012-10-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.989 Å) | | Cite: | Crystal structure of mouse RhoA:GTPgammaS complex in a centered lattice.
J.Struct.Funct.Genom., 13, 2012
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5XWR
 | | Crystal Structure of RBBP4-peptide complex | | Descriptor: | Histone-binding protein RBBP4, MET-SER-ARG-ARG-LYS-GLN-ALA-LYS-PRO-GLN-HIS-ILE | | Authors: | Jobichen, C, Lui, B.H, Daniel, G.T, Sivaraman, J. | | Deposit date: | 2017-06-30 | | Release date: | 2018-07-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7DEY
 | | Structure of Dicer from Pichia stipitis | | Descriptor: | RNase III | | Authors: | Jobichen, C, Jingru, C. | | Deposit date: | 2020-11-05 | | Release date: | 2021-05-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.897 Å) | | Cite: | Structural and mechanistic insight into stem-loop RNA processing by yeast Pichia stipitis Dicer.
Protein Sci., 30, 2021
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7FCF
 | | Crystal structure of T6SS Hcp protein | | Descriptor: | Fimbrial protein | | Authors: | Jobichen, C, Sivaraman, J. | | Deposit date: | 2021-07-14 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Bacterial antagonism of Chromobacterium haemolyticum and characterization of its putative type VI secretion system.
Res.Microbiol., 173, 2022
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1M58
 | | Solution Structure of Cytotoxic RC-RNase2 | | Descriptor: | RC-RNase2 ribonuclease | | Authors: | Hsu, C.-H, Liao, Y.-D, Wu, S.-H, Chen, C. | | Deposit date: | 2002-07-09 | | Release date: | 2003-01-09 | | Last modified: | 2022-12-21 | | Method: | SOLUTION NMR | | Cite: | 1H, 15N and 13C resonance assignments and secondary structure determination of the RC-RNase 2 from oocytes of bullfrog Rana catesbeiana.
J.Biomol.Nmr, 19, 2001
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6KOR
 | | Crystal structure of the RRM domain of SYNCRIP | | Descriptor: | Heterogeneous nuclear ribonucleoprotein Q | | Authors: | Chen, Y, Chan, J, Chen, W, Jobichen, C. | | Deposit date: | 2019-08-12 | | Release date: | 2020-01-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | SYNCRIP, a new player in pri-let-7a processing.
Rna, 26, 2020
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5EU8
 | | Structure of FIPV main protease in complex with dual inhibitors | | Descriptor: | 1,2-ETHANEDIOL, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, ZINC ION, ... | | Authors: | Wang, F, Chen, C, Liu, X, Yang, K, Xu, X, Yang, H. | | Deposit date: | 2015-11-18 | | Release date: | 2015-12-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.447 Å) | | Cite: | Crystal Structure of Feline Infectious Peritonitis Virus Main Protease in Complex with Synergetic Dual Inhibitors
J.Virol., 90, 2015
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2RQX
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5DIB
 | | 2.25 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) Y450L point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-08-31 | | Release date: | 2015-10-14 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | 2.25 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) Y450L point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289
To Be Published
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4ZXU
 | | 2.85 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/P449M double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289 | | Descriptor: | Betaine-aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-05-20 | | Release date: | 2015-06-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | 2.85 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/P449M double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289.
To be Published
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5EYU
 | | 1.72 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-11-25 | | Release date: | 2015-12-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | 1.72 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289
To Be Published
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1BC4
 | | THE SOLUTION STRUCTURE OF A CYTOTOXIC RIBONUCLEASE FROM THE OOCYTES OF RANA CATESBEIANA (BULLFROG), NMR, 15 STRUCTURES | | Descriptor: | RIBONUCLEASE | | Authors: | Chang, C.-F, Chen, C, Chen, Y.-C, Hom, K, Huang, R.-F, Huang, T. | | Deposit date: | 1998-05-05 | | Release date: | 1998-10-14 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana (bullfrog).
J.Mol.Biol., 283, 1998
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5EZ4
 | | 2.11 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-11-26 | | Release date: | 2015-12-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | 2.11 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289
To Be Published
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6KZ6
 | | Crystal structure of ASFV dUTPase | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R, MAGNESIUM ION | | Authors: | Guo, Y, Chen, C, Li, G.B, Cao, L, Wang, C.W. | | Deposit date: | 2019-09-23 | | Release date: | 2019-11-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.187 Å) | | Cite: | Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family.
J.Virol., 94, 2020
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