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Structure of UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase from Acinetobacter baumannii
Descriptor:	1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2015-04-28
Release date:	2015-05-20
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structure of UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase from Acinetobacter baumannii to be published

4Z04

Crystal structure of a probable lactoylglutathione lyase from Brucella melitensis in complex with glutathione
Descriptor:	(4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, GLUTATHIONE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2015-03-25
Release date:	2015-04-22
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Crystal structure of a probable lactoylglutathione lyase from Brucella melitensis in complex with glutathione to be published

4O2D

Crystal structure of aspartyl-tRNA synthetase from Mycobacterium smegmatis with bound aspartic acid
Descriptor:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ASPARTIC ACID, Aspartate--tRNA ligase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-12-17
Release date:	2014-01-22
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4ONY

Crystal structure of a ABC transporter, periplasmic substrate-binding protein from Brucella melitensis
Descriptor:	1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, CHLORIDE ION, Extracellular solute-binding protein family 5, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2014-01-29
Release date:	2014-06-18
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal structure of a ABC transporter, periplasmic substrate-binding protein from Brucella melitensis To be Published

3MD0

Crystal structure of arginine/ornithine transport system ATPase from Mycobacterium tuberculosis bound to GDP (a RAS-like GTPase superfamily protein)
Descriptor:	Arginine/ornithine transport system ATPase, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-03-29
Release date:	2010-04-21
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. J.Struct.Funct.Genom., 16, 2015

4E51

Crystal structure of a histidyl-tRNA synthetase HisRS from Burkholderia thailandensis bound to histidine
Descriptor:	HISTIDINE, Histidine--tRNA ligase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-03-13
Release date:	2012-03-28
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017

3TK1

Crystal structure of a MeaB and Rv1496 ortholog from Mycobacterium thermoresistible bound to GDP
Descriptor:	CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Membrane ATPase/protein kinase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2011-08-25
Release date:	2011-10-05
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. J.Struct.Funct.Genom., 16, 2015

4G6Z

Crystal structure of a glutamyl-tRNA synthetase GluRS from Burkholderia thailandensis bound to L-glutamate
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLUTAMIC ACID, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-07-19
Release date:	2012-08-01
Last modified:	2023-12-06
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017

4GHK

X-ray Crystal Structure of Gamma-glutamyl phosphate reductase from Burkholderia thailandensis
Descriptor:	Gamma-glutamyl phosphate reductase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-08-07
Release date:	2012-12-26
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4GK6

X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus
Descriptor:	CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-08-10
Release date:	2012-12-19
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4GRI

Crystal structure of a glutamyl-tRNA synthetase GluRS from Borrelia burgdorferi bound to glutamic acid and zinc
Descriptor:	CHLORIDE ION, GLUTAMIC ACID, Glutamate--tRNA ligase, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-08-24
Release date:	2012-09-05
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017

4H3Y

Crystal structure of an asymmetric dimer of a tRNA (guanine-(N(1)-)-methyltransferase from Burkholderia phymatum bound to S-adenosyl homocystein in one half-site
Descriptor:	CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-09-14
Release date:	2012-10-03
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4H51

Crystal structure of a putative Aspartate Aminotransferase from Leishmania major Friedlin
Descriptor:	1,2-ETHANEDIOL, Aspartate aminotransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-09-18
Release date:	2012-10-10
Last modified:	2015-05-20
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015

4H4G

Crystal Structure of (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase from Burkholderia thailandensis E264
Descriptor:	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Authors:	Craig, T.K, Edwards, T.E, Staker, B, Stewart, L, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-09-17
Release date:	2012-10-03
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4H3Z

Crystal structure of a symmetric dimer of a tRNA (guanine-(N(1)-)-methyltransferase from Burkholderia phymatum bound to S-adenosyl homocystein in both half-sites
Descriptor:	CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-09-14
Release date:	2012-10-03
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4HDT

Crystal structure of a Carnitinyl-CoA dehydratase from Mycobacterium thermoresistibile
Descriptor:	3-hydroxyisobutyryl-CoA hydrolase, ACETATE ION, CHLORIDE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-10-02
Release date:	2012-10-10
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4GT1

Crystal structure of a MeaB- and MMAA-like GTPase from Mycobacterium tuberculosis bound to 2'-deoxyguanosine diphosphate
Descriptor:	2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Probable GTPase Rv1496/MT1543, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-08-28
Release date:	2012-09-05
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. J.Struct.Funct.Genom., 16, 2015

4HR3

Structure of a putative acyl-CoA dehydrogenase from Mycobacterium abscessus
Descriptor:	FLAVIN-ADENINE DINUCLEOTIDE, Putative acyl-CoA dehydrogenase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-10-26
Release date:	2012-11-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4I1V

Crystal structure of a dephospho-CoA kinase from Burkholderia vietnamiensis bound to ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Dephospho-CoA kinase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-11-21
Release date:	2013-01-09
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Crystal structure of a dephospho-CoA kinase from Burkholderia vietnamiensis bound to ADP TO BE PUBLISHED

4I1Y

The structure of Cysteine synthase from Mycobacterium ulcerans Agy99
Descriptor:	CHLORIDE ION, Cysteine synthase, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-11-21
Release date:	2012-12-26
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4IG6

Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
Descriptor:	CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-12-16
Release date:	2012-12-26
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine TO BE PUBLISHED

4IJN

Crystal structure of an acetate kinase from Mycobacterium smegmatis bound to AMP and sulfate
Descriptor:	1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Acetate kinase, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-12-21
Release date:	2013-01-16
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4IV6

X-ray crystal structure of an isovaleryl-CoA dehydrogenase from Mycobacterium smegmatis
Descriptor:	Acyl-CoA dehydrogenase FadE3, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-01-22
Release date:	2013-03-20
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

6M94

Monophosphorylated pSer33 b-Catenin peptide bound to b-TrCP/Skp1 Complex
Descriptor:	Catenin beta-1, DIMETHYL SULFOXIDE, F-box/WD repeat-containing protein 1A, ...
Authors:	Simonetta, K.R, Clifton, M.C, Walter, R.L, Ranieri, G.M, Carter, J.J.
Deposit date:	2018-08-22
Release date:	2019-04-03
Last modified:	2019-04-10
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun, 10, 2019

6M91

Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-103094 ternary complex
Descriptor:	3-({4-[(2,6-dichlorophenyl)sulfanyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonyl}amino)benzoic acid, CHLORIDE ION, Catenin beta-1, ...
Authors:	Simonetta, K.R, Clifton, M.C, Walter, R.L, Ranieri, G.M, Carter, J.J.
Deposit date:	2018-08-22
Release date:	2019-04-03
Last modified:	2019-04-10
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun, 10, 2019

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