5SZP
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![BU of 5szp by Molmil](/molmil-images/mine/5szp) | Protocadherin Gamma B7 extracellular cadherin domains 1-4 P21 crystal form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protocadherin Gamma B7, ... | Authors: | Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L. | Deposit date: | 2016-08-14 | Release date: | 2016-10-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | gamma-Protocadherin structural diversity and functional implications. Elife, 5, 2016
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1PIH
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![BU of 1pih by Molmil](/molmil-images/mine/1pih) | THE THREE DIMENSIONAL STRUCTURE OF THE PARAMAGNETIC PROTEIN HIPIP I FROM E.HALOPHILA THROUGH NUCLEAR MAGNETIC RESONANCE | Descriptor: | HIGH POTENTIAL IRON SULFUR PROTEIN, IRON/SULFUR CLUSTER | Authors: | Banci, L, Bertini, I, Eltis, L.D, Felli, I, Kastrau, D.H.W, Luchinat, C, Piccioli, M, Pierattelli, R, Smith, M. | Deposit date: | 1994-08-03 | Release date: | 1994-12-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The three-dimensional structure in solution of the paramagnetic high-potential iron-sulfur protein I from Ectothiorhodospira halophila through nuclear magnetic resonance. Eur.J.Biochem., 225, 1994
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1PIJ
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![BU of 1pij by Molmil](/molmil-images/mine/1pij) | THE THREE DIMENSIONAL STRUCTURE OF THE PARAMAGNETIC PROTEIN HIPIP I FROM E.HALOPHILA THROUGH NUCLEAR MAGNETIC RESONANCE | Descriptor: | HIGH POTENTIAL IRON SULFUR PROTEIN, IRON/SULFUR CLUSTER | Authors: | Banci, L, Bertini, I, Eltis, L.D, Felli, I.C, Kastrau, D.H.W, Luchinat, C, Piccioli, M, Pierattelli, R, Smith, M. | Deposit date: | 1994-11-11 | Release date: | 1995-02-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The three-dimensional structure in solution of the paramagnetic high-potential iron-sulfur protein I from Ectothiorhodospira halophila through nuclear magnetic resonance. Eur.J.Biochem., 225, 1994
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7QSY
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![BU of 7qsy by Molmil](/molmil-images/mine/7qsy) | Non-obligately L8S8-complex forming RubisCO derived from ancestral sequence reconstruction and rational engineering in L8S8 complex | Descriptor: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, RubisCO large subunit, ... | Authors: | Zarzycki, J, Schulz, L, Erb, T.J, Hochberg, G.K.A. | Deposit date: | 2022-01-14 | Release date: | 2022-10-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Science, 378, 2022
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1I2M
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![BU of 1i2m by Molmil](/molmil-images/mine/1i2m) | RAN-RCC1-SO4 COMPLEX | Descriptor: | GTP-BINDING NUCLEAR PROTEIN RAN, REGULATOR OF CHROMOSOME CONDENSATION 1, SULFATE ION | Authors: | Renault, L, Kuhlmann, J, Henkel, A, Wittinghofer, A. | Deposit date: | 2001-02-11 | Release date: | 2001-05-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell(Cambridge,Mass.), 105, 2001
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5T2D
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![BU of 5t2d by Molmil](/molmil-images/mine/5t2d) | mPI3Kd IN COMPLEX WITH 7j | Descriptor: | 4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]-~{N},~{N}-dimethyl-pyrazole-1-sulfonamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Authors: | Petersen, J, Terstige, I, Perry, M, Svensson, T, Tyrchan, C, Lindmark, H, Oster, L. | Deposit date: | 2016-08-23 | Release date: | 2017-04-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Discovery of triazole aminopyrazines as a highly potent and selective series of PI3K delta inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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5T2M
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![BU of 5t2m by Molmil](/molmil-images/mine/5t2m) | mPI3Kd IN COMPLEX WITH 7m | Descriptor: | 4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]benzamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Authors: | Petersen, J, Terstige, I, Perry, M, Svensson, T, Tyrchan, C, Lindmark, H, Oster, L. | Deposit date: | 2016-08-23 | Release date: | 2017-04-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery of triazole aminopyrazines as a highly potent and selective series of PI3K delta inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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7QSZ
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![BU of 7qsz by Molmil](/molmil-images/mine/7qsz) | Non-obligately L8S8-complex forming RubisCO derived from ancestral sequence reconstruction and rational engineering in L8 complex with substitution e170N | Descriptor: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, RubisCO large subunit | Authors: | Zarzycki, J, Schulz, L, Erb, T.J, Hochberg, G.K.A. | Deposit date: | 2022-01-14 | Release date: | 2022-10-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Science, 378, 2022
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1PQX
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![BU of 1pqx by Molmil](/molmil-images/mine/1pqx) | Solution NMR Structure of Staphylococcus aureus protein SAV1430. Northeast Structural Genomics Consortium Target ZR18. | Descriptor: | conserved hypothetical protein | Authors: | Baran, M.C, Aramini, J.M, Xiao, R, Huang, Y.J, Acton, T.B, Shih, L, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-06-19 | Release date: | 2004-09-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Strucutre of the Hypothetical Staphylococcus Aureus protein SAV1430. Northest Strucutral Genomics Consortium target ZR18 To be Published
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1I5G
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![BU of 1i5g by Molmil](/molmil-images/mine/1i5g) | TRYPAREDOXIN II COMPLEXED WITH GLUTATHIONYLSPERMIDINE | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUTATHIONYLSPERMIDINE, TRYPAREDOXIN II | Authors: | Hofmann, B, Budde, H, Bruns, K, Guerrero, S.A, Kalisz, H.M, Menge, U, Montemartini, M, Nogoceke, E, Steinert, P, Wissing, J.B, Flohe, L, Hecht, H.-J. | Deposit date: | 2001-02-27 | Release date: | 2001-03-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structures of tryparedoxins revealing interaction with trypanothione. Biol.Chem., 382, 2001
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1IC8
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![BU of 1ic8 by Molmil](/molmil-images/mine/1ic8) | HEPATOCYTE NUCLEAR FACTOR 1A BOUND TO DNA : MODY3 GENE PRODUCT | Descriptor: | 5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*G)-3', HEPATOCYTE NUCLEAR FACTOR 1-ALPHA | Authors: | Chi, Y.-I, Frantz, J.D, Oh, B.-C, Hansen, L, Dhe-Paganon, S, Shoelson, S.E. | Deposit date: | 2001-03-30 | Release date: | 2002-11-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Diabetes mutations delineate an
atypical POU domains in HNF1-Alpha Mol.Cell, 10, 2002
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5U6K
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![BU of 5u6k by Molmil](/molmil-images/mine/5u6k) | |
7RQC
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![BU of 7rqc by Molmil](/molmil-images/mine/7rqc) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site MFI-tripeptidyl-tRNA analog ACCA-IFM at 2.50A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | Deposit date: | 2021-08-06 | Release date: | 2022-01-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
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6FWL
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![BU of 6fwl by Molmil](/molmil-images/mine/6fwl) | Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex alpha-Glc-1,3-(1,2-anhydro-carba-mannose) | Descriptor: | (1~{S},2~{S},3~{R},4~{R},6~{R})-4-(hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2,3-diol, ACETATE ION, Glycosyl hydrolase family 71, ... | Authors: | Sobala, L.F, Speciale, G, Hakki, Z, Fernandes, P.Z, Raich, L, Rojas-Cervellera, V, Bennet, A, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Lu, D, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. | Deposit date: | 2018-03-06 | Release date: | 2019-09-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | An Epoxide Intermediate in Glycosidase Catalysis. Acs Cent.Sci., 6, 2020
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6FWP
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![BU of 6fwp by Molmil](/molmil-images/mine/6fwp) | Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-1,3-mannobiose and alpha-1,2-mannobiose | Descriptor: | ACETATE ION, Glycosyl hydrolase family 71, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, ... | Authors: | Sobala, L.F, Speciale, G, Hakki, Z, Fernandes, P.Z, Raich, L, Rojas-Cervellera, V, Bennet, A, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Lu, D, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. | Deposit date: | 2018-03-06 | Release date: | 2019-09-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | An Epoxide Intermediate in Glycosidase Catalysis. Acs Cent.Sci., 6, 2020
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1I93
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![BU of 1i93 by Molmil](/molmil-images/mine/1i93) | NMR ENSEMBLE OF ION-SELECTIVE LIGAND D16 FOR PLATELET INTEGRIN ALPHAIIB-BETA3 | Descriptor: | ION-SELECTIVE LIGAND D16 | Authors: | Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N. | Deposit date: | 2001-03-17 | Release date: | 2002-07-10 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3. J.Biol.Chem., 277, 2002
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7R2V
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![BU of 7r2v by Molmil](/molmil-images/mine/7r2v) | Structure of nsp14 from SARS-CoV-2 in complex with SAH | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Proofreading exoribonuclease nsp14, ... | Authors: | Czarna, A, Plewka, J, Kresik, L, Matsuda, A, Abdulkarim, K, Robinson, C, OByrne, S, Cunningham, F, Georgiou, I, Pachota, M, Popowicz, G.M, Wyatt, P.G, Dubin, G, Pyrc, K. | Deposit date: | 2022-02-06 | Release date: | 2022-03-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity. Structure, 30, 2022
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5UC9
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![BU of 5uc9 by Molmil](/molmil-images/mine/5uc9) | |
6G5J
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![BU of 6g5j by Molmil](/molmil-images/mine/6g5j) | Secreted phospholipase A2 type X in complex with ligand | Descriptor: | (3~{R})-3-[3-[2-aminocarbonyl-6-(trifluoromethyloxy)indol-1-yl]phenyl]butanoic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sandmark, J, Oster, L. | Deposit date: | 2018-03-29 | Release date: | 2018-09-05 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid. ACS Med Chem Lett, 9, 2018
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5TR7
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![BU of 5tr7 by Molmil](/molmil-images/mine/5tr7) | Crystal structure of a putative D-alanyl-D-alanine carboxypeptidase from Vibrio cholerae O1 biovar eltor str. N16961 | Descriptor: | D-alanyl-D-alanine carboxypeptidase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Shatsman, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-10-25 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of a putative D-alanyl-D-alanine carboxypeptidase from Vibrio cholerae O1 biovar eltor str. N16961 To Be Published
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1I3U
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![BU of 1i3u by Molmil](/molmil-images/mine/1i3u) | THREE-DIMENSIONAL STRUCTURE OF A LLAMA VHH DOMAIN COMPLEXED WITH THE DYE RR1 | Descriptor: | 5-(4,6-DIAMINO-[1,3,5]TRIAZIN-2-YLAMINO)-4-HYDROXY-3-(2-SULFO-PHENYLAZO)-NAPHTHALENE-2,7-DISULFONIC ACID, ANTIBODY VHH LAMA DOMAIN, SULFATE ION | Authors: | Spinelli, S, Tegoni, M, Frenken, L, van Vliet, C, Cambillau, C. | Deposit date: | 2001-02-16 | Release date: | 2001-08-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Lateral recognition of a dye hapten by a llama VHH domain. J.Mol.Biol., 311, 2001
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7RQB
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![BU of 7rqb by Molmil](/molmil-images/mine/7rqb) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site MAI-tripeptidyl-tRNA analog ACCA-IAM at 2.45A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | Deposit date: | 2021-08-06 | Release date: | 2022-01-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
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1I8V
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![BU of 1i8v by Molmil](/molmil-images/mine/1i8v) | CRYSTAL STRUCTURE OF RNASE SA Y80F MUTANT | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE SA, SULFATE ION | Authors: | Sevcik, J, Urbanikova, L. | Deposit date: | 2001-03-16 | Release date: | 2001-09-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Tyrosine hydrogen bonds make a large contribution to protein stability. J.Mol.Biol., 312, 2001
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5TVV
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![BU of 5tvv by Molmil](/molmil-images/mine/5tvv) | Computationally Designed Fentanyl Binder - Fen49* Apo | Descriptor: | Endo-1,4-beta-xylanase A, POTASSIUM ION | Authors: | Bick, M.J, Greisen, P.J, Morey, K.J, Antunes, A.S, La, D, Sankaran, B, Reymond, L, Johnsson, K, Medford, J.I, Baker, D. | Deposit date: | 2016-11-10 | Release date: | 2017-10-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Computational design of environmental sensors for the potent opioid fentanyl. Elife, 6, 2017
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1I6N
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![BU of 1i6n by Molmil](/molmil-images/mine/1i6n) | 1.8 A Crystal structure of IOLI protein with a binding zinc atom | Descriptor: | IOLI PROTEIN, ZINC ION | Authors: | Zhang, R.G, Dementiva, I, Collart, F, Quaite-Randall, E, Joachimiak, A, Alkire, R, Maltsev, N, Korolev, O, Dieckman, L, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-03-02 | Release date: | 2002-03-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Bacillus subtilis ioli shows endonuclase IV fold with altered Zn binding. Proteins, 48, 2002
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