4PPI
| Crystal structure of Bcl-xL hexamer | Descriptor: | Bcl-2-like protein 1, GLYCEROL | Authors: | Sreekanth, R, Yoon, H.S. | Deposit date: | 2014-02-27 | Release date: | 2015-03-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.851 Å) | Cite: | Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport Sci Rep, 5, 2015
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4LX4
| Crystal Structure Determination of Pseudomonas stutzeri endoglucanase Cel5A using a Twinned Data Set | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoglucanase(Endo-1,4-beta-glucanase)protein | Authors: | Dutoit, R, Delsaute, M, Berlemont, R, Van Elder, D, Galleni, M, Bauvois, C. | Deposit date: | 2013-07-29 | Release date: | 2014-07-30 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.556 Å) | Cite: | Crystal structure determination of Pseudomonas stutzeri A1501 endoglucanase Cel5A: the search for a molecular basis for glycosynthesis in GH5_5 enzymes. Acta Crystallogr D Struct Biol, 75, 2019
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7W12
| Complex structure of alginate lyase AlyB-OU02 with G9 | Descriptor: | Alginate lyase, SULFATE ION, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid | Authors: | Liu, W.Z, Lyu, Q.Q, Zhang, K.K. | Deposit date: | 2021-11-19 | Release date: | 2022-11-16 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Determination of oligosaccharide product distributions of PL7 alginate lyases by their structural elements. Commun Biol, 5, 2022
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7W16
| Complex structure of alginate lyase AlyV with M8 | Descriptor: | GLYCEROL, alginate lyase, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Liu, W.Z, Lyu, Q.Q, Li, Z.J, Zhang, K.K. | Deposit date: | 2021-11-19 | Release date: | 2022-08-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Determination of oligosaccharide product distributions of PL7 alginate lyases by their structural elements. Commun Biol, 5, 2022
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7W13
| Complex structure of alginate lyase PyAly with M8 | Descriptor: | Alginate lyase, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Liu, W.Z, Lyu, Q.Q, Li, Z.J, Zhang, K.K. | Deposit date: | 2021-11-19 | Release date: | 2022-08-17 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Determination of oligosaccharide product distributions of PL7 alginate lyases by their structural elements. Commun Biol, 5, 2022
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7DL0
| The mutant E310G/A314Y of 3,5-DAHDHcca complex with NADPH | Descriptor: | 1,2-ETHANEDIOL, 3,5-diaminohexanoate dehydrogenase, CHLORIDE ION, ... | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-25 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL7
| The wild-type structure of 3,5-DAHDHcca | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,5-diaminohexanoate dehydrogenase, ... | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-26 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.30065823 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL1
| The mutant E310G/G323S structure of 3,5-DAHDHcca complex with NADPH | Descriptor: | 3,5-diaminohexanoate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-25 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL3
| The structure of 3,5-DAHDHcca complex with NADPH | Descriptor: | 3,5-diaminohexanoate dehydrogenase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-25 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84606934 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7WCM
| Cryo-EM structure of GPR119-Gs Complex with small molecule agonist MBX-2982 | Descriptor: | 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole, Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Qiao, A.N, Wu, S, Ye, S. | Deposit date: | 2021-12-20 | Release date: | 2022-12-21 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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7WCN
| Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453 | Descriptor: | Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Qiao, A.N, Wu, S, Ye, S. | Deposit date: | 2021-12-20 | Release date: | 2022-12-21 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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3ED0
| Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin | Descriptor: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, BENZAMIDINE, ... | Authors: | Zhang, L, Zhang, H, Liu, W, Guo, Y, Shen, X, Jiang, H. | Deposit date: | 2008-09-02 | Release date: | 2009-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization BMC MICROBIOL., 9, 2009
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7WGI
| Crystal structure of AflSQS from Aspergillus flavus | Descriptor: | INDOLE, PHOSPHATE ION, Squalene synthase | Authors: | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2021-12-28 | Release date: | 2022-11-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins. Acs Omega, 7, 2022
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7WGH
| Crystal structure of AflSQS from Aspergillus flavus in complex with FSPP | Descriptor: | PHOSPHATE ION, PYROPHOSPHATE 2-, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | Authors: | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2021-12-28 | Release date: | 2022-11-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins. Acs Omega, 7, 2022
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7W18
| Complex structure of alginate lyase PyAly with M5 | Descriptor: | Alginate lyase, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Liu, W.Z, Lyu, Q.Q, Zhang, K.K. | Deposit date: | 2021-11-19 | Release date: | 2022-08-17 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Determination of oligosaccharide product distributions of PL7 alginate lyases by their structural elements. Commun Biol, 5, 2022
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7VQ6
| Structure of a specialized glyoxalase from Gossypium hirsutum | Descriptor: | Lactoylglutathione lyase, NICKEL (II) ION | Authors: | Li, H, Hu, Y.M, Dai, L.H, Chen, C.C, Huang, J.W, Liu, W.D, Guo, R.T. | Deposit date: | 2021-10-19 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Crystal structure and biochemical analysis of the specialized deoxynivalenol-detoxifying glyoxalase SPG from Gossypium hirsutum. Int.J.Biol.Macromol., 200, 2022
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2XP2
| Structure of the Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (PF-02341066) | Descriptor: | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, TYROSINE-PROTEIN KINASE RECEPTOR | Authors: | McTigue, M, Deng, Y, Liu, W, Brooun, A, Timofeevski, S, Marrone, T, Cui, J.J. | Deposit date: | 2010-08-24 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure Based Drug Design of Crizotinib (Pf-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal-Epithelial Transition Factor (C-met) Kinase and Anaplastic Lymphoma Kinase (Alk). J.Med.Chem, 54, 2011
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5XKN
| Crystal structure of plant receptor ERL2 in complexe with EPFL4 | Descriptor: | EPIDERMAL PATTERNING FACTOR-like protein 4, LRR receptor-like serine/threonine-protein kinase ERL2 | Authors: | Chai, J, Lin, G. | Deposit date: | 2017-05-08 | Release date: | 2019-01-23 | Method: | X-RAY DIFFRACTION (3.651 Å) | Cite: | A receptor-like protein acts as a specificity switch for the regulation of stomatal development. Genes Dev., 31, 2017
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5XJO
| Plant receptor ERL1-TMM in complex with peptide EPF1 | Descriptor: | LRR receptor-like serine/threonine-protein kinase ERL1, Protein EPIDERMAL PATTERNING FACTOR 1, Protein TOO MANY MOUTHS | Authors: | Chai, J, Lin, G, Zhang, L, Han, Z, Shpak, E.D, Yang, X. | Deposit date: | 2017-05-03 | Release date: | 2019-01-23 | Method: | X-RAY DIFFRACTION (2.626 Å) | Cite: | A receptor-like protein acts as a specificity switch for the regulation of stomatal development. Genes Dev., 31, 2017
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7VWP
| Structure of the flavin-dependent monooxygenase FlsO1 from the biosynthesis of fluostatinsin | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FlsO1, PHOSPHATE ION, ... | Authors: | Zhang, Y, Yang, C, Zhang, L, Zhang, C. | Deposit date: | 2021-11-11 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation Nat Commun, 13, 2022
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5Y9W
| Crystal 1 for AtLURE1.2-AtPRK6LRR | Descriptor: | Pollen receptor-like kinase 6, Protein LURE 1.2, SULFATE ION | Authors: | Chai, J, Zhang, X. | Deposit date: | 2017-08-28 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.847 Å) | Cite: | Structural basis for receptor recognition of pollen tube attraction peptides. Nat Commun, 8, 2017
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5YGF
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5YAH
| Crystal 2 for AtLURE1.2-AtPRK6LRR | Descriptor: | Pollen receptor-like kinase 6, Protein LURE 1.2 | Authors: | Chai, J, Zhang, X. | Deposit date: | 2017-08-31 | Release date: | 2018-04-11 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Structural basis for receptor recognition of pollen tube attraction peptides. Nat Commun, 8, 2017
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5YGD
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6JQ9
| Crystal structure of a lyase from Alteromonas sp. | Descriptor: | CALCIUM ION, SULFATE ION, Short ulvan lyase | Authors: | Qin, H.M, Guo, Q.Q. | Deposit date: | 2019-03-29 | Release date: | 2020-04-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Biochemical characterization and structural analysis of ulvan lyase from marine Alteromonas sp. reveals the basis for its salt tolerance. Int.J.Biol.Macromol., 147, 2020
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