4GZT
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![BU of 4gzt by Molmil](/molmil-images/mine/4gzt) | N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2012-09-06 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
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4GZP
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![BU of 4gzp by Molmil](/molmil-images/mine/4gzp) | N2 Neuraminidase of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2012-09-06 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
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4FI8
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![BU of 4fi8 by Molmil](/molmil-images/mine/4fi8) | Kinetic Stabilization of transthyretin through covalent modification of K15 by 4-bromo-3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide | Descriptor: | 4-bromo-3-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride, Transthyretin | Authors: | Connelly, S, Grimster, N, Wilson, I.A, Kelly, J.W. | Deposit date: | 2012-06-08 | Release date: | 2013-02-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate. J.Am.Chem.Soc., 135, 2013
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4FNK
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![BU of 4fnk by Molmil](/molmil-images/mine/4fnk) | |
4FQK
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![BU of 4fqk by Molmil](/molmil-images/mine/4fqk) | Influenza B/Brisbane/60/2008 hemagglutinin Fab CR8059 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8059 Heavy Chain, ... | Authors: | Dreyfus, C, Laursen, N.S, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (5.65 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FNL
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![BU of 4fnl by Molmil](/molmil-images/mine/4fnl) | |
4FQM
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![BU of 4fqm by Molmil](/molmil-images/mine/4fqm) | Structure of B/Brisbane/60/2008 Influenza Hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | Authors: | Dreyfus, C, Laursen, N.S, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FQR
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![BU of 4fqr by Molmil](/molmil-images/mine/4fqr) | |
4GH9
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![BU of 4gh9 by Molmil](/molmil-images/mine/4gh9) | Crystal structure of Marburg virus VP35 RNA binding domain | Descriptor: | ACETATE ION, Polymerase cofactor VP35 | Authors: | Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O. | Deposit date: | 2012-08-07 | Release date: | 2012-08-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism. Plos Pathog., 8, 2012
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4FQL
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![BU of 4fql by Molmil](/molmil-images/mine/4fql) | Influenza B HA Antibody (Fab) CR8033 | Descriptor: | monoclonal antibody CR8033 heavy chain, monoclonal antibody CR8033 light chain | Authors: | Dreyfus, C, Laursen, N.S, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FQV
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![BU of 4fqv by Molmil](/molmil-images/mine/4fqv) | Crystal structure of broadly neutralizing antibody CR9114 bound to H7 influenza hemagglutinin | Descriptor: | Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ... | Authors: | Ekiert, D.C, Dreyfus, C, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (5.75 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FI6
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![BU of 4fi6 by Molmil](/molmil-images/mine/4fi6) | Kinetic Stabilization of transthyretin through covalent modification of K15 by 3-(5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide | Descriptor: | 3-[5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride, Transthyretin | Authors: | Connelly, S, Grimster, N, Wilson, I.A, Kelly, J.W. | Deposit date: | 2012-06-08 | Release date: | 2013-02-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate. J.Am.Chem.Soc., 135, 2013
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4FQH
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![BU of 4fqh by Molmil](/molmil-images/mine/4fqh) | Crystal Structure of Fab CR9114 | Descriptor: | 1,2-ETHANEDIOL, NITRATE ION, antibody CR9114 heavy chain, ... | Authors: | Dreyfus, C, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4GXX
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![BU of 4gxx by Molmil](/molmil-images/mine/4gxx) | Crystal structure of the "avianized" 1918 influenza virus hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | Ekiert, D.C, Wilson, I.A. | Deposit date: | 2012-09-04 | Release date: | 2012-12-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8, 2012
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4GZO
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![BU of 4gzo by Molmil](/molmil-images/mine/4gzo) | N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with hepes | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2012-09-06 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
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4GZX
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![BU of 4gzx by Molmil](/molmil-images/mine/4gzx) | |
4GZS
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![BU of 4gzs by Molmil](/molmil-images/mine/4gzs) | N2 neuraminidase D151G mutant of a/Tanzania/205/2010 H3N2 in complex with hepes | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2012-09-06 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
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4FI7
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![BU of 4fi7 by Molmil](/molmil-images/mine/4fi7) | Kinetic Stabilization of transthyretin through covalent modification of K15 by 3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide | Descriptor: | 3-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride, Transthyretin | Authors: | Connelly, S, Grimster, N, Wilson, I.A, Kelly, J.W. | Deposit date: | 2012-06-08 | Release date: | 2013-02-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.402 Å) | Cite: | Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate. J.Am.Chem.Soc., 135, 2013
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4FP8
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![BU of 4fp8 by Molmil](/molmil-images/mine/4fp8) | |
4FQJ
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![BU of 4fqj by Molmil](/molmil-images/mine/4fqj) | Influenza B/Florida/4/2006 hemagglutinin Fab CR8071 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, antibody CR8071 heavy chain, ... | Authors: | Dreyfus, C, Laursen, N.S, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FQY
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![BU of 4fqy by Molmil](/molmil-images/mine/4fqy) | Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin | Descriptor: | Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ... | Authors: | Ekiert, D.C, Dreyfus, C, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (5.253 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FQI
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![BU of 4fqi by Molmil](/molmil-images/mine/4fqi) | |
4HFU
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![BU of 4hfu by Molmil](/molmil-images/mine/4hfu) | Crystal structure of Fab 8M2 in complex with a H2N2 influenza virus hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 8M2 heavy chain, Fab 8M2 light chain, ... | Authors: | Xu, R, Wilson, I.A. | Deposit date: | 2012-10-05 | Release date: | 2013-02-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.106 Å) | Cite: | A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nat.Struct.Mol.Biol., 20, 2013
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4GXU
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![BU of 4gxu by Molmil](/molmil-images/mine/4gxu) | |
4GZQ
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![BU of 4gzq by Molmil](/molmil-images/mine/4gzq) | |