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7MLC
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BU of 7mlc by Molmil
PYL10 bound to the ABA pan-antagonist 4a
Descriptor: 1-{2-[3,5-dicyclopropyl-4-(4-{[(quinoxaline-2-carbonyl)amino]methyl}-1H-1,2,3-triazol-1-yl)phenyl]acetamido}cyclohexane-1-carboxylic acid, Abscisic acid receptor PYL10, GLYCEROL
Authors:Peterson, F.C, Vaidya, A.S, Volkman, B.F, Cutler, S.R.
Deposit date:2021-04-28
Release date:2021-09-29
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MLD
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BU of 7mld by Molmil
PYL10 bound to the ABA pan-antagonist antabactin
Descriptor: Abscisic acid receptor PYL10, CITRIC ACID, antabactin
Authors:Peterson, F.C, Vaidya, A.S, Volkman, B.F, Cutler, S.R.
Deposit date:2021-04-28
Release date:2021-09-29
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.
Proc.Natl.Acad.Sci.USA, 118, 2021
8EY0
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BU of 8ey0 by Molmil
Structure of an orthogonal PYR1*:HAB1* chemical-induced dimerization module in complex with mandipropamid
Descriptor: (2S)-2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)ethanamide, Abscisic acid receptor PYR1, GLYCEROL, ...
Authors:Park, S.-Y, Volkman, B.F, Cutler, S.R, Peterson, F.C.
Deposit date:2022-10-26
Release date:2023-11-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity.
Nat.Chem.Biol., 20, 2024
8HMY
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BU of 8hmy by Molmil
Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex
Descriptor: Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ...
Authors:Zhang, X, Yang, F, Zhan, X, Shi, Y.
Deposit date:2022-12-06
Release date:2023-04-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
8HMZ
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BU of 8hmz by Molmil
Cryo-EM structure of the human post-catalytic TSEN/pre-tRNA complex
Descriptor: Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ...
Authors:Zhang, X, Yang, F, Zhan, X, Shi, Y.
Deposit date:2022-12-06
Release date:2023-04-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
7VPX
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BU of 7vpx by Molmil
The cryo-EM structure of the human pre-A complex
Descriptor: 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-10-18
Release date:2023-05-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
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