8EY0

Structure of an orthogonal PYR1:HAB1 chemical-induced dimerization module in complex with mandipropamid

Summary for 8EY0

Entry DOI	10.2210/pdb8ey0/pdb
Descriptor	Protein phosphatase 2C 16, Abscisic acid receptor PYR1, GLYCEROL, ... (5 entities in total)
Functional Keywords	pyr/pyl/rcar, pyr1, hab1, hormone receptor, plant protein, biosensor
Biological source	Arabidopsis thaliana (thale cress) More
Total number of polymer chains	2
Total formula weight	58111.59
Authors	Park, S.-Y.,Volkman, B.F.,Cutler, S.R.,Peterson, F.C. (deposition date: 2022-10-26, release date: 2023-11-08, Last modification date: 2024-01-10)
Primary citation	Park, S.Y.,Qiu, J.,Wei, S.,Peterson, F.C.,Beltran, J.,Medina-Cucurella, A.V.,Vaidya, A.S.,Xing, Z.,Volkman, B.F.,Nusinow, D.A.,Whitehead, T.A.,Wheeldon, I.,Cutler, S.R. An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity. Nat.Chem.Biol., 20:103-110, 2024 Cited by PubMed: 37872402 DOI: 10.1038/s41589-023-01447-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation