8EY0
Structure of an orthogonal PYR1*:HAB1* chemical-induced dimerization module in complex with mandipropamid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Protein phosphatase 2C 16 | polymer | 333 | 36901.3 | 1 | UniProt (Q9CAJ0) Pfam (PF00481) | Arabidopsis thaliana (thale cress) | AtPP2C16,AtP2C-HA,Protein HYPERSENSITIVE TO ABA 1,Protein phosphatase 2C HAB1,PP2C HAB1 |
| 2 | B (A) | Abscisic acid receptor PYR1 | polymer | 181 | 20614.3 | 1 | UniProt (O49686) Pfam (PF03364) | Arabidopsis thaliana (thale cress) | ABI1-binding protein 6,Protein PYRABACTIN RESISTANCE 1,Regulatory components of ABA receptor 11 |
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | (2S)-2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)ethanamide | non-polymer | 411.9 | 1 | Chemie (3UZ) | |||
| 5 | F, G (B, A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
B: 179 - 511 (UniProt: Q9CAJ0)
A: 1 - 181 (UniProt: O49686)
| PDB | External Database | Details |
|---|---|---|
| Ala 199 | Arg 199 | conflict |
| Ala 204 | Asp 204 | conflict |
| Asp 322 | Ser 322 | conflict |
| Arg 393 | Val 393 | conflict |
| Ala 510 | Arg 510 | conflict |
| PDB | External Database | Details |
|---|---|---|
| His 58 | Tyr 58 | conflict |
| Arg 59 | Lys 59 | conflict |
| Ile 81 | Val 81 | conflict |
| Ala 108 | Phe 108 | conflict |
| Gly 122 | Ser 122 | conflict |
| Ile 158 | Met 158 | conflict |
| Val 159 | Phe 159 | conflict |
| Val 160 | Ala 160 | conflict |
| Asp 162 | Thr 162 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57515.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 596.1 | |
| All* | Total formula weight | 58111.6 |
