6WQ2
| Cryo-EM of the S. islandicus filamentous virus, SIFV | Descriptor: | A-DNA, Structural protein MCP1, Structural protein MCP2 | Authors: | Wang, F, Baquero, D.P, Su, Z, Zheng, W, Prangishvili, D, Krupovic, M, Egelman, E.H. | Deposit date: | 2020-04-28 | Release date: | 2020-07-29 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WL9
| Cryo-EM of Form 2 like peptide filament, Form2a | Descriptor: | peptide Form2a | Authors: | Wang, F, Beltran, L.C, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WKX
| Cryo-EM of Form 1 related peptide filament, 15-10-3 | Descriptor: | peptide 15-10-3 | Authors: | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-17 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL7
| Cryo-EM of Form 2 like peptide filament, 29-20-2 | Descriptor: | peptide 29-20-2 | Authors: | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | Deposit date: | 2020-04-18 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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7KHD
| Human GITR-GITRL complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18 | Authors: | Wang, F, Chau, B, West, S.M, Strop, P. | Deposit date: | 2020-10-21 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.956102 Å) | Cite: | Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions. Nat Commun, 12, 2021
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7KHX
| Mouse GITR-GITRL complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, ... | Authors: | Wang, F, Chau, B, West, S.M, Strop, P. | Deposit date: | 2020-10-22 | Release date: | 2021-03-03 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.20569849 Å) | Cite: | Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions. Nat Commun, 12, 2021
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2PFC
| Structure of Mycobacterium tuberculosis Rv0098 | Descriptor: | Hypothetical protein Rv0098/MT0107, PALMITIC ACID | Authors: | Wang, F, Sacchettini, J.C. | Deposit date: | 2007-04-04 | Release date: | 2008-04-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem.Biol., 14, 2007
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5JR3
| Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with SAH and 4-methylumbelliferone | Descriptor: | 7-hydroxy-4-methyl-2H-chromen-2-one, Carminomycin 4-O-methyltransferase DnrK, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Wang, F, Johnson, B.R, Huber, T.D, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2016-05-05 | Release date: | 2016-06-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with SAH and 4-methylumbelliferone (to be published) To Be Published
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6EF8
| Cryo-EM of the OmcS nanowires from Geobacter sulfurreducens | Descriptor: | C-type cytochrome OmcS, HEME C | Authors: | Wang, F, Gu, Y, Egelman, E.H, Malvankar, N.S. | Deposit date: | 2018-08-16 | Release date: | 2019-04-10 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers. Cell, 177, 2019
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8WF7
| The Crystal Structure of integrase from Biortus | Descriptor: | ACETATE ION, Integrase, SULFATE ION | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | Deposit date: | 2023-09-19 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Crystal Structure of integrase from Biortus To Be Published
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8WD2
| The Crystal Structure of p53 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, PHOSPHATE ION, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y. | Deposit date: | 2023-09-14 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Crystal Structure of p53 from Biortus. To Be Published
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8WFG
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8WF4
| The Crystal Structure of RSK1 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, Ribosomal protein S6 kinase alpha-1 | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Li, J. | Deposit date: | 2023-09-19 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The Crystal Structure of RSK1 from Biortus. To Be Published
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8WFF
| The Crystal Structure of LYN from Biortus. | Descriptor: | CHLORIDE ION, CITRATE ANION, Tyrosine-protein kinase Lyn | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y. | Deposit date: | 2023-09-19 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The Crystal Structure of LYN from Biortus. To Be Published
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8WFY
| The Crystal Structure of SHP2 from Biortus. | Descriptor: | 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | Deposit date: | 2023-09-20 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of SHP2 from Biortus. To Be Published
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8WD3
| The Crystal Structure of JMJD2A(M1-L359) from Biortus. | Descriptor: | Lysine-specific demethylase 4A, NICKEL (II) ION, ZINC ION | Authors: | Wang, F, Cheng, W, Lv, Z, Ju, C, Bao, C. | Deposit date: | 2023-09-14 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Crystal Structure of JMJD2A(M1-L359) from Biortus. To Be Published
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8WFQ
| The Crystal Structure of RALDH1 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Aldehyde dehydrogenase 1A1 | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Shen, Z. | Deposit date: | 2023-09-20 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The Crystal Structure of RALDH1 from Biortus. To Be Published
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8WFE
| The Crystal Structure of PPARg from Biortus. | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor gamma | Authors: | Wang, F, Cheng, W, Lv, Z, Guo, S, Lin, D. | Deposit date: | 2023-09-19 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Crystal Structure of PPARg from Biortus. To Be Published
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8WFR
| The Crystal Structure of PCSK9 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y. | Deposit date: | 2023-09-20 | Release date: | 2023-11-22 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Crystal Structure of PCSK9 from Biortus. To Be Published
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2QEF
| X-ray structure of 7-deaza-dG and Z3dU modified duplex CGCGAATXCZCG | Descriptor: | DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*(ZDU)P*DCP*(7GU)P*DCP*DG)-3') | Authors: | Wang, F, Li, F, Ganguly, M, Marky, L.A, Gold, B, Egli, M, Stone, M.P. | Deposit date: | 2007-06-25 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. Biochemistry, 47, 2008
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2QEG
| B-DNA with 7-deaza-dG modification | Descriptor: | DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*(7GU)P*DCP*DG)-3') | Authors: | Wang, F, Li, F, Ganguly, M, Marky, L.A, Gold, B, Egli, M, Stone, M.P. | Deposit date: | 2007-06-25 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. Biochemistry, 47, 2008
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7TGG
| Cryo-EM structure of PilA-N and PilA-C from Geobacter sulfurreducens | Descriptor: | Geopilin domain 1 protein, Geopilin domain 2 protein | Authors: | Wang, F, Mustafa, K, Chan, C.H, Joshi, K, Bond, D.R, Hochbaum, A.I, Egelman, E.H. | Deposit date: | 2022-01-07 | Release date: | 2022-02-23 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of an extracellular Geobacter OmcE cytochrome filament reveals tetrahaem packing. Nat Microbiol, 7, 2022
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7TFS
| Cryo-EM of the OmcE nanowires from Geobacter sulfurreducens | Descriptor: | Cytochrome c, HEME C | Authors: | Wang, F, Mustafa, K, Chan, C.H, Joshi, K, Hochbaum, A.I, Bond, D.R, Egelman, E.H. | Deposit date: | 2022-01-07 | Release date: | 2022-05-04 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of an extracellular Geobacter OmcE cytochrome filament reveals tetrahaem packing. Nat Microbiol, 7, 2022
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4ZAH
| Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12 | Descriptor: | [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3,4-bis(oxidanyl)oxan-2-yl] hydrogen phosphate, dTDP-4-amino-4,6-dideoxygalactose transaminase | Authors: | Wang, F, Singh, S, Cao, H, Xu, W, Miller, M.D, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-04-13 | Release date: | 2015-04-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. Acs Chem.Biol., 10, 2015
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7RO4
| Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 3 | Descriptor: | major capsid protein | Authors: | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | Deposit date: | 2021-07-30 | Release date: | 2022-03-30 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome. Cell, 185, 2022
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