2X7A
| Structural basis of HIV-1 tethering to membranes by the Bst2-tetherin ectodomain | Descriptor: | BONE MARROW STROMAL ANTIGEN 2, CHLORIDE ION, GLYCEROL, ... | Authors: | Natrajan, G, McCarthy, A.A, Weissenhorn, W. | Deposit date: | 2010-02-25 | Release date: | 2010-04-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Structural Basis of HIV-1 Tethering to Membranes by the Bst-2/Tetherin Ectodomain. Cell Host Microbe, 7, 2010
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2XMT
| Copper chaperone Atx1 from Synechocystis PCC6803 (Cu1 form) | Descriptor: | COPPER (I) ION, SSR2857 PROTEIN | Authors: | Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C. | Deposit date: | 2010-07-29 | Release date: | 2010-08-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Visualizing the Metal-Binding Versatility of Copper Trafficking Sites . Biochemistry, 49, 2010
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2XZS
| Death associated protein kinase 1 residues 1-312 | Descriptor: | DEATH ASSOCIATED KINASE 1, MAGNESIUM ION | Authors: | Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J. | Deposit date: | 2010-11-29 | Release date: | 2011-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Death-Associated Protein Kinase Activity is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites. Structure, 24, 2016
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2XMU
| Copper chaperone Atx1 from Synechocystis PCC6803 (Cu2 form) | Descriptor: | COPPER (I) ION, SSR2857 PROTEIN | Authors: | Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C. | Deposit date: | 2010-07-29 | Release date: | 2010-08-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Visualizing the Metal-Binding Versatility of Copper Trafficking Sites . Biochemistry, 49, 2010
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2V70
| Third LRR domain of human Slit2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SLIT HOMOLOG 2 PROTEIN N-PRODUCT | Authors: | Morlot, C, Cusack, S, McCarthy, A.A. | Deposit date: | 2007-07-24 | Release date: | 2007-08-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Production of Slit2 Lrr Domains in Mammalian Cells for Structural Studies and the Structure of Human Slit2 Domain 3. Acta Crystallogr.,Sect.D, 63, 2007
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2Y0A
| Structure of DAPK1 construct residues 1-304 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DEATH-ASSOCIATED PROTEIN KINASE 1 | Authors: | Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J. | Deposit date: | 2010-12-01 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Library-Based Construct Screening of Death-Associated Protein Kinase 1 Identifies the Minimal Calmodulin Interaction Region and Autoinhibitory Conformation of the Catalytic Domain To be Published
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2XMM
| Visualising the Metal-binding Versatility of Copper Trafficking Sites: H61Y Atx1 side-to-side | Descriptor: | CHLORIDE ION, COPPER (II) ION, SODIUM ION, ... | Authors: | Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C. | Deposit date: | 2010-07-28 | Release date: | 2010-08-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Visualizing the Metal-Binding Versatility of Copper Trafficking Sites . Biochemistry, 49, 2010
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2XMW
| PacS, N-terminal domain, from Synechocystis PCC6803 | Descriptor: | CATION-TRANSPORTING ATPASE PACS, COPPER (I) ION | Authors: | Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C. | Deposit date: | 2010-07-29 | Release date: | 2010-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Visualizing the Metal-Binding Versatility of Copper Trafficking Sites . Biochemistry, 49, 2010
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2XMJ
| Visualising the Metal-binding Versatility of Copper Trafficking Sites: Atx1 side-to-side (aerobic) | Descriptor: | CHLORIDE ION, COPPER (II) ION, SODIUM ION, ... | Authors: | Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C. | Deposit date: | 2010-07-28 | Release date: | 2010-08-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Visualizing the Metal-Binding Versatility of Copper Trafficking Sites . Biochemistry, 49, 2010
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4G0B
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4P1Z
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4PRQ
| CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH SCLX4 AT 1.72 A RESOLUTION | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, HEXAETHYLENE GLYCOL, ... | Authors: | McGovern, R.E, McCarthy, A.A, Crowley, P.B. | Deposit date: | 2014-03-06 | Release date: | 2014-09-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Protein assembly mediated by sulfonatocalix[4]arene. Chem.Commun.(Camb.), 50, 2014
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5FIQ
| Exonuclease domain-containing 1 (Exd1) in the native conformation | Descriptor: | EXD1 | Authors: | Yang, Z, Chen, K.M, Pandey, R.R, Homolka, D, Reuter, M, Rodino Janeiro, B.K, Sachidanandam, R, Fauvarque, M.O, McCarthy, A.A, Pillai, R.S. | Deposit date: | 2015-10-01 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Piwi Slicing and Exd1 Drive Biogenesis of Nuclear Pirnas from Cytosolic Targets of the Mouse Pirna Pathway Mol.Cell, 61, 2016
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5FIS
| Exonuclease domain-containing 1 (Exd1) in the Gd bound conformation | Descriptor: | EXD1, GADOLINIUM ATOM | Authors: | Yang, Z, Chen, K.M, Pandey, R.R, Homolka, D, Reuter, M, Rodino Janeiro, B.K, Sachidanandam, R, Fauvarque, M.O, McCarthy, A.A, Pillai, R.S. | Deposit date: | 2015-10-02 | Release date: | 2015-12-23 | Last modified: | 2016-01-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Piwi Slicing and Exd1 Drive Biogenesis of Nuclear Pirnas from Cytosolic Targets of the Mouse Pirna Pathway Mol.Cell, 61, 2016
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5UNA
| Fragment of 7SK snRNA methylphosphate capping enzyme | Descriptor: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, unidentified peptide section/fragment | Authors: | Wu, H, Tempel, W, Dombrovski, L, McCarthy, A.A, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2017-01-30 | Release date: | 2017-03-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Fragment of 7SK snRNA methylphosphate capping enzyme To Be Published
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1H5Y
| HisF protein from Pyrobaculum aerophilum | Descriptor: | GLYCEROL, HISF, PHOSPHATE ION | Authors: | Banfield, M.J, Lott, J.S, McCarthy, A.A, Baker, E.N. | Deposit date: | 2001-05-31 | Release date: | 2001-06-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Hisf, a Histidine Biosynthetic Protein from Pyrobaculum Aerophilum Acta Crystallogr.,Sect.D, 57, 2001
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4D82
| Metallosphera sedula Vps4 crystal structure | Descriptor: | AAA ATPase, central domain protein, ADENOSINE-5'-DIPHOSPHATE | Authors: | Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P. | Deposit date: | 2014-12-02 | Release date: | 2015-11-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly. Nat.Commun., 6, 2015
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4D80
| Metallosphera sedula Vps4 crystal structure | Descriptor: | AAA ATPASE, CENTRAL DOMAIN PROTEIN | Authors: | Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P. | Deposit date: | 2014-12-02 | Release date: | 2015-10-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly. Nat.Commun., 6, 2015
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4D81
| Metallosphera sedula Vps4 crystal structure | Descriptor: | AAA ATPase, central domain protein, ADENOSINE-5'-DIPHOSPHATE | Authors: | Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P. | Deposit date: | 2014-12-02 | Release date: | 2015-11-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly. Nat.Commun., 6, 2015
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8C3P
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8C4W
| Crystal structure of rat autotaxin and compound MEY-002 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5,7-bis(oxidanyl)-2-[1-(phenylmethyl)indol-3-yl]chromen-4-one, 7alpha-hydroxycholesterol, ... | Authors: | Eymery, M.C, McCarthy, A.A. | Deposit date: | 2023-01-05 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids. Eur.J.Med.Chem., 263, 2023
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8C3O
| Crystal structure of autotaxin gamma and compound MEY-003 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5,7-bis(oxidanyl)-2-(1-pentylindol-3-yl)chromen-4-one, 7alpha-hydroxycholesterol, ... | Authors: | Eymery, M.C, McCarthy, A.A. | Deposit date: | 2022-12-27 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids. Eur.J.Med.Chem., 263, 2023
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8C7R
| Crystal structure of rat autotaxin and compound MEY-003 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5,7-bis(oxidanyl)-2-(1-pentylindol-3-yl)chromen-4-one, 7alpha-hydroxycholesterol, ... | Authors: | Eymery, M.C, McCarthy, A.A. | Deposit date: | 2023-01-17 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids. Eur.J.Med.Chem., 263, 2023
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4A2Q
| Structure of duck RIG-I tandem CARDs and helicase domain | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-28 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4A2P
| Structure of duck RIG-I helicase domain | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-28 | Release date: | 2011-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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