8JLF
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLE
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8JLG
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLC
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLH
| Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLI
| Cryo-EM structure of SV2A dimer in complex levetiracetam | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, Synaptic vesicle glycoprotein 2A | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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7EXW
| GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with alpha-L-arabinofuranosylamide | Descriptor: | 2-bromanyl-N-[(2R,3R,4R,5S}-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]ethanamide, Non-reducing end beta-L-arabinofuranosidase, ZINC ION | Authors: | Sawano, K, Arakawa, T, Yamada, C, Fujita, K, Fushinobu, S. | Deposit date: | 2021-05-28 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Substrate complex structure, active site labeling and catalytic role of the zinc ion in cysteine glycosidase. Glycobiology, 32, 2022
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7EXU
| GH127 beta-L-arabinofuranosidase HypBA1 E322Q mutant complexed with p-nitrophenyl beta-L-arabinofuranoside | Descriptor: | (2S,3R,4R,5R)-2-(hydroxymethyl)-5-(4-nitrophenoxy)oxolane-3,4-diol, Non-reducing end beta-L-arabinofuranosidase, ZINC ION | Authors: | Maruyama, S, Arakawa, T, Yamada, C, Fujita, K, Fushinobu, S. | Deposit date: | 2021-05-28 | Release date: | 2021-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substrate complex structure, active site labeling and catalytic role of the zinc ion in cysteine glycosidase. Glycobiology, 32, 2022
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7EXV
| GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with beta-L-arabinofuranoylamide | Descriptor: | 2-bromanyl-N-[(2S,3R,4R,5S)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]ethanamide, Non-reducing end beta-L-arabinofuranosidase, ZINC ION | Authors: | Sawano, K, Arakawa, T, Yamada, C, Fujita, K, Fushinobu, S. | Deposit date: | 2021-05-28 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Substrate complex structure, active site labeling and catalytic role of the zinc ion in cysteine glycosidase. Glycobiology, 32, 2022
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7F4V
| Cryo-EM structure of a primordial cyanobacterial photosystem I | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | Authors: | Kato, K, Hamaguchi, T, Nagao, R, Kawakami, K, Yonekura, K, Shen, J.R. | Deposit date: | 2021-06-21 | Release date: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.04 Å) | Cite: | Structural basis for the absence of low-energy chlorophylls responsible for photoprotection from a primitive cyanobacterial PSI Biorxiv, 2022
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8JS9
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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7F5S
| human delta-METTL18 60S ribosome | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Takahashi, M, Kashiwagi, K, Ito, T. | Deposit date: | 2021-06-22 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance. Elife, 11, 2022
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8JS8
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8K77
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and brivaracetam | Descriptor: | (2S)-2-[(4R)-2-oxidanylidene-4-propyl-pyrrolidin-1-yl]butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-07-26 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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3VQJ
| Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase | Descriptor: | Carbonyl sulfide hydrolase, SODIUM ION, ZINC ION | Authors: | Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. | Deposit date: | 2012-03-24 | Release date: | 2013-02-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
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3VRK
| Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase / Thiocyanate complex | Descriptor: | Carbonyl sulfide hydrolase, SODIUM ION, THIOCYANATE ION, ... | Authors: | Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. | Deposit date: | 2012-04-11 | Release date: | 2013-02-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
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2ZA0
| Crystal structure of mouse glyoxalase I complexed with methyl-gerfelin | Descriptor: | Glyoxalase I, ZINC ION, methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate | Authors: | Okumura, H, Kawatani, M, Osada, H. | Deposit date: | 2007-09-26 | Release date: | 2008-08-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I Proc.Natl.Acad.Sci.Usa, 105, 2008
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2DXB
| Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers | Descriptor: | COBALT (III) ION, PHOSPHATE ION, Thiocyanate hydrolase subunit alpha, ... | Authors: | Arakawa, T, Kawano, Y, Katayama, Y, Yohda, M, Odaka, M. | Deposit date: | 2006-08-25 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification J.Am.Chem.Soc., 131, 2009
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2DXC
| Recombinant thiocyanate hydrolase, fully-matured form | Descriptor: | COBALT (III) ION, L(+)-TARTARIC ACID, Thiocyanate hydrolase subunit alpha, ... | Authors: | Arakawa, T, Kawano, Y, Katayama, Y, Yohda, M, Odaka, M. | Deposit date: | 2006-08-25 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification J.Am.Chem.Soc., 131, 2009
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2E7S
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5XW6
| Crystal structure of the chicken ATP-gated P2X7 receptor channel in the presence of competitive antagonist TNP-ATP at 3.1 Angstroms | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE | Authors: | Kasuya, G, Hattori, M, Nureki, O. | Deposit date: | 2017-06-29 | Release date: | 2017-10-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel Nat Commun, 8, 2017
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5XVR
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5ZHS
| Crystal structure of OsD14 in complex with covalently bound KK052 | Descriptor: | (4-phenylpiperazin-1-yl)(1H-1,2,3-triazol-1-yl)methanone, Strigolactone esterase D14 | Authors: | Hirabayashi, K, Miyakawa, T, Tanokura, M. | Deposit date: | 2018-03-13 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses. Mol Plant, 12, 2019
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5XI8
| Structure and function of the TPR domain | Descriptor: | Beta-barrel assembly-enhancing protease | Authors: | Tanaka, Y, Tsukazaki, T. | Deposit date: | 2017-04-26 | Release date: | 2017-10-18 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The TPR domain of BepA is required for productive interaction with substrate proteins and the beta-barrel assembly machinery complex. Mol. Microbiol., 106, 2017
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5ZHT
| Crystal structure of OsD14 in complex with covalently bound KK073 | Descriptor: | (1H-1,2,3-triazol-1-yl){4-[4-(trifluoromethyl)phenyl]piperazin-1-yl}methanone, Strigolactone esterase D14 | Authors: | Hirabayashi, K, Miyakawa, T, Tanokura, M. | Deposit date: | 2018-03-13 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.532 Å) | Cite: | Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses. Mol Plant, 12, 2019
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