7AG7
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7AG1
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7AG6
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7AGK
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![BU of 7agk by Molmil](/molmil-images/mine/7agk) | Crystal structure of E. coli SF kinase (YihV) in complex with product sulfofructose phosphate (SFP) | Descriptor: | Sulfofructose kinase, [(2~{S},3~{S},4~{S},5~{R})-3,4,5-tris(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]methanesulfonic acid | Authors: | Sharma, M, Davies, G.J. | Deposit date: | 2020-09-22 | Release date: | 2021-04-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis. Acs Cent.Sci., 7, 2021
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5Y3T
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![BU of 5y3t by Molmil](/molmil-images/mine/5y3t) | Crystal structure of hetero-trimeric core of LUBAC: HOIP double-UBA complexed with HOIL-1L UBL and SHARPIN UBL | Descriptor: | E3 ubiquitin-protein ligase RNF31, GLYCEROL, RanBP-type and C3HC4-type zinc finger-containing protein 1, ... | Authors: | Tokunaga, A, Fujita, H, Ariyoshi, M, Ohki, I, Tochio, H, Iwai, K, Shirakawa, M. | Deposit date: | 2017-07-31 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization. Cell Rep, 23, 2018
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5YY0
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![BU of 5yy0 by Molmil](/molmil-images/mine/5yy0) | Crystal structure of the HyhL-HypA complex (form II) | Descriptor: | Cytosolic NiFe-hydrogenase, alpha subunit, Probable hydrogenase nickel incorporation protein HypA, ... | Authors: | Kwon, S, Watanabe, S, Nishitani, Y, Miki, K. | Deposit date: | 2017-12-07 | Release date: | 2018-06-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.243 Å) | Cite: | Crystal structures of a [NiFe] hydrogenase large subunit HyhL in an immature state in complex with a Ni chaperone HypA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5YXY
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![BU of 5yxy by Molmil](/molmil-images/mine/5yxy) | Crystal structure of the HyhL-HypA complex (form I) | Descriptor: | Cytosolic NiFe-hydrogenase, alpha subunit, Probable hydrogenase nickel incorporation protein HypA, ... | Authors: | Kwon, S, Watanabe, S, Nishitani, Y, Miki, K. | Deposit date: | 2017-12-07 | Release date: | 2018-06-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.299 Å) | Cite: | Crystal structures of a [NiFe] hydrogenase large subunit HyhL in an immature state in complex with a Ni chaperone HypA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7D1C
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![BU of 7d1c by Molmil](/molmil-images/mine/7d1c) | Crystal structure of mouse Cryptochrome 1 in complex with compound TH303 | Descriptor: | Cryptochrome-1, N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-4-(phenylcarbonyl)benzamide | Authors: | Miller, S.A, Hirota, T. | Deposit date: | 2020-09-14 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock. J.Am.Chem.Soc., 143, 2021
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7D19
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2Z5E
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![BU of 2z5e by Molmil](/molmil-images/mine/2z5e) | Crystal Structure of Proteasome Assembling Chaperone 3 | Descriptor: | Proteasome Assembling Chaperone 3 | Authors: | Okamoto, K, Kurimoto, E, Sakata, E, Suzuki, A, Yamane, T, Hirano, Y, Murata, S, Tanaka, K, Kato, K. | Deposit date: | 2007-07-06 | Release date: | 2008-02-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes Nat.Struct.Mol.Biol., 15, 2008
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2Z9S
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![BU of 2z9s by Molmil](/molmil-images/mine/2z9s) | Crystal Structure Analysis of rat HBP23/Peroxiredoxin I, Cys52Ser mutant | Descriptor: | Peroxiredoxin-1 | Authors: | Matsumura, T, Okamoto, K, Nishino, T, Abe, Y. | Deposit date: | 2007-09-25 | Release date: | 2007-11-20 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Dimer-Oligomer Interconversion of Wild-type and Mutant Rat 2-Cys Peroxiredoxin: DISULFIDE FORMATION AT DIMER-DIMER INTERFACES IS NOT ESSENTIAL FOR DECAMERIZATION J.Biol.Chem., 283, 2008
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4YDR
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3WXC
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![BU of 3wxc by Molmil](/molmil-images/mine/3wxc) | Crystal Structure of IMP-1 metallo-beta-lactamase complexed with a 3-aminophtalic acid inhibitor | Descriptor: | 3-(4-hydroxypiperidin-1-yl)benzene-1,2-dicarboxylic acid, Beta-lactamase, ZINC ION | Authors: | Saito, J, Watanabe, T, Yamada, M. | Deposit date: | 2014-07-29 | Release date: | 2014-10-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray crystallographic analysis of IMP-1 metallo-beta-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors Bioorg.Med.Chem.Lett., 24, 2014
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2ZUK
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![BU of 2zuk by Molmil](/molmil-images/mine/2zuk) | The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode) | Descriptor: | Alpha-amino-epsilon-caprolactam racemase, PYRIDOXAL-5'-PHOSPHATE, azepan-2-one | Authors: | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | Deposit date: | 2008-10-18 | Release date: | 2009-02-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | The novel structure of a pyridoxal 5'-phosphate-dependent fold-type I racemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae Biochemistry, 48, 2009
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1BK7
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![BU of 1bk7 by Molmil](/molmil-images/mine/1bk7) | RIBONUCLEASE MC1 FROM THE SEEDS OF BITTER GOURD | Descriptor: | PROTEIN (RIBONUCLEASE MC1) | Authors: | Nakagawa, A, Tanaka, I. | Deposit date: | 1998-07-15 | Release date: | 1999-07-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of a ribonuclease from the seeds of bitter gourd (Momordica charantia) at 1.75 A resolution. Biochim.Biophys.Acta, 1433, 1999
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3WIZ
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![BU of 3wiz by Molmil](/molmil-images/mine/3wiz) | Crystal structure of Bcl-xL in complex with compound 10 | Descriptor: | 7-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]carbamoyl}-2-methylphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid, Bcl-2-like protein 1, PHOSPHATE ION | Authors: | Sogabe, S, Igaki, S, Hayano, Y. | Deposit date: | 2013-09-26 | Release date: | 2013-11-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. J.Med.Chem., 56, 2013
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3WIY
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![BU of 3wiy by Molmil](/molmil-images/mine/3wiy) | Crystal structure of Mcl-1 in complex with compound 10 | Descriptor: | 7-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]carbamoyl}-2-methylphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Sogabe, S, Igaki, S, Hayano, Y. | Deposit date: | 2013-09-26 | Release date: | 2013-11-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. J.Med.Chem., 56, 2013
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6LUR
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3WIX
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![BU of 3wix by Molmil](/molmil-images/mine/3wix) | Crystal structure of Mcl-1 in complex with compound 4 | Descriptor: | 7-(4-carboxyphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Sogabe, S, Igaki, S, Hayano, Y. | Deposit date: | 2013-09-26 | Release date: | 2013-11-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. J.Med.Chem., 56, 2013
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3PCV
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![BU of 3pcv by Molmil](/molmil-images/mine/3pcv) | Crystal structure analysis of human leukotriene C4 synthase at 1.9 angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, DODECYL-BETA-D-MALTOSIDE, GLUTATHIONE, ... | Authors: | Saino, H, Ago, H, Miyano, M. | Deposit date: | 2010-10-22 | Release date: | 2011-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The catalytic architecture of leukotriene C4 synthase with two arginine residues J.Biol.Chem., 286, 2011
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5AVO
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1X12
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![BU of 1x12 by Molmil](/molmil-images/mine/1x12) | Structure of Mutant Pyrrolidone Carboxyl Peptidase (E192D) from a Hyperthermophile, Pyrococcus furiosus | Descriptor: | Pyrrolidone-carboxylate peptidase | Authors: | Kaushik, J.K, Yamagata, Y, Ogasahara, K, Yutani, K. | Deposit date: | 2005-03-31 | Release date: | 2006-06-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Completely buried, non-ion-paired glutamic acid contributes favorably to the conformational stability of pyrrolidone carboxyl peptidases from hyperthermophiles. Biochemistry, 45, 2006
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1X10
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![BU of 1x10 by Molmil](/molmil-images/mine/1x10) | Structure of Mutant Pyrrolidone Carboxyl Peptidase (E192A) from a Hyperthermophile, Pyrococcus furiosus | Descriptor: | Pyrrolidone-carboxylate peptidase | Authors: | Kaushik, J.K, Yamagata, Y, Ogasahara, K, Yutani, K. | Deposit date: | 2005-03-31 | Release date: | 2006-06-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Completely buried, non-ion-paired glutamic acid contributes favorably to the conformational stability of pyrrolidone carboxyl peptidases from hyperthermophiles. Biochemistry, 45, 2006
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2HAM
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![BU of 2ham by Molmil](/molmil-images/mine/2ham) | Crystal structure of VDR LBD complexed to 2alpha-propyl-calcitriol | Descriptor: | 2ALPHA-PROPYL-1ALPHA,25-DIHYDROXYVITAMIN D3, Vitamin D3 receptor | Authors: | Hourai, S, Rochel, N, Moras, D. | Deposit date: | 2006-06-13 | Release date: | 2006-08-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing a Water Channel near the A-Ring of Receptor-Bound 1alpha,25-Dihydroxyvitamin D3 with Selected 2alpha-Substituted Analogues J.Med.Chem., 49, 2006
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2HAR
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![BU of 2har by Molmil](/molmil-images/mine/2har) | Crystal structure of VDR LBD in complex with 2 alpha-(3-hydroxy-1-propoxy) calcitriol | Descriptor: | 2ALPHA-(3-HYDROXYPROPOXY)-1ALPHA,25-DIHYDROXYVITAMIN D3, Vitamin D3 receptor | Authors: | Hourai, S, Rochel, N, Moras, D. | Deposit date: | 2006-06-13 | Release date: | 2006-08-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing a Water Channel near the A-Ring of Receptor-Bound 1alpha,25-Dihydroxyvitamin D3 with Selected 2alpha-Substituted Analogues J.Med.Chem., 49, 2006
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