1GTV
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![BU of 1gtv by Molmil](/molmil-images/mine/1gtv) | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE-5'-DIPHOSPHATE (TDP) | Descriptor: | ACETATE ION, MAGNESIUM ION, SULFATE ION, ... | Authors: | Ursby, T, Weik, M, Fioravanti, E, Delarue, M, Goeldner, M, Bourgeois, D. | Deposit date: | 2002-01-21 | Release date: | 2002-03-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Cryophotolysis of Caged Compounds: A Technique for Trapping Intermediate States in Protein Crystals Acta Crystallogr.,Sect.D, 58, 2002
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8G5N
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![BU of 8g5n by Molmil](/molmil-images/mine/8g5n) | Cryo-EM structure of the Guide loop Engagement Complex (VI) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5I
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![BU of 8g5i by Molmil](/molmil-images/mine/8g5i) | Cryo-EM structure of the Mismatch Sensing Complex (I) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5K
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![BU of 8g5k by Molmil](/molmil-images/mine/8g5k) | Cryo-EM structure of the Wedge Alignment Complex (VIII) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5J
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![BU of 8g5j by Molmil](/molmil-images/mine/8g5j) | Cryo-EM structure of the Mismatch Uncoupling Complex (II) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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1UY0
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![BU of 1uy0 by Molmil](/molmil-images/mine/1uy0) | Carbohydrate binding module (CBM6cm-2) from Cellvibrio mixtus lichenase 5A in complex with glc-1,3-glc-1,4-glc-1,3-glc | Descriptor: | CALCIUM ION, CELLULASE B, CHLORIDE ION, ... | Authors: | Czjzek, M, Pires, V.M.R, Henshaw, J, Prates, J.A.M, Bolam, D, Henrissat, B, Gilbert, H.J. | Deposit date: | 2004-03-01 | Release date: | 2004-03-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The Crystal Structure of the Family 6 Carbohydrate Binding Module from Cellvibrio Mixtus Endoglucanase 5A in Complex with Oligosaccharides Reveals Two Distinct Binding Sites with Different Ligand Specificities J.Biol.Chem., 279, 2004
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8G5M
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![BU of 8g5m by Molmil](/molmil-images/mine/8g5m) | Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5L
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![BU of 8g5l by Molmil](/molmil-images/mine/8g5l) | Cryo-EM structure of the Primer Separation Complex (IX) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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6O3V
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![BU of 6o3v by Molmil](/molmil-images/mine/6o3v) | Crystal structure for RVA-VP3 | Descriptor: | 1,2-ETHANEDIOL, GUANOSINE-5'-MONOPHOSPHATE, Protein VP3, ... | Authors: | Kumar, D, Yu, X, Wang, Z, Hu, L, Prasad, V. | Deposit date: | 2019-02-27 | Release date: | 2020-03-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | 2.7 angstrom cryo-EM structure of rotavirus core protein VP3, a unique capping machine with a helicase activity. Sci Adv, 6, 2020
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8G5P
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![BU of 8g5p by Molmil](/molmil-images/mine/8g5p) | Cryo-EM structure of the Guide loop Engagement Complex (V) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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1HDJ
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![BU of 1hdj by Molmil](/molmil-images/mine/1hdj) | HUMAN HSP40 (HDJ-1), NMR | Descriptor: | HUMAN HSP40 | Authors: | Qian, Y.Q, Patel, D, Hartl, F.-U, Mccoll, D.J. | Deposit date: | 1996-05-09 | Release date: | 1996-11-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance solution structure of the human Hsp40 (HDJ-1) J-domain. J.Mol.Biol., 260, 1996
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8G5O
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![BU of 8g5o by Molmil](/molmil-images/mine/8g5o) | Cryo-EM structure of the Guide loop Engagement Complex (IV) of Human Mitochondrial DNA Polymerase Gamma | Descriptor: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | Authors: | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | Deposit date: | 2023-02-13 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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4X2F
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![BU of 4x2f by Molmil](/molmil-images/mine/4x2f) | Selection of fragments for kinase inhibitor design: decoration is key | Descriptor: | 4-amino-8-(4-aminophenyl)pyrido[2,3-d]pyrimidin-5(8H)-one, SULFATE ION, TGF-beta receptor type-1 | Authors: | Czodrowski, P, Hoelzemann, G, Barnickel, G, Greiner, H, Musil, D. | Deposit date: | 2014-11-26 | Release date: | 2015-10-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Selection of fragments for kinase inhibitor design: decoration is key. J.Med.Chem., 58, 2015
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4X2N
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![BU of 4x2n by Molmil](/molmil-images/mine/4x2n) | Selection of fragments for kinase inhibitor design: decoration is key | Descriptor: | SULFATE ION, TGF-beta receptor type-1 | Authors: | Czodrowski, P, Hoelzemann, G, Barnickel, G, Greiner, H, Musil, D. | Deposit date: | 2014-11-26 | Release date: | 2014-12-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Selection of fragments for kinase inhibitor design: decoration is key. J.Med.Chem., 58, 2015
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1HA9
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![BU of 1ha9 by Molmil](/molmil-images/mine/1ha9) | SOLUTION STRUCTURE OF THE SQUASH TRYPSIN INHIBITOR MCoTI-II, NMR, 30 STRUCTURES. | Descriptor: | TRYPSIN INHIBITOR II | Authors: | Heitz, A, Hernandez, J.-F, Gagnon, J, Hong, T.T, Pham, T.T.C, Nguyen, T.M, Le-Nguyen, D, Chiche, L. | Deposit date: | 2001-04-02 | Release date: | 2001-04-12 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Squash Trypsin Inhibitor Mcoti-II. A New Family for Cyclic Knottins Biochemistry, 40, 2001
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1GYO
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![BU of 1gyo by Molmil](/molmil-images/mine/1gyo) | Crystal structure of the di-tetraheme cytochrome c3 from Desulfovibrio gigas at 1.2 Angstrom resolution | Descriptor: | CYTOCHROME C3, A DIMERIC CLASS III C-TYPE CYTOCHROME, GLYCEROL, ... | Authors: | Aragao, D, Frazao, C, Sieker, L, Sheldrick, G.M, Legall, J, Carrondo, M.A. | Deposit date: | 2002-04-29 | Release date: | 2002-05-24 | Last modified: | 2023-03-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of Dimeric Cytochrome C3 from Desulfovibrio Gigas at 1.2 A Resolution Acta Crystallogr.,Sect.D, 59, 2003
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8DM3
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![BU of 8dm3 by Molmil](/molmil-images/mine/8dm3) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4A8 heavy chain, ... | Authors: | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | Deposit date: | 2022-07-08 | Release date: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.37 Å) | Cite: | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM2
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![BU of 8dm2 by Molmil](/molmil-images/mine/8dm2) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein (focused refinement of NTD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | Deposit date: | 2022-07-08 | Release date: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DXT
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![BU of 8dxt by Molmil](/molmil-images/mine/8dxt) | Fab arm of antibody GAR12 bound to the receptor binding domain of SARS-CoV-2. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab arm of antibody GAR12, Light chain of Fab arm of antibody GAR12, ... | Authors: | Langley, D.B, Christ, D, Henry, J.Y. | Deposit date: | 2022-08-03 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients. Nat Commun, 14, 2023
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4WYP
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![BU of 4wyp by Molmil](/molmil-images/mine/4wyp) | The crystal structure of the A109G mutant of RNase A in complex with 5'AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-17 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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6OAO
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![BU of 6oao by Molmil](/molmil-images/mine/6oao) | Structure of DBP in complex with human neutralizing antibody 092096 | Descriptor: | Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION | Authors: | Urusova, D, Tolia, N.H. | Deposit date: | 2019-03-18 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.497 Å) | Cite: | Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP. Nat Microbiol, 4, 2019
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6OFD
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![BU of 6ofd by Molmil](/molmil-images/mine/6ofd) | The crystal structure of octadecyloxy(naphthalen-1-yl)methylphosphonic acid in complex with red kidney bean purple acid phosphatase | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Feder, D, Schenk, G, Guddat, L.W, Hussein, W.M, McGeary, R.P, Kan, M.W. | Deposit date: | 2019-03-29 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis. Eur.J.Med.Chem., 182, 2019
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8DM4
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![BU of 8dm4 by Molmil](/molmil-images/mine/8dm4) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4A8 heavy chain, ... | Authors: | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | Deposit date: | 2022-07-08 | Release date: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8DM1
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![BU of 8dm1 by Molmil](/molmil-images/mine/8dm1) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | Deposit date: | 2022-07-08 | Release date: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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1GUV
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![BU of 1guv by Molmil](/molmil-images/mine/1guv) | Structure of human chitotriosidase | Descriptor: | 1,2-ETHANEDIOL, CHITOTRIOSIDASE | Authors: | Von Moeller, H, Houston, D, Boot, R.G, Aerts, J.M.F.G, Van Aalten, D.M.F. | Deposit date: | 2002-01-31 | Release date: | 2003-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of Human Chitotriosidase - Implications for Specific Inhibitor Design and Function of Mammalian Chitinase-Like Lectins J.Biol.Chem., 277, 2002
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