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6W9A
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BU of 6w9a by Molmil
RNF12 RING domain in complex with Ube2e2
Descriptor: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 E2, ...
Authors:Middleton, A.J, Day, C.L.
Deposit date:2020-03-22
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
7F02
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BU of 7f02 by Molmil
Cytochrome c-type biogenesis protein CcmABCD from E. coli
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ...
Authors:Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P.
Deposit date:2021-06-03
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
7F04
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BU of 7f04 by Molmil
Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP.
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ...
Authors:Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P.
Deposit date:2021-06-03
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
7F03
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BU of 7f03 by Molmil
Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ...
Authors:Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P.
Deposit date:2021-06-03
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
8HDS
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BU of 8hds by Molmil
Cyanophage Pam3 portal-adaptor
Descriptor: Pam3 adaptor protein, Pam3 portal protein
Authors:Yang, F, Jiang, Y.L, Zhou, C.Z.
Deposit date:2022-11-06
Release date:2023-01-18
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Fine structure and assembly pattern of a minimal myophage Pam3.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HDT
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BU of 8hdt by Molmil
Cyanophage Pam3 capsid asymmetric unit
Descriptor: Cement, Major capsid
Authors:Yang, F, Jiang, Y.L, Zhou, C.Z.
Deposit date:2022-11-06
Release date:2023-01-18
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Fine structure and assembly pattern of a minimal myophage Pam3.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HDW
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BU of 8hdw by Molmil
Cyanophage Pam3 Sheath-tube
Descriptor: Pam3 sheath protein, pam3 tube
Authors:Yang, F, Jiang, Y.L, Zhou, C.Z.
Deposit date:2022-11-06
Release date:2023-01-18
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Fine structure and assembly pattern of a minimal myophage Pam3.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HDR
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BU of 8hdr by Molmil
Cyanophage Pam3 neck
Descriptor: Pam3 adaptor protein, Pam3 connector protein, Pam3 sheath protein, ...
Authors:Yang, F, Jiang, Y.L, Zhou, C.Z.
Deposit date:2022-11-06
Release date:2023-02-01
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Fine structure and assembly pattern of a minimal myophage Pam3.
Proc.Natl.Acad.Sci.USA, 120, 2023
6A52
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BU of 6a52 by Molmil
Oxidase ChaP-H1
Descriptor: FE (II) ION, dioxidase ChaP-H1
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A5F
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BU of 6a5f by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of nargenicin
Descriptor: NgnD
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
8WYP
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BU of 8wyp by Molmil
High Resolution Crystal Structure of Brd4 BD-1 in Complex with a Novel Inhibitor Precursor
Descriptor: 3-bromanylimidazo[1,2-a]pyridin-6-amine, Bromodomain-containing protein 4
Authors:Liu, B, Ma, X.
Deposit date:2023-10-31
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:High resolution crystal structure of BRD4-BD1 in complex with a novel inhibitor precursor.
Biochem.Biophys.Res.Commun., 690, 2024
6A4X
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BU of 6a4x by Molmil
Oxidase ChaP-H2
Descriptor: Bleomycin resistance protein, FE (II) ION
Authors:Zhang, B, Wang, Y.S, Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A4Z
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BU of 6a4z by Molmil
Oxidase ChaP
Descriptor: ChaP protein, FE (II) ION
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A5G
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BU of 6a5g by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of streptoseomycin
Descriptor: [4+2] and [4+6] cyclase StmD
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A5H
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BU of 6a5h by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of unidentified natural product
Descriptor: 101015D
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.618 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
8IYX
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BU of 8iyx by Molmil
Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365
Descriptor: 1-[4-(3-chlorophenyl)phenyl]carbonyl-4-[2-(4-phenylmethoxyphenyl)ethanoylamino]piperidine-4-carboxylic acid, Probable G-protein coupled receptor 34,Probable G-protein coupled receptor 34,YL-365
Authors:Jia, G.W, Wang, X, Zhang, C.B, Dong, H.H, Su, Z.M.
Deposit date:2023-04-06
Release date:2024-03-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Proc.Natl.Acad.Sci.USA, 120, 2023
6LY4
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BU of 6ly4 by Molmil
The crystal structure of the BM3 mutant LG-23 in complex with testosterone
Descriptor: 1,2-ETHANEDIOL, Bifunctional cytochrome P450/NADPH--P450 reductase, IMIDAZOLE, ...
Authors:Peng, Y, Chen, J, Zhou, J, Li, A, ReetZ, M.T.
Deposit date:2020-02-13
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Regio- and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants.
Angew.Chem.Int.Ed.Engl., 59, 2020
5QBV
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BU of 5qbv by Molmil
Crystal structure of human Cathepsin-S with bound ligand
Descriptor: Cathepsin S, N-[2-chloro-5-(1-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-6-oxo-1,6-dihydropyridazin-3-yl)benzyl]benzamide
Authors:Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
Deposit date:2017-08-04
Release date:2017-12-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
7FE0
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BU of 7fe0 by Molmil
AvmM Catalyzes Macrocyclization in Alchivemycin A Biosynthesis
Descriptor: AvmM, CACODYLATE ION, CHLORIDE ION, ...
Authors:Zhang, B, Ge, H.M.
Deposit date:2021-07-19
Release date:2021-09-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:AvmM catalyses macrocyclization through dehydration/Michael-type addition in alchivemycin A biosynthesis.
Nat Commun, 13, 2022
5QBY
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BU of 5qby by Molmil
Crystal structure of human Cathepsin-S with bound ligand
Descriptor: Cathepsin S, N-[2-chloro-5-(1-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-6-oxo-1,6-dihydropyrimidin-5-yl)benzyl]-4-fluorobenzamide
Authors:Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
Deposit date:2017-08-04
Release date:2017-12-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
6CE0
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BU of 6ce0 by Molmil
Crystal structure of a HIV-1 clade B tier-3 isolate H078.14 UFO-BG Env trimer in complex with broadly neutralizing Fabs PGT124 and 35O22 at 4.6 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ...
Authors:Kumar, S, Sarkar, A, Wilson, I.A.
Deposit date:2018-02-09
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.602 Å)
Cite:HIV-1 vaccine design through minimizing envelope metastability.
Sci Adv, 4, 2018
7NYJ
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BU of 7nyj by Molmil
Structure of OBP1 from Varroa destructor, form P3<2>21
Descriptor: CALCIUM ION, Odorant Binding Protein 1 from Varoa destructor, form P3<2>21, ...
Authors:Cambillau, C, Amigues, B, Roussel, A, Leone, P, Gaubert, A, Pelosi, P.
Deposit date:2021-03-22
Release date:2021-07-07
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:A new non-classical fold of varroa odorant-binding proteins reveals a wide open internal cavity.
Sci Rep, 11, 2021
7NZA
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BU of 7nza by Molmil
Structure of OBP1 from Varroa destructor, form P2<1>
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Odorant Binding Protein from Varroa destructor, form P2<1>, ...
Authors:Cambillau, C, Amigues, B, Roussel, A, Leone, P, Gaubert, A, Pelosi, P.
Deposit date:2021-03-23
Release date:2021-07-07
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:A new non-classical fold of varroa odorant-binding proteins reveals a wide open internal cavity.
Sci Rep, 11, 2021
7FE5
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BU of 7fe5 by Molmil
AvmM Catalyzes Macrocyclization in Alchivemycin A Biosynthesis
Descriptor: AvmM, CACODYLATE ION, CHLORIDE ION
Authors:Zhang, B, Ge, H.M.
Deposit date:2021-07-19
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:AvmM catalyses macrocyclization through dehydration/Michael-type addition in alchivemycin A biosynthesis.
Nat Commun, 13, 2022
4I3R
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BU of 4i3r by Molmil
Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
Authors:Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D.
Deposit date:2012-11-26
Release date:2013-01-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013

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